Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours
Hong, David S, Kang, Yoon-Koo, Borad, Mitesh, Sachdev, Jasgit, Ejadi, Samuel, Lim, Ho Yeong, Brenner, Andrew J, Park, Keunchil, Lee, Jae-Lyun, Kim, Tae-You, Shin, Sangjoon, Becerra, Carlos R, Falchook, Gerald, Stoudemire, Jay, Martin, Desiree, Kelnar, Kevin, Peltier, Heidi, Bonato, Vinicius, Bader, Andreas G, Smith, Susan, Kim, Sinil, O'Neill, Vincent, Beg, Muhammad S
Published in British journal of cancer (01.05.2020)
Published in British journal of cancer (01.05.2020)
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The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
Tang, Dean G, Liu, Can, Kelnar, Kevin, Liu, Bigang, Chen, Xin, Calhoun-Davis, Tammy, Li, Hangwen, Patrawala, Lubna, Yan, Hong, Jeter, Collene, Honorio, Sofia, Wiggins, Jason F, Bader, Andreas G, Fagin, Randy, Brown, David
Published in Nature medicine (01.02.2011)
Published in Nature medicine (01.02.2011)
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The let-7 MicroRNA represses cell proliferation pathways in human cells
JOHNSON, Charles D, ESQUELA-KERSCHER, Aurora, CHIN, Lena, BROWN, David, SLACK, Frank J, STEFANI, Giovanni, BYROM, Mike, KELNAR, Kevin, OVCHARENKO, Dmitriy, WILSON, Mike, XIAOWEI WANG, SHELTON, Jeffrey, SHINGARA, Jaclyn
Published in Cancer research (Chicago, Ill.) (15.08.2007)
Published in Cancer research (Chicago, Ill.) (15.08.2007)
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Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes
Takeshita, Fumitaka, Patrawala, Lubna, Osaki, Mitsuhiko, Takahashi, Ryou-u, Yamamoto, Yusuke, Kosaka, Nobuyoshi, Kawamata, Masaki, Kelnar, Kevin, Bader, Andreas G., Brown, David, Ochiya, Takahiro
Published in Molecular therapy (01.01.2010)
Published in Molecular therapy (01.01.2010)
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Quantification of Therapeutic miRNA Mimics in Whole Blood from Nonhuman Primates
Kelnar, Kevin, Peltier, Heidi J, Leatherbury, Neil, Stoudemire, Jay, Bader, Andreas G
Published in Analytical chemistry (Washington) (04.02.2014)
Published in Analytical chemistry (Washington) (04.02.2014)
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High-throughput RNAi screening in vitro: from cell lines to primary cells
Ovcharenko, Dmitriy, Jarvis, Richard, Hunicke-Smith, Scott, Kelnar, Kevin, Brown, David
Published in RNA (Cambridge) (01.06.2005)
Published in RNA (Cambridge) (01.06.2005)
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PDL1 Regulation by p53 via miR-34
Cortez, Maria Angelica, Ivan, Cristina, Valdecanas, David, Wang, Xiaohong, Peltier, Heidi J, Ye, Yuping, Araujo, Luiz, Carbone, David P, Shilo, Konstantin, Giri, Dipak K, Kelnar, Kevin, Martin, Desiree, Komaki, Ritsuko, Gomez, Daniel R, Krishnan, Sunil, Calin, George A, Bader, Andreas G, Welsh, James W
Published in JNCI : Journal of the National Cancer Institute (01.01.2016)
Published in JNCI : Journal of the National Cancer Institute (01.01.2016)
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In vivo localization of miR-34 delivered via liposomal MRX34: chromogenic in situ hybridization (CISH) results in a preclinical model and liver biopsies from phase I patients
Martin, Desiree', Kelnar, Kevin, Bader, Andreas G.
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer
Kasinski, A L, Kelnar, K, Stahlhut, C, Orellana, E, Zhao, J, Shimer, E, Dysart, S, Chen, X, Bader, A G, Slack, F J
Published in Oncogene (01.07.2015)
Published in Oncogene (01.07.2015)
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Regression of murine lung tumors by the let-7 microRNA
TRANG, P, MEDINA, P. P, SLACK, F. J, WIGGINS, J. F, RUFFINO, L, KELNAR, K, OMOTOLA, M, HOMER, R, BROWN, D, BADER, A. G, WEIDHAAS, J. B
Published in Oncogene (18.03.2010)
Published in Oncogene (18.03.2010)
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Down-regulation of target gene expression in human white blood cells (hWBCs) by MRX34, a liposomal miR-34 mimic: Next generation sequencing (NGS) results from a first-in-human trial of microRNA cancer therapy
Kelnar, Kevin, Peltier, Heidi J., Bader, Andreas G.
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Effects of MRX34, a liposomal miR-34 mimic, on target gene expression in human white blood cells (hWBCs): qRT-PCR results from a first-in-human trial of microRNA cancer therapy
Peltier, Heidi J., Kelnar, Kevin, Bader, Andreas G.
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways
Cogswell, John P., Ward, James, Taylor, Ian A., Waters, Michelle, Shi, Yunling, Cannon, Brian, Kelnar, Kevin, Kemppainen, Jon, Brown, David, Chen, Caifu, Prinjha, Rab K., Richardson, Jill C., Saunders, Ann M., Roses, Allen D., Richards, Cynthia A.
Published in Journal of Alzheimer's disease (01.05.2008)
Published in Journal of Alzheimer's disease (01.05.2008)
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