Recent advances in the development of 1,8-naphthalimide based DNA targeting binders, anticancer and fluorescent cellular imaging agents
Banerjee, Swagata, Veale, Emma B, Phelan, Caroline M, Murphy, Samantha A, Tocci, Gillian M, Gillespie, Lisa J, Frimannsson, Daniel O, Kelly, John M, Gunnlaugsson, Thorfinnur
Published in Chemical Society reviews (01.01.2013)
Published in Chemical Society reviews (01.01.2013)
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Challenges in Chagas Disease Drug Development
Francisco, Amanda F, Jayawardhana, Shiromani, Olmo, Francisco, Lewis, Michael D, Wilkinson, Shane R, Taylor, Martin C, Kelly, John M
Published in Molecules (Basel, Switzerland) (17.06.2020)
Published in Molecules (Basel, Switzerland) (17.06.2020)
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Intracellular DNA replication and differentiation of Trypanosoma cruzi is asynchronous within individual host cells in vivo at all stages of infection
Taylor, Martin C, Ward, Alexander, Olmo, Francisco, Jayawardhana, Shiromani, Francisco, Amanda F, Lewis, Michael D, Kelly, John M
Published in PLoS neglected tropical diseases (01.03.2020)
Published in PLoS neglected tropical diseases (01.03.2020)
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Enteric nervous system regeneration and functional cure of experimental digestive Chagas disease with trypanocidal chemotherapy
Khan, Archie A, Langston, Harry C, Walsh, Louis, Roscoe, Rebecca, Jayawardhana, Shiromani, Francisco, Amanda Fortes, Taylor, Martin C, McCann, Conor J, Kelly, John M, Lewis, Michael D
Published in Nature communications (23.05.2024)
Published in Nature communications (23.05.2024)
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From Ag Nanoprisms to Triangular AuAg Nanoboxes
Aherne, Damian, Gara, Matthew, Kelly, John M., Gun'ko, Yurii K.
Published in Advanced functional materials (23.04.2010)
Published in Advanced functional materials (23.04.2010)
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Local association of Trypanosoma cruzi chronic infection foci and enteric neuropathic lesions at the tissue micro-domain scale
Khan, Archie A, Langston, Harry C, Costa, Fernanda C, Olmo, Francisco, Taylor, Martin C, McCann, Conor J, Kelly, John M, Lewis, Michael D
Published in PLoS pathogens (23.08.2021)
Published in PLoS pathogens (23.08.2021)
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Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand
Hall, James P, O’Sullivan, Kyra, Naseer, Abeer, Smith, Jayden A, Kelly, John M, Cardin, Christine J
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2011)
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Benznidazole treatment leads to DNA damage in Trypanosoma cruzi and the persistence of rare widely dispersed non-replicative amastigotes in mice
Jayawardhana, Shiromani, Ward, Alexander I, Francisco, Amanda F, Lewis, Michael D, Taylor, Martin C, Kelly, John M, Olmo, Francisco
Published in PLoS pathogens (13.11.2023)
Published in PLoS pathogens (13.11.2023)
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Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage
Francisco, Amanda Fortes, Jayawardhana, Shiromani, Lewis, Michael D, White, Karen L, Shackleford, David M, Chen, Gong, Saunders, Jessica, Osuna-Cabello, Maria, Read, Kevin D, Charman, Susan A, Chatelain, Eric, Kelly, John M
Published in Scientific reports (17.10.2016)
Published in Scientific reports (17.10.2016)
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Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers for monitoring parasitological cure
Francisco, Amanda Fortes, Saade, Ursula, Jayawardhana, Shiromani, Pottel, Hans, Scandale, Ivan, Chatelain, Eric, Liehl, Peter, Kelly, John M, Zrein, Maan
Published in PLoS neglected tropical diseases (03.10.2022)
Published in PLoS neglected tropical diseases (03.10.2022)
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Dynamics of Trypanosoma cruzi infection in hamsters and novel association with progressive motor dysfunction
Langston, Harry, Fortes Francisco, Amanda, Doidge, Ciaran, Roberts, Chrissy H, Khan, Archie A, Jayawardhana, Shiromani, Taylor, Martin C, Kelly, John M, Lewis, Michael D
Published in PLoS neglected tropical diseases (21.06.2024)
Published in PLoS neglected tropical diseases (21.06.2024)
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Journal Article
Imaging the development of chronic Chagas disease after oral transmission
Lewis, Michael D, Francisco, Amanda F, Jayawardhana, Shiromani, Langston, Harry, Taylor, Martin C, Kelly, John M
Published in Scientific reports (26.07.2018)
Published in Scientific reports (26.07.2018)
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Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy
Hall, James P, Poynton, Fergus E, Keane, Páraic M, Gurung, Sarah P, Brazier, John A, Cardin, David J, Winter, Graeme, Gunnlaugsson, Thorfinnur, Sazanovich, Igor V, Towrie, Michael, Cardin, Christine J, Kelly, John M, Quinn, Susan J
Published in Nature chemistry (01.12.2015)
Published in Nature chemistry (01.12.2015)
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