Discovery and Synthesis of [6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]- 2-(4-hydroxyphenyl)]benzo[b]thiophene: A Novel, Highly Potent, Selective Estrogen Receptor Modulator
Palkowitz, Alan D, Glasebrook, Andrew L, Thrasher, K. Jeff, Hauser, Kenneth L, Short, Lorri L, Phillips, D. Lynn, Muehl, Brian S, Sato, Masahiko, Shetler, Pamela K, Cullinan, George J, Pell, Tina R, Bryant, Henry U
Published in Journal of medicinal chemistry (09.05.1997)
Published in Journal of medicinal chemistry (09.05.1997)
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Journal Article
Structural Evolution and Pharmacology of a Novel Series of Triacid Angiotensin II Receptor Antagonists
Palkowitz, Alan D, Steinberg, Mitchell I, Thrasher, K. Jeff, Reel, Jon K, Hauser, Kenneth L, Zimmerman, Karen M, Wiest, Sally A, Whitesitt, Celia A, Simon, Richard L
Published in Journal of medicinal chemistry (01.12.1994)
Published in Journal of medicinal chemistry (01.12.1994)
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Journal Article
A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine
Wong, D T, Horng, J S, Bymaster, F P, Hauser, K L, Molloy, B B
Published in Life sciences (1973) (01.08.1974)
Published in Life sciences (1973) (01.08.1974)
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Dibasic Benzo[b]thiophene Derivatives as a Novel Class of Active Site-Directed Thrombin Inhibitors. 1. Determination of the Serine Protease Selectivity, Structure−Activity Relationships, and Binding Orientation
Sall, Daniel J, Bastian, Jolie A, Briggs, Stephen L, Buben, John A, Chirgadze, Nickolay Y, Clawson, David K, Denney, Michael L, Giera, Deborah D, Gifford-Moore, Donetta S, Harper, Richard W, Hauser, Kenneth L, Klimkowski, Valentine J, Kohn, Todd J, Lin, Ho-Shen, McCowan, Jefferson R, Palkowitz, Alan D, Smith, Gerald F, Takeuchi, Kumiko, Thrasher, Kenneth J, Tinsley, Jennifer M, Utterback, Barbara G, Yan, Sau-Chi B, Zhang, Minsheng
Published in Journal of medicinal chemistry (24.10.1997)
Published in Journal of medicinal chemistry (24.10.1997)
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Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146
Norman, Bryan H., Dantzig, Anne H., Kroin, Julian S., Law, Kevin L., Tabas, Linda B., Shepard, Robert L., Palkowitz, Alan D., Hauser, Kenneth L., Winter, Mark A., Sluka, James P., Starling, James J.
Published in Bioorganic & medicinal chemistry letters (06.12.1999)
Published in Bioorganic & medicinal chemistry letters (06.12.1999)
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Journal Article
Synthesis and pharmacological evaluation of a novel series of 5-aryl benzimidazole angiotensin II receptor antagonists
Palkowitz, Alan D., Steinberg, Mitchell I., Zimmerman, Karen M., Thrasher, K.Jeff, Hauser, Kenneth L., Boyd, Donald B.
