Correction to Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection
Link, John O, Taylor, James G, Xu, Lianhong, Mitchell, Michael, Guo, Hongyan, Liu, Hongtao, Kato, Darryl, Kirschberg, Thorsten, Sun, Jianyu, Squires, Neil, Parrish, Jay, Kellar, Terry, Yang, Zheng-Yu, Yang, Chris, Matles, Mike, Wang, Yujin, Wang, Kelly, Cheng, Guofeng, Tian, Yang, Mogalian, Erik, Mondou, Elsa, Cornpropst, Melanie, Perry, Jason, Desai, Manoj C
Published in Journal of medicinal chemistry (25.08.2016)
Published in Journal of medicinal chemistry (25.08.2016)
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Journal Article
Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection
Link, John O., Taylor, James G., Xu, Lianhong, Mitchell, Michael, Guo, Hongyan, Liu, Hongtao, Kato, Darryl, Kirschberg, Thorsten, Sun, Jianyu, Squires, Neil, Parrish, Jay, Keller, Terry, Yang, Zheng-Yu, Yang, Chris, Matles, Mike, Wang, Yujin, Wang, Kelly, Cheng, Guofeng, Tian, Yang, Mogalian, Erik, Mondou, Elsa, Cornpropst, Melanie, Perry, Jason, Desai, Manoj C.
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N‑(1H‑Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12)
Patel, Snahel, Harris, Seth F, Gibbons, Paul, Deshmukh, Gauri, Gustafson, Amy, Kellar, Terry, Lin, Han, Liu, Xingrong, Liu, Yanzhou, Liu, Yichin, Ma, Changyou, Scearce-Levie, Kimberly, Ghosh, Arundhati Sengupta, Shin, Young G, Solanoy, Hilda, Wang, Jian, Wang, Bei, Yin, Jianping, Siu, Michael, Lewcock, Joseph W
Published in Journal of medicinal chemistry (22.10.2015)
Published in Journal of medicinal chemistry (22.10.2015)
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Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling
Zak, Mark, Hanan, Emily J., Lupardus, Patrick, Brown, David G., Robinson, Colin, Siu, Michael, Lyssikatos, Joseph P., Romero, F. Anthony, Zhao, Guiling, Kellar, Terry, Mendonca, Rohan, Ray, Nicholas C., Goodacre, Simon C., Crackett, Peter H., McLean, Neville, Hurley, Christopher A., Yuen, Po-wai, Cheng, Yun-Xing, Liu, Xiongcai, Liimatta, Marya, Kohli, Pawan Bir, Nonomiya, Jim, Salmon, Gary, Buckley, Gerry, Lloyd, Julia, Gibbons, Paul, Ghilardi, Nico, Kenny, Jane R., Johnson, Adam
Published in Bioorganic & medicinal chemistry letters (15.06.2019)
Published in Bioorganic & medicinal chemistry letters (15.06.2019)
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BIHETEROARYL COMPOUNDS AND USES THEREOF
ESTRADA ANTHONY, KELLAR TERRY, DONG LITING, LIU WEN, HUESTIS MALCOLM, MA CHANGYOU, SIU MICHAEL, OLIVERO ALAN, PATEL SNAHEL, CHEN KEVIN X, SHORE DANIEL, LYSSIKATOS JOSEPH P, GIBBONS PAUL
Year of Publication 13.03.2018
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Year of Publication 13.03.2018
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ANTIVIRAL COMPOUNDS
