Cystathionine β-Synthase in Physiology and Cancer
Pearson, Richard B., Chan, Keefe T., Blake, Shaun, Zhu, Haoran, Kang, Jian
Published in BioMed research international (01.01.2018)
Published in BioMed research international (01.01.2018)
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Regulation of Adhesion Dynamics by Calpain-mediated Proteolysis of Focal Adhesion Kinase (FAK)
Chan, Keefe T., Bennin, David A., Huttenlocher, Anna
Published in The Journal of biological chemistry (09.04.2010)
Published in The Journal of biological chemistry (09.04.2010)
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To bud or not to bud: the RET perspective in CAKUT
Davis, T. Keefe, Hoshi, Masato, Jain, Sanjay
Published in Pediatric nephrology (Berlin, West) (01.04.2014)
Published in Pediatric nephrology (Berlin, West) (01.04.2014)
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FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion
Chan, Keefe T, Cortesio, Christa L, Huttenlocher, Anna
Published in The Journal of cell biology (20.04.2009)
Published in The Journal of cell biology (20.04.2009)
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Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma
AbuHammad, Shatha, Cullinane, Carleen, Martin, Claire, Bacolas, Zoe, Ward, Teresa, Chen, Huiqin, Slater, Alison, Ardley, Kerry, Kirby, Laura, Chan, Keefe T., Brajanovski, Natalie, Smith, Lorey K., Rao, Aparna D., Lelliott, Emily J., Kleinschmidt, Margarete, Vergara, Ismael A., Papenfuss, Anthony T., Lau, Peter, Ghosh, Prerana, Haupt, Sue, Haupt, Ygal, Sanij, Elaine, Poortinga, Gretchen, Pearson, Richard B., Falk, Hendrik, Curtis, David J., Stupple, Paul, Devlin, Mark, Street, Ian, Davies, Michael A., McArthur, Grant A., Sheppard, Karen E.
Published in Proceedings of the National Academy of Sciences - PNAS (03.09.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (03.09.2019)
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Oncogene-induced senescence: From biology to therapy
Zhu, Haoran, Blake, Shaun, Kusuma, Frances K, Pearson, Richard B, Kang, Jian, Chan, Keefe T
Published in Mechanisms of ageing and development (01.04.2020)
Published in Mechanisms of ageing and development (01.04.2020)
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CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer
Sanij, Elaine, Hannan, Katherine M., Xuan, Jiachen, Yan, Shunfei, Ahern, Jessica E., Trigos, Anna S., Brajanovski, Natalie, Son, Jinbae, Chan, Keefe T., Kondrashova, Olga, Lieschke, Elizabeth, Wakefield, Matthew J., Frank, Daniel, Ellis, Sarah, Cullinane, Carleen, Kang, Jian, Poortinga, Gretchen, Nag, Purba, Deans, Andrew J., Khanna, Kum Kum, Mileshkin, Linda, McArthur, Grant A., Soong, John, Berns, Els M. J. J., Hannan, Ross D., Scott, Clare L., Sheppard, Karen E., Pearson, Richard B.
Published in Nature communications (26.05.2020)
Published in Nature communications (26.05.2020)
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A functional genetic screen defines the AKT-induced senescence signaling network
Chan, Keefe T., Blake, Shaun, Zhu, Haoran, Kang, Jian, Trigos, Anna S., Madhamshettiwar, Piyush B., Diesch, Jeannine, Paavolainen, Lassi, Horvath, Peter, Hannan, Ross D., George, Amee J., Sanij, Elaine, Hannan, Katherine M., Simpson, Kaylene J., Pearson, Richard B.
Published in Cell death and differentiation (01.02.2020)
Published in Cell death and differentiation (01.02.2020)
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A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity
Ling, Xiang, Cao, Shousong, Cheng, Qiuying, Keefe, James T, Rustum, Youcef M, Li, Fengzhi
Published in PloS one (19.09.2012)
Published in PloS one (19.09.2012)
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LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma
Liu, Wenjin, Monahan, Kimberly B., Pfefferle, Adam D., Shimamura, Takeshi, Sorrentino, Jessica, Chan, Keefe T., Roadcap, David W., Ollila, David W., Thomas, Nancy E., Castrillon, Diego H., Miller, C. Ryan, Perou, Charles M., Wong, Kwok-Kin, Bear, James E., Sharpless, Norman E.
Published in Cancer cell (12.06.2012)
Published in Cancer cell (12.06.2012)
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Variability in Culