A Novel mTORC1/2 Inhibitor (MTI-31) Inhibits Tumor Growth, Epithelial-Mesenchymal Transition, Metastases, and Improves Antitumor Immunity in Preclinical Models of Lung Cancer
Zhang, Qianwen, Zhang, Yan, Chen, Yaqing, Qian, Jianchang, Zhang, Xuesai, Yu, Ker
Published in Clinical cancer research (15.06.2019)
Published in Clinical cancer research (15.06.2019)
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Discovery of a novel, potent and selective small‐molecule inhibitor of PD‐1/PD‐L1 interaction with robust in vivo anti‐tumour efficacy
Liu, Chenglong, Zhou, Feilong, Yan, Ziqin, Shen, Lian, Zhang, Xichen, He, Fenglian, Wang, Heng, Lu, Xiaojie, Yu, Ker, Zhao, Yujun, Zhu, Di
Published in British journal of pharmacology (01.07.2021)
Published in British journal of pharmacology (01.07.2021)
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LS‐106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
Liu, Yingqiang, Lai, Mengzhen, Li, Shan, Wang, Yanan, Feng, Fang, Zhang, Tao, Tong, Linjiang, Zhang, Mengge, Chen, Hao, Chen, Yi, Song, Peiran, Li, Yan, Bai, Gang, Ning, Yi, Tang, Haotian, Fang, Yan, Chen, Yi, Lu, Xiaoyun, Geng, Meiyu, Ding, Ke, Yu, Ker, Xie, Hua, Ding, Jian
Published in Cancer science (01.02.2022)
Published in Cancer science (01.02.2022)
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Robust mixed performance of uncertain switched systems with interval time‐varying delay by synchronous switching on signal and sampled‐data input
Lien, Chang‐Hua, Chang, Hao‐Chin, Yu, Ker‐Wei, Li, Hung‐Chi, Hou, Yi‐You
Published in International journal of robust and nonlinear control (25.01.2022)
Published in International journal of robust and nonlinear control (25.01.2022)
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Novel-smoothened inhibitors for therapeutic targeting of naïve and drug-resistant hedgehog pathway-driven cancers
Li, Qing-rou, Zhao, Hui, Zhang, Xue-sai, Lang, Henk, Yu, Ker
Published in Acta pharmacologica Sinica (01.02.2019)
Published in Acta pharmacologica Sinica (01.02.2019)
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Ammonia derived from glutaminolysis is a diffusible regulator of autophagy
Eng, Christina H, Yu, Ker, Lucas, Judy, White, Eileen, Abraham, Robert T
Published in Science signaling (27.04.2010)
Published in Science signaling (27.04.2010)
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BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer
Wang, Xiaoshuang, Feng, Mei, Xiao, Tengfei, Guo, Baosen, Liu, Danyang, Liu, Chenglong, Pei, Jinpeng, Liu, Qiaofeng, Xiao, Yi, Rosin-Arbesfeld, Rina, Shi, Ying, Zhou, Yang, Yang, Mengxuan, Feng, Yu-Xiong, Jiang, Yizhou, Shao, Zhimin, Yu, Ker, Zhu, Di
Published in Oncogene (22.04.2021)
Published in Oncogene (22.04.2021)
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Targeting mTOR globally in cancer: Thinking beyond rapamycin
Shor, Boris, Gibbons, James J., Abraham, Robert T., Yu, Ker
Published in Cell cycle (Georgetown, Tex.) (01.12.2009)
Published in Cell cycle (Georgetown, Tex.) (01.12.2009)
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Requirement of the mTOR Kinase for the Regulation of Maf1 Phosphorylation and Control of RNA Polymerase III-dependent Transcription in Cancer Cells
Shor, Boris, Wu, Jiang, Shakey, Quazi, Toral-Barza, Lourdes, Shi, Celine, Follettie, Max, Yu, Ker
Published in The Journal of biological chemistry (14.05.2010)
Published in The Journal of biological chemistry (14.05.2010)
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Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function
Jin, Rui, Liu, Liang, Xing, Yun, Meng, Tao, Ma, Lanping, Pei, Jinpeng, Cong, Ying, Zhang, Xuesai, Ren, Zhiqiang, Wang, Xin, Shen, Jingkang, Yu, Ker
Published in Molecular cancer therapeutics (01.11.2020)
Published in Molecular cancer therapeutics (01.11.2020)
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BK ablation attenuates osteoblast bone formation via integrin pathway
Wang, Yinhang, Guo, Qiang, Hei, Hongya, Tao, Jie, Zhou, Yi, Dong, Jibin, Xin, Hong, Cai, Hui, Gao, Jianjun, Yu, Ker, Reilly, Svetlana, Yin, Peihao, Zhang, Xuemei
Published in Cell death & disease (30.09.2019)
Published in Cell death & disease (30.09.2019)
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Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin
KER YU, TORAL-BARZA, Lourdes, COLE, Derek C, ELLINGBOE, John, AYRAL-KALOUSTIAN, Semiramis, MANSOUR, Tarek S, GIBBONS, James J, ABRAHAM, Robert T, NOWAK, Pawel, ZASK, Arie, SHI, Celine, ZHANG, Wei-Guo, LUCAS, Judy, SHOR, Boris, KIM, Jamie, VERHEIJEN, Jeroen, CURRAN, Kevin, MALWITZ, David J
Published in Cancer research (Chicago, Ill.) (01.08.2009)
Published in Cancer research (Chicago, Ill.) (01.08.2009)
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RORγt agonist enhances anti-PD-1 therapy by promoting monocyte-derived dendritic cells through CXCL10 in cancers
Xia, Li, Tian, Enming, Yu, Mingcheng, Liu, Chenglong, Shen, Lian, Huang, Yafei, Wu, Zhongen, Tian, Jinlong, Yu, Ker, Wang, Yonghui, Xie, Qiong, Zhu, Di
Published in Journal of experimental & clinical cancer research (23.04.2022)
Published in Journal of experimental & clinical cancer research (23.04.2022)
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Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer
Deng, Yan, Hu, Jia-chun, He, Shu-hua, Lou, Bin, Ding, Ting-bo, Yang, Jin-tong, Mo, Ming-guang, Ye, De-yong, Zhou, Lu, Jiang, Xian-cheng, Yu, Ker, Dong, Ji-bin
Published in Acta pharmacologica Sinica (01.01.2021)
Published in Acta pharmacologica Sinica (01.01.2021)
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mTOR Promotes Tissue Factor Expression and Activity in EGFR-Mutant Cancer
Cong, Ying, Li, Qingrou, Zhang, Xuesai, Chen, Yaqing, Yu, Ker
Published in Frontiers in oncology (14.08.2020)
Published in Frontiers in oncology (14.08.2020)
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