SQUIRES NEIL, WATKINS WILLIAM J, CHO AESOP, DESAI MANOJ C, BACON ELIZABETH M, KRYGOWSKI EVAN S, SCHROEDER SCOTT D, LIU QI, TSE WINSTON C, SAUGIER JOSEPH H, XU LIANHONG, LAZERWITH SCOTT E, KATO DARRYL, PYUN HYUNG JUNG, MISH MICHAEL R, TRENKLE JAMES D, CLARKE MICHAEL O'NEIL HANRAHAN, PHILLIPS BARTON W, GUO HONGYAN, KELLAR TERRY, SUN JIANYU, KIRSCHBERG THORSTEN A, LINK JOHN O, COTTELL JEROMY J, VIVIAN RANDALL W, CANALES EDA, TAYLOR JAMES, MACKMAN RICHARD, LIU HONGTAO, CHOU CHIEN HUNG, VENKATARAMANI CHANDRASEKAR, MITCHELL MICHAEL L, JIN HAOLUN, METOBO SAMUEL E, YANG ZHENG YU, PARRISH JAY P, KIM CHOUNG U, MCFADDEN RYAN, GRAUPE MICHAEL, SHENG XIAONING, HALCOMB RANDALL L
Year of Publication 31.01.2020
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Year of Publication 31.01.2020
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ANTIVIRAL COMPOUNDS
SQUIRES NEIL, WATKINS WILLIAM J, CHO AESOP, DESAI MANOJ C, BACON ELIZABETH M, KRYGOWSKI EVAN S, SCHROEDER SCOTT D, LIU QI, TSE WINSTON C, SAUGIER JOSEPH H, XU LIANHONG, LAZERWITH SCOTT E, KATO DARRYL, PYUN HYUNG JUNG, MISH MICHAEL R, TRENKLE JAMES D, CLARKE MICHAEL O'NEIL HANRAHAN, PHILLIPS BARTON W, GUO HONGYAN, KELLAR TERRY, SUN JIANYU, KIRSCHBERG THORSTEN A, LINK JOHN O, COTTELL JEROMY J, VIVIAN RANDALL W, CANALES EDA, TAYLOR JAMES, MACKMAN RICHARD, LIU HONGTAO, CHOU CHIEN HUNG, VENKATARAMANI CHANDRASEKAR, MITCHELL MICHAEL L, JIN HAOLUN, METOBO SAMUEL E, YANG ZHENG YU, PARRISH JAY P, KIM CHOUNG U, MCFADDEN RYAN, GRAUPE MICHAEL, SHENG XIAONING, HALCOMB RANDALL L
Year of Publication 20.03.2019
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Year of Publication 20.03.2019
Patent
ANTIVIRAL COMPOUNDS
SQUIRES NEIL, WATKINS WILLIAM J, CHO AESOP, DESAI MANOJ C, BACON ELIZABETH M, KRYGOWSKI EVAN S, SCHROEDER SCOTT D, LIU QI, TSE WINSTON C, SAUGIER JOSEPH H, XU LIANHONG, LAZERWITH SCOTT E, KATO DARRYL, PYUN HYUNG JUNG, MISH MICHAEL R, TRENKLE JAMES D, CLARKE MICHAEL O'NEIL HANRAHAN, PHILLIPS BARTON W, GUO HONGYAN, KELLAR TERRY, SUN JIANYU, KIRSCHBERG THORSTEN A, LINK JOHN O, COTTELL JEROMY J, VIVIAN RANDALL W, CANALES EDA, TAYLOR JAMES, MACKMAN RICHARD, LIU HONGTAO, CHOU CHIEN HUNG, VENKATARAMANI CHANDRASEKAR, MITCHELL MICHAEL L, JIN HAOLUN, METOBO SAMUEL E, YANG ZHENG YU, PARRISH JAY P, KIM CHOUNG U, MCFADDEN RYAN, GRAUPE MICHAEL, SHENG XIAONING, HALCOMB RANDALL L
Year of Publication 15.03.2018
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Year of Publication 15.03.2018
Patent
BIHETEROARYL COMPOUNDS AND USES THEREOF
ESTRADA ANTHONY, KELLAR TERRY, DONG LITING, LIU WEN, HUESTIS MALCOLM, MA CHANGYOU, SIU MICHAEL, OLIVERO ALAN, PATEL SNAHEL, CHEN KEVIN X, SHORE DANIEL, LYSSIKATOS JOSEPH P, GIBBONS PAUL
Year of Publication 08.01.2016
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Year of Publication 08.01.2016
Patent