Brivaracetam: Rationale for discovery and preclinical profile of a selective SV2A ligand for epilepsy treatment
Klitgaard, Henrik, Matagne, Alain, Nicolas, Jean‐Marie, Gillard, Michel, Lamberty, Yves, De Ryck, Marc, Kaminski, Rafal M., Leclercq, Karine, Niespodziany, Isabelle, Wolff, Christian, Wood, Martyn, Hannestad, Jonas, Kervyn, Sophie, Kenda, Benoit
Published in Epilepsia (Copenhagen) (01.04.2016)
Published in Epilepsia (Copenhagen) (01.04.2016)
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SV2A protein is a broad-spectrum anticonvulsant target: Functional correlation between protein binding and seizure protection in models of both partial and generalized epilepsy
Kaminski, Rafal M., Matagne, Alain, Leclercq, Karine, Gillard, Michel, Michel, Philippe, Kenda, Benoit, Talaga, Patrice, Klitgaard, Henrik
Published in Neuropharmacology (01.03.2008)
Published in Neuropharmacology (01.03.2008)
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Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands
Mercier, Joël, Archen, Laurence, Bollu, Véronique, Carré, Stéphane, Evrard, Yves, Jnoff, Eric, Kenda, Benoît, Lallemand, Bénédicte, Michel, Philippe, Montel, Florian, Moureau, Florence, Price, Nathalie, Quesnel, Yannick, Sauvage, Xavier, Valade, Anne, Provins, Laurent
Published in ChemMedChem (01.04.2014)
Published in ChemMedChem (01.04.2014)
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Discovery of 4-Substituted Pyrrolidone Butanamides as New Agents with Significant Antiepileptic Activity
Kenda, Benoit M, Matagne, Alain C, Talaga, Patrice E, Pasau, Patrick M, Differding, Edmond, Lallemand, Bénédicte I, Frycia, Anne M, Moureau, Florence G, Klitgaard, Henrik V, Gillard, Michel R, Fuks, Bruno, Michel, Philippe
Published in Journal of medicinal chemistry (29.01.2004)
Published in Journal of medicinal chemistry (29.01.2004)
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Profile of the new pyrrolidone derivative seletracetam (ucb 44212) in animal models of epilepsy
Matagne, Alain, Margineanu, Doru-Georg, Potschka, Heidrun, Löscher, Wolfgang, Michel, Philippe, Kenda, Benoit, Klitgaard, Henrik
Published in European journal of pharmacology (01.07.2009)
Published in European journal of pharmacology (01.07.2009)
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Journal Article
Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands
Mercier, Joël, Archen, Laurence, Bollu, Véronique, Carre, Stéphane, Evrard, Yves, Jnoff, Eric, Kenda, Benoît, Lallemand, Bénédicte, Michel, Philippe, Montel, Florian, Moureau, Florence, Price, Nathalie, Quesnel, Yannick, Sauvage, Xavier, Valade, Anne, Provins, Laurent
Published in ChemMedChem (01.04.2014)
Published in ChemMedChem (01.04.2014)
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[ super(11)C]UCB-A, a novel PET tracer for synaptic vesicle protein 2 A
Estradaa, Sergio, Lubberinkb, Mark, Thibblinb, Alf, Sprychad, Margareta, Buchanane, Tim, Mestdaghe, Nathalie, Kendae, Benoit, Merciere, Joel, Provinse, Laurent, Gillarde, Michel, Tytgate, Dominique, Antonia, Gunnar
Published in Nuclear medicine and biology (01.06.2016)
Published in Nuclear medicine and biology (01.06.2016)
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Journal Article
Brivaracetam: Rationale for discovery and preclinical profile of a selective SV 2A ligand for epilepsy treatment
Klitgaard, Henrik, Matagne, Alain, Nicolas, Jean‐Marie, Gillard, Michel, Lamberty, Yves, De Ryck, Marc, Kaminski, Rafal M., Leclercq, Karine, Niespodziany, Isabelle, Wolff, Christian, Wood, Martyn, Hannestad, Jonas, Kervyn, Sophie, Kenda, Benoit