Published in Bioorganic & medicinal chemistry letters (04.05.1995)
Published in Bioorganic & medicinal chemistry letters (04.05.1995)
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Journal Article
PROCESS FOR 2-SUBSTITUTED BENZO[B]THIOPHENE COMPOUNDS AND INTERMEDIATES THEREOF
HAUSER,KENNETH L, THRASHER,KENNETH J, PALKOWITZ,ALAN D, SALL,DANIEL J
Year of Publication 28.09.1999
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Year of Publication 28.09.1999
Patent
Process for 2-substituted benzo{b}thiophene compounds and intermediates thereof
ALAN D. PALKOWITZ, KENNETH J. THRASHER, DANIEL J. SALL, KENNETH L. HAUSER
Year of Publication 03.12.1998
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Year of Publication 03.12.1998
Patent
Process for preparing 2-substituted benzo [B] Thiophene compounds and intermediates thereof
PALKOWITZ; ALAN D, SALL; DANIEL J, THRASHER; KENNETH J, HAUSER; KENNETH L
Year of Publication 27.01.1998
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Year of Publication 27.01.1998
Patent
Process for preparing 2-substituted benzo[B]thiophene compounds and intermediates thereof
PALKOWITZ; ALAN D, SALL; DANIEL J, THRASHER; KENNETH J, HAUSER; KENNETH L
Year of Publication 20.01.1998
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Year of Publication 20.01.1998
Patent
Fremgangsmåte for fremstilling av 2-substituerte benzo(b)-tiofenforbindelser og mellomprodukter
HAUSER, KENNETH L, SALL, DANIEL JON, PALKOWITZ, ALAN D, THRASHER, KENNETH JEFF
Year of Publication 23.09.1997
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Year of Publication 23.09.1997
Patent
Process for preparing 2-substituted benzo[b]thiophene compounds and intermediates thereof
PALKOWITZ; ALAN D, SALL; DANIEL J, THRASHER; KENNETH J, HAUSER; KENNETH L
Year of Publication 25.03.1997
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Year of Publication 25.03.1997
Patent
Process for 2-substituted benzoÝb¨thiophene compounds and in termediates thereof
ALAN D. PALKOWITZ, KENNETH J. THRASHER, DANIEL J. SALL, KENNETH L. HAUSER
Year of Publication 16.10.1996
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Year of Publication 16.10.1996
Patent
PROCESS FOR 2-SUBSTITUTED BENZO[b]THIOPHENE COMPOUNDS AND INTERMEDIATES THEREOF
PALKOWITZ, ALAN, D, HAUSER, KENNETH, L, SALL, DANIEL, J, THRASHER, KENNETH, J
Year of Publication 03.10.1996
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Year of Publication 03.10.1996
Patent
NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL AGENT, METHOD OF OBTAINING SUCH NOVEL HETEROCYCLIC COMPOUNDS AND INITIAL COMPOUNDS FOR OBTAINING THEM
REEL JON K, MARSHALL WINSTON S, PALKOWITZ ALAN D, SIMON RICHARD L, LIFER SHERRYL L, BOYD DONALD B, HAUSER KENNETH L, WHITESITT CELIA A, TAKEUCHI KUMIKO, THRASHER KENNETH J, PFEIFER WILLIAM, STEINBERG MITCHELL I
Year of Publication 27.02.1998
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Year of Publication 27.02.1998
Patent
PROSTAGLANDIN SYNTHESIS
DOUGLAS O. SPRY, RICHARD A. MUELLER, KENNETH L. HAUSER, ROBERT B. MORIN
Year of Publication 22.02.1972
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Year of Publication 22.02.1972
Patent
Angiotensin II antagonists
PALKOWITZ; ALAN D, STEINBERG; MITCHELL I, WHITESITT; CELIA A, THRASHER; K. JEFF, BOYD; DONALD B, PFEIFER; WILLIAM, REEL; JON K, HAUSER; KENNETH L, TAKEUCHI; KUMIKO, LIFER; SHERRYL L, MARSHALL; WINSTON S, SIMON; RICHARD L
Year of Publication 16.01.1996
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Year of Publication 16.01.1996
Patent
Angiotensin II antagonists
PALKOWITZ; ALAN D, STEINBERG; MITCHELL I, WHITESITT; CELIA A, THRASHER; K. JEFF, BOYD; DONALD B, PFEIFER; WILLIAM, REEL; JON K, HAUSER; KENNETH L, TAKEUCHI; KUMIKO, LIFER; SHERRYL L, MARSHALL; WINSTON S, SIMON; RICHARD L
Year of Publication 28.03.1995
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Year of Publication 28.03.1995
Patent
ANGIOTENSIN II ANTAGONISTS
SIMON, RICHARD L, TAKEUCHI, KUMIKO, BOYD, DONALD B, THRASHER, KENNETH J, WHITESITT, CELIA A, REEL, JON K, HAUSER, KENNETH L, PFEIFER, WILLIAM, LIFER, SHERRYL L, PALKOWITZ, ALAN D, STEINBERG, MITCHELL I, MARSHALL, WINSTON S
Year of Publication 04.12.1993
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Year of Publication 04.12.1993
Patent