Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis
Pedicone, Chiara, Fernandes, Sandra, Dungan, Otto M, Dormann, Shawn M, Viernes, Dennis R, Adhikari, Arijit A, Choi, Lydia B, De Jong, Ebbing P, Chisholm, John D, Kerr, William G
Published in Journal of cell science (10.01.2020)
Published in Journal of cell science (10.01.2020)
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Journal Article
Structure-Activity Studies on Bis-Sulfonamide SHIP1 Activators
Meyer, Shea T, Fernandes, Sandra, Anderson, Robert E, Pacherille, Angela, Toms, Bonnie, Kerr, William G, Chisholm, John D
Published in Molecules (Basel, Switzerland) (01.12.2023)
Published in Molecules (Basel, Switzerland) (01.12.2023)
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Journal Article
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
Pardoll, Drew, Yu, Hua, Kortylewski, Marcin, Kujawski, Maciej, Wang, Tianhong, Wei, Sheng, Zhang, Shumin, Pilon-Thomas, Shari, Niu, Guilian, Kay, Heidi, Mulé, James, Kerr, William G, Jove, Richard
Published in Nature medicine (01.12.2005)
Published in Nature medicine (01.12.2005)
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Journal Article
Role of SHIP1 in cancer and mucosal inflammation
Fernandes, Sandra, Iyer, Sonia, Kerr, William G.
Published in Annals of the New York Academy of Sciences (01.03.2013)
Published in Annals of the New York Academy of Sciences (01.03.2013)
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Journal Article
SHIP-1 Couples to the Dectin-1 hemITAM and Selectively Modulates Reactive Oxygen Species Production in Dendritic Cells in Response to Candida albicans
Blanco-Menéndez, Noelia, Del Fresno, Carlos, Fernandes, Sandra, Calvo, Enrique, Conde-Garrosa, Ruth, Kerr, William G, Sancho, David
Published in The Journal of immunology (1950) (01.11.2015)
Published in The Journal of immunology (1950) (01.11.2015)
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Journal Article
N1 -Benzyl Tryptamine Pan-SHIP1/2 Inhibitors: Synthesis and Preliminary Biological Evaluation as Anti-Tumor Agents
Fernandes, Sandra, Meyer, Shea T, Shah, Jigisha P, Adhikari, Arijit A, Kerr, William G, Chisholm, John D
Published in Molecules (Basel, Switzerland) (02.12.2022)
Published in Molecules (Basel, Switzerland) (02.12.2022)
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Journal Article
Targeting SHIP1 and SHIP2 in Cancer
Pedicone, Chiara, Meyer, Shea T, Chisholm, John D, Kerr, William G
Published in Cancers (20.02.2021)
Published in Cancers (20.02.2021)
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Journal Article
Selective deletion of SHIP-1 in hematopoietic cells in mice leads to severe lung inflammation involving ILC2 cells
Ye, Xujun, Zhang, Fengrui, Zhou, Li, Wei, Yadong, Zhang, Li, Wang, Lihui, Tang, Haiying, Chen, Zi, Kerr, William G, Zheng, Tao, Zhu, Zhou
Published in Scientific reports (28.04.2021)
Published in Scientific reports (28.04.2021)
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Journal Article
SHIP1 Inhibition Increases Immunoregulatory Capacity and Triggers Apoptosis of Hematopoietic Cancer Cells
Brooks, Robert, Fuhler, Gwenny M, Iyer, Sonia, Smith, Michelle J, Park, Mi-Young, Paraiso, Kim H. T, Engelman, Robert W, Kerr, William G
Published in The Journal of immunology (1950) (01.04.2010)
Published in The Journal of immunology (1950) (01.04.2010)
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Journal Article
Therapeutic potential of SH2 domain-containing inositol-5'-phosphatase 1 (SHIP1) and SHIP2 inhibition in cancer
Fuhler, Gwenny M, Brooks, Robert, Toms, Bonnie, Iyer, Sonia, Gengo, Elizabeth A, Park, Mi-Young, Gumbleton, Matthew, Viernes, Dennis R, Chisholm, John D, Kerr, William G
Published in Molecular medicine (Cambridge, Mass.) (01.01.2012)
Published in Molecular medicine (Cambridge, Mass.) (01.01.2012)
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Journal Article
SHIP1 Deficiency in Inflammatory Bowel Disease Is Associated With Severe Crohn's Disease and Peripheral T Cell Reduction
Fernandes, Sandra, Srivastava, Neetu, Sudan, Raki, Middleton, Frank A, Shergill, Amandeep K, Ryan, James C, Kerr, William G
Published in Frontiers in immunology (22.05.2018)
Published in Frontiers in immunology (22.05.2018)
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Journal Article
Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation
Hoekstra, Elmer, Das, Asha M, Willemsen, Marcella, Swets, Marloes, Kuppen, Peter J K, van der Woude, Christien J, Bruno, Marco J, Shah, Jigisha P, Ten Hagen, Timo L M, Chisholm, John D, Kerr, William G, Peppelenbosch, Maikel P, Fuhler, Gwenny M
Published in Oncotarget (08.11.2016)
Published in Oncotarget (08.11.2016)
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Journal Article
Analysis of SHIP1 expression and activity in Crohn's disease patients
Somasundaram, Rajesh, Fernandes, Sandra, Deuring, Jasper J, de Haar, Colin, Kuipers, Ernst J, Vogelaar, Lauran, Middleton, Frank A, van der Woude, C Janneke, Peppelenbosch, Maikel P, Kerr, William G, Fuhler, Gwenny M
Published in PloS one (02.08.2017)
Published in PloS one (02.08.2017)
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Journal Article
Mouse natural killer cell development and maturation are differentially regulated by SHIP-1
Banh, Cindy, Miah, S. M. Shahjahan, Kerr, William G., Brossay, Laurent
Published in Blood (29.11.2012)
Published in Blood (29.11.2012)
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Journal Article
Quorum sensing contributes to activated IgM-secreting B cell homeostasis
Montaudouin, Caroline, Anson, Marie, Hao, Yi, Duncker, Susanne V, Fernandez, Tahia, Gaudin, Emmanuelle, Ehrenstein, Michael, Kerr, William G, Colle, Jean-Hervé, Bruhns, Pierre, Daëron, Marc, Freitas, António A
Published in The Journal of immunology (1950) (01.01.2013)
Published in The Journal of immunology (1950) (01.01.2013)
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Journal Article
Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment
Fernandes, Sandra, Srivastava, Neetu, Pedicone, Chiara, Sudan, Raki, Luke, Elizabeth A., Dungan, Otto M., Pacherille, Angela, Meyer, Shea T., Dormann, Shawn, Schurmans, Stéphane, Chambers, Benedict J., Chisholm, John D., Kerr, William G.
Published in iScience (17.02.2023)
Published in iScience (17.02.2023)
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