Published in Epilepsia (Copenhagen) (01.04.2016)
Published in Epilepsia (Copenhagen) (01.04.2016)
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Journal Article
[11C]UCB-A, a novel PET tracer for synaptic vesicle protein 2A
Estrada, Sergio, Lubberink, Mark, Thibblin, Alf, Sprycha, Margareta, Buchanan, Tim, Mestdagh, Nathalie, Kenda, Benoit, Mercier, Joel, Provins, Laurent, Gillard, Michel, Tytgat, Dominique, Antoni, Gunnar
Published in Nuclear medicine and biology (01.06.2016)
Published in Nuclear medicine and biology (01.06.2016)
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Journal Article
[11 C]UCB-A, a n3ovel PET tracer for synaptic vesicle protein 2A
Estrada, Sergio, Lubberink, Mark, Thibblin, Alf, Sprycha, Margareta, Buchanan, Tim, Mestdagh, Nathalie, Kenda, Benoit, Mercier, Joel, Provins, Laurent, Gillard, Michel, Tytgat, Dominique, Antoni, Gunnar
Published in Nuclear medicine and biology (2016)
Published in Nuclear medicine and biology (2016)
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Journal Article
2-Oxo-1-pyrrolidine derivatives, process of their preparation and their use
DIFFERDING EDMOND, LALLEMAND BÉNÉDICTE, MICHEL PHILLIPPE, PASAU PATRICK, MATAGNE ALAIN, KENDA BENOIT KENDA, TALAGA PATRICE
Year of Publication 30.04.2014
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Year of Publication 30.04.2014
Patent
Discovery of Indolone Acetamides as Novel SV2A Ligands with Improved Potency Toward Seizure Suppression
Frycia, Anne, Starck, Jean-Philippe, Jadot, Sophie, Lallemand, Bénédicte, Leclercq, Karine, Lo Brutto, Patrick, Matagne, Alain, Verbois, Valérie, Mercier, Joël, Kenda, Benoit
Published in ChemMedChem (01.02.2010)
Published in ChemMedChem (01.02.2010)
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Cover Picture: Discovery of Indolone Acetamides as Novel SV2A Ligands with Improved Potency Toward Seizure Suppression (ChemMedChem 2/2010)
Frycia, Anne, Starck, Jean-Philippe, Jadot, Sophie, Lallemand, Bénédicte, Leclercq, Karine, Lo Brutto, Patrick, Matagne, Alain, Verbois, Valérie, Mercier, Joël, Kenda, Benoit
Published in ChemMedChem (01.02.2010)
Published in ChemMedChem (01.02.2010)
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Journal Article
2-Oxo-1-pyrrolidine derivatives, process of their preparation and their use
DIFFERDING EDMOND, MICHEL PHILLIPPE, PASAU PATRICK, MATAGNE ALAIN, LALLEMAND BENEDICTE, KENDA BENOIT KENDA, TALAGA PATRICE
Year of Publication 12.02.2003
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Year of Publication 12.02.2003
Patent
CRM1 inhibitors for treating epilepsy
Lee, Margaret, Leclercq, Karine, Tamir, Sharon, Kenda, Benoit, De Ryck, Marc, Kaminski, Rafal M
Year of Publication 14.03.2023
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Year of Publication 14.03.2023
Patent
Stereoselective syntheses of 1,2-dialkyl-1-phenyl cyclopentanes involving intramolecular carbolithiation of olefins
Krief, Alain, Kenda, Benoît, Maertens, Christophe, Remacle, Bruno
Published in Tetrahedron (20.05.1996)
Published in Tetrahedron (20.05.1996)
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Dendrophanes: Water-soluble dendritic receptors as models for buried recognition sites in globular proteins
Mattei, S, Wallimann, P, Kenda, B, Amrein, W, Diederich, F
Published in Helvetica chimica acta (15.12.1997)
Published in Helvetica chimica acta (15.12.1997)
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