Unsymmetrical Bisquinolines with High Potency against P. falciparum Malaria
Liebman, Katherine M, Burgess, Steven J, Gunsaru, Bornface, Kelly, Jane X, Li, Yuexin, Morrill, Westin, Liebman, Michael C, Peyton, David H
Published in Molecules (Basel, Switzerland) (10.05.2020)
Published in Molecules (Basel, Switzerland) (10.05.2020)
Get full text
Journal Article
Discovery of dual function acridones as a new antimalarial chemotype
Hinrichs, David J, Wittlin, Sergio, Cooper, Roland A, Riscoe, Michael K, Dodean, Rozalia A, Kelly, Jane X, Winter, Rolf, Smilkstein, Martin J, Janowsky, Aaron, Lane, Kristin D, Johnson, Robert A, Brun, Reto
Published in Nature (14.05.2009)
Published in Nature (14.05.2009)
Get full text
Journal Article
ELQ-331 as a prototype for extremely durable chemoprotection against malaria
Smilkstein, Martin J, Pou, Sovitj, Krollenbrock, Alina, Bleyle, Lisa A, Dodean, Rozalia A, Frueh, Lisa, Hinrichs, David J, Li, Yuexin, Martinson, Thomas, Munar, Myrna Y, Winter, Rolf W, Bruzual, Igor, Whiteside, Samantha, Nilsen, Aaron, Koop, Dennis R, Kelly, Jane X, Kappe, Stefan H I, Wilder, Brandon K, Riscoe, Michael K
Published in Malaria journal (27.08.2019)
Published in Malaria journal (27.08.2019)
Get full text
Journal Article
Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapy
Stickles, Allison M, Ting, Li-Min, Morrisey, Joanne M, Li, Yuexin, Mather, Michael W, Meermeier, Erin, Pershing, April M, Forquer, Isaac P, Miley, Galen P, Pou, Sovitj, Winter, Rolf W, Hinrichs, David J, Kelly, Jane X, Kim, Kami, Vaidya, Akhil B, Riscoe, Michael K, Nilsen, Aaron
Published in The American journal of tropical medicine and hygiene (03.06.2015)
Published in The American journal of tropical medicine and hygiene (03.06.2015)
Get full text
Journal Article
Optimization of endochin-like quinolones for antimalarial activity
Winter, Rolf, Kelly, Jane X., Smilkstein, Martin J., Hinrichs, David, Koop, Dennis R., Riscoe, Michael K.
Published in Experimental parasitology (01.02.2011)
Published in Experimental parasitology (01.02.2011)
Get full text
Journal Article
Design, Synthesis, and Evaluation of 10-N-Substituted Acridones as Novel Chemosensitizers in Plasmodium falciparum
KELLY, Jane X, SMILKSTEIN, Martin J, COOPER, Roland A, LANE, Kristin D, JOHNSON, Robert A, JANOWSKY, Aaron, DODEAN, Rozalia A, HINRICHS, David J, WINTER, Rolf, RISCOE, Michael
Published in Antimicrobial Agents and Chemotherapy (01.11.2007)
Published in Antimicrobial Agents and Chemotherapy (01.11.2007)
Get full text
Journal Article
Total Synthesis and Antimalarial Activity of 2‑(p‑Hydroxybenzyl)-prodigiosins, Isoheptylprodigiosin, and Geometric Isomers of Tambjamine MYP1 Isolated from Marine Bacteria
Kancharla, Papireddy, Li, Yuexin, Yeluguri, Monish, Dodean, Rozalia A, Reynolds, Kevin A, Kelly, Jane X
Published in Journal of medicinal chemistry (24.06.2021)
Published in Journal of medicinal chemistry (24.06.2021)
Get full text
Journal Article
Optimization of B‑Ring-Functionalized Antimalarial Tambjamines and Prodiginines
Kumar, Amrendra, Chithanna, Sivanna, Li, Yuexin, Zhang, Xiaowei, Dodean, Rozalia A., Caridha, Diana, Madejczyk, Michael S., Lee, Patricia J., Jin, Xiannu, Chetree, Ravi, Blount, Cameron, Dennis, William E., DeLuca, Jesse, Vuong, Chau, Pannone, Kristina, Dinh, Hieu T., Leed, Susan, Roth, Alison, Reynolds, Kevin A., Kelly, Jane X., Kancharla, Papireddy
Published in Journal of medicinal chemistry (19.10.2024)
Published in Journal of medicinal chemistry (19.10.2024)
Get full text
Journal Article
Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents
Kancharla, Papireddy, Ortiz, Diana, Fargo, Corinne M., Zhang, Xiaowei, Li, Yuexin, Sanchez, Marco, Kumar, Amrendra, Yeluguri, Monish, Dodean, Rozalia A., Caridha, Diana, Madejczyk, Michael S., Martin, Monica, Jin, Xiannu, Blount, Cameron, Chetree, Ravi, Pannone, Kristina, Dinh, Hieu T., DeLuca, Jesse, Evans, Martin, Nadeau, Robert, Vuong, Chau, Leed, Susan, Dennis, William E., Roncal, Norma, Pybus, Brandon S., Lee, Patricia J., Roth, Alison, Reynolds, Kevin A., Kelly, Jane X., Landfear, Scott M.
Published in Journal of medicinal chemistry (23.05.2024)
Published in Journal of medicinal chemistry (23.05.2024)
Get full text
Journal Article
Mutasynthesis of Fluorinated Pactamycin Analogues and Their Antimalarial Activity
Almabruk, Khaled H, Lu, Wanli, Li, Yuexin, Abugreen, Mostafa, Kelly, Jane X, Mahmud, Taifo
Published in Organic letters (05.04.2013)
Published in Organic letters (05.04.2013)
Get full text
Journal Article
Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc1 Inhibition Strategy for Malaria
Stickles, Allison M, Smilkstein, Martin J, Morrisey, Joanne M, Li, Yuexin, Forquer, Isaac P, Kelly, Jane X, Pou, Sovitj, Winter, Rolf W, Nilsen, Aaron, Vaidya, Akhil B, Riscoe, Michael K
Published in Antimicrobial agents and chemotherapy (01.08.2016)
Published in Antimicrobial agents and chemotherapy (01.08.2016)
Get full text
Journal Article
ELQ-300 prodrugs for enhanced delivery and single-dose cure of malaria
Miley, Galen P, Pou, Sovitj, Winter, Rolf, Nilsen, Aaron, Li, Yuexin, Kelly, Jane X, Stickles, Allison M, Mather, Michael W, Forquer, Isaac P, Pershing, April M, White, Karen, Shackleford, David, Saunders, Jessica, Chen, Gong, Ting, Li-Min, Kim, Kami, Zakharov, Lev N, Donini, Cristina, Burrows, Jeremy N, Vaidya, Akhil B, Charman, Susan A, Riscoe, Michael K
Published in Antimicrobial agents and chemotherapy (01.09.2015)
Published in Antimicrobial agents and chemotherapy (01.09.2015)
Get full text
Journal Article
Synthesis, Structure−Activity Relationship, and Mode-of-Action Studies of Antimalarial Reversed Chloroquine Compounds
Burgess, Steven J, Kelly, Jane X, Shomloo, Shawheen, Wittlin, Sergio, Brun, Reto, Liebmann, Katherine, Peyton, David H
Published in Journal of medicinal chemistry (09.09.2010)
Published in Journal of medicinal chemistry (09.09.2010)
Get full text
Journal Article
Depsipeptide Companeramides from a Panamanian Marine Cyanobacterium Associated with the Coibamide Producer
Vining, Oliver B, Medina, Rebecca A, Mitchell, Edward A, Videau, Patrick, Li, Dong, Serrill, Jeffrey D, Kelly, Jane X, Gerwick, William H, Proteau, Philip J, Ishmael, Jane E, McPhail, Kerry L
Published in Journal of natural products (Washington, D.C.) (27.03.2015)
Published in Journal of natural products (Washington, D.C.) (27.03.2015)
Get full text
Journal Article
Simplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based Drugs
Gunsaru, Bornface, Burgess, Steven J, Morrill, Westin, Kelly, Jane X, Shomloo, Shawheen, Smilkstein, Martin J, Liebman, Katherine, Peyton, David H
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Get full text
Journal Article
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials
Kancharla, Papireddy, Dodean, Rozalia A., Li, Yuexin, Pou, Sovitj, Pybus, Brandon, Melendez, Victor, Read, Lisa, Bane, Charles E., Vesely, Brian, Kreishman-Deitrick, Mara, Black, Chad, Li, Qigui, Sciotti, Richard J., Olmeda, Raul, Luong, Thu-Lan, Gaona, Heather, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Caridha, Diana, Xie, Lisa, Chau Vuong, Zeng, Qiang, Zhang, Jing, Zhang, Ping, Lin, Hsiuling, Butler, Kirk, Roncal, Norma, Gaynor-Ohnstad, Lacy, Leed, Susan E., Nolan, Christina, Ceja, Frida G., Rasmussen, Stephanie A., Tumwebaze, Patrick K., Rosenthal, Philip J., Mu, Jianbing, Bayles, Brett R., Cooper, Roland A., Reynolds, Kevin A., Smilkstein, Martin J., Riscoe, Michael K., Kelly, Jane X.
Published in Journal of medicinal chemistry (11.06.2020)
Published in Journal of medicinal chemistry (11.06.2020)
Get full text
Journal Article
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials
Dodean, Rozalia A, Kancharla, Papireddy, Li, Yuexin, Melendez, Victor, Read, Lisa, Bane, Charles E, Vesely, Brian, Kreishman-Deitrick, Mara, Black, Chad, Li, Qigui, Sciotti, Richard J, Olmeda, Raul, Luong, Thu-Lan, Gaona, Heather, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Caridha, Diana, Xie, Lisa, Vuong, Chau, Zeng, Qiang, Zhang, Jing, Zhang, Ping, Lin, Hsiuling, Butler, Kirk, Roncal, Norma, Gaynor-Ohnstad, Lacy, Leed, Susan E, Nolan, Christina, Huezo, Stephanie J, Rasmussen, Stephanie A, Stephens, Melissa T, Tan, John C, Cooper, Roland A, Smilkstein, Martin J, Pou, Sovitj, Winter, Rolf W, Riscoe, Michael K, Kelly, Jane X
Published in Journal of medicinal chemistry (11.04.2019)
Published in Journal of medicinal chemistry (11.04.2019)
Get full text
Journal Article
Interrogating the Tailoring Steps of Pactamycin Biosynthesis and Accessing New Pactamycin Analogues
Abugrain, Mostafa E., Lu, Wanli, Li, Yuexin, Serrill, Jeffrey D., Brumsted, Corey J., Osborn, Andrew R., Alani, Adam, Ishmael, Jane E., Kelly, Jane X., Mahmud, Taifo
Published in Chembiochem : a European journal of chemical biology (02.09.2016)
Published in Chembiochem : a European journal of chemical biology (02.09.2016)
Get full text
Journal Article
3‑Position Biaryl Endochin-like Quinolones with Enhanced Antimalarial Performance
Pou, Sovitj, Winter, Rolf W., Dodean, Rozalia A., Liebman, Katherine, Li, Yuexin, Mather, Michael W., Nepal, Binod, Nilsen, Aaron, Handford, Mason J., Riscoe, Teresa M., Laxson, Sydney, Kirtley, Payton J., Aleshnick, Maya, Zakharov, Lev N., Kelly, Jane X., Smilkstein, Martin J., Wilder, Brandon K., Kortagere, Sandhya, Vaidya, Akhil B., Alday, P. Holland, Doggett, J. Stone, Riscoe, Michael K.
Published in ACS infectious diseases (12.07.2024)
Published in ACS infectious diseases (12.07.2024)
Get full text
Journal Article