Discovery of [ 11 C]MK-8056: A Selective PET Imaging Agent for the Study of mGluR 2 Negative Allosteric Modulators
Perkins, James J, McQuade, Paul, Bungard, Christopher J, Diamond, Tracy L, Gantert, Liza T, Gotter, Anthony L, Hanney, Barbara, Hills, Ivory D, Hurzy, Danielle M, Joshi, Aniket, Kern, Jonathan T, Schlegel, Kelly-Ann S, Manikowski, Jesse J, Meng, Zhaoyang, O'Brien, Julie A, Roecker, Anthony J, Smith, Sean M, Uslaner, Jason M, Hostetler, Eric, Meissner, Robert S
Published in ACS medicinal chemistry letters (13.07.2023)
Published in ACS medicinal chemistry letters (13.07.2023)
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Journal Article
Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator
Rudd, Michael T., Manley, Peter J., Hanney, Barbara, Meng, Zhaoyang, Shu, Youheng, de Leon, Pablo, Frie, Jessica L., Han, Yongxin, Wai, Jenny Miu-Chun, Yang, Zhi-Qiang, Perkins, James J., Hurzy, Danielle M., Manikowski, Jesse J., Zhu, Hong, Bungard, Christopher J., Converso, Antonella, Meissner, Robert S., Cosden, Mali L., Hayashi, Ikuo, Ma, Lei, O’Brien, Julie, Uebele, Victor N., Schachter, Joel B., Bhandari, Neetesh, Ward, Gwendolyn J., Fillgrove, Kerry L., Lu, Bing, Liang, Yuexia, Dubost, David C., Puri, Vanita, Eddins, Donnie M., Vardigan, Joshua D., Drolet, Robert E., Kern, Jonathan T., Uslaner, Jason M.
Published in ACS medicinal chemistry letters (10.08.2023)
Published in ACS medicinal chemistry letters (10.08.2023)
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Journal Article
Proteomic fingerprinting of Neotropical hard tick species (Acari: Ixodidae) using a self-curated mass spectra reference library
Gittens, Rolando A, Almanza, Alejandro, Bennett, Kelly L, Mejía, Luis C, Sanchez-Galan, Javier E, Merchan, Fernando, Kern, Jonathan, Miller, Matthew J, Esser, Helen J, Hwang, Robert, Dong, May, De León, Luis F, Álvarez, Eric, Loaiza, Jose R
Published in PLoS neglected tropical diseases (01.10.2020)
Published in PLoS neglected tropical diseases (01.10.2020)
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Journal Article
Potent, selective and orally bioavailable leucine-rich repeat kinase 2 (LRRK2) inhibitors
Greshock, Thomas J., Sanders, John M., Drolet, Robert E., Rajapakse, Hemaka A., Chang, Ronald K., Kim, Boyoung, Rada, Vanessa L., Tiscia, Heather E., Su, Hua, Lai, Ming-Tain, Sur, Sylvie M., Sanchez, Rosa I., Bilodeau, Mark T., Renger, John J., Kern, Jonathan T., McCauley, John A.
Published in Bioorganic & medicinal chemistry letters (01.06.2016)
Published in Bioorganic & medicinal chemistry letters (01.06.2016)
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Journal Article
Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity
Nikonova, Elena V., Xiong, Yulan, Tanis, Keith Q., Dawson, Valina L., Vogel, Robert L., Finney, Eva M., Stone, David J., Reynolds, Ian J., Kern, Jonathan T., Dawson, Ted M.
Published in Human molecular genetics (01.01.2012)
Published in Human molecular genetics (01.01.2012)
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Journal Article
Simian Virus 40 Large T-Antigen G-Quadruplex DNA Helicase Inhibition by G-Quadruplex DNA-Interactive Agents
Tuesuwan, Bodin, Kern, Jonathan T., Thomas, Pei Wang, Rodriguez, Mireya, Li, Jing, David, Wendi M., Kerwin, Sean M.
Published in Biochemistry (Easton) (19.02.2008)
Published in Biochemistry (Easton) (19.02.2008)
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Journal Article
Evaluation of Binding of Perylene Diimide and Benzannulated Perylene Diimide Ligands to DNA by Electrospray Ionization Mass Spectrometry
Mazzitelli, Carolyn L., Brodbelt, Jennifer S., Kern, Jonathan T., Rodriguez, Mireya, Kerwin, Sean M.
Published in Journal of the American Society for Mass Spectrometry (01.04.2006)
Published in Journal of the American Society for Mass Spectrometry (01.04.2006)
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Journal Article
Disruption of the Keap1-containing ubiquitination complex as an antioxidant therapy
Kern, Jonathan T, Hannink, Mark, Hess, J Fred
Published in Current topics in medicinal chemistry (01.05.2007)
Published in Current topics in medicinal chemistry (01.05.2007)
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Journal Article
Perylene Diimide G-Quadruplex DNA Binding Selectivity is Mediated by Ligand Aggregation
Kerwin, Sean M., Chen, Grace, Kern, Jonathan T., Thomas, Pei Wang
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
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Journal Article
Internet of Wine: A Low-cost Solution for Stock Management Improvement
Mathieu, Acchiardi, Kern, Jonathan, Ferre, Guillaume
Published in 2018 25th IEEE International Conference on Electronics, Circuits and Systems (ICECS) (01.12.2018)
Published in 2018 25th IEEE International Conference on Electronics, Circuits and Systems (ICECS) (01.12.2018)
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Conference Proceeding
G-Quadruplex DNA binding by a series of carbocyanine dyes
Kerwin, Sean M., Sun, Daekyu, Kern, Jonathan T., Rangan, Anupama, Thomas, Pei Wang
Published in Bioorganic & medicinal chemistry letters (17.09.2001)
Published in Bioorganic & medicinal chemistry letters (17.09.2001)
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Journal Article
HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev response element region
Heaphy, Shaun, Dingwall, Colin, Ernberg, Ingemar, Gait, Michaet J., Green, Sheila M., Kern, Jonathan, Lowe, Anthony D., Singh, Mohinder, Skinner, Michael A.
Published in Cell (23.02.1990)
Published in Cell (23.02.1990)
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Journal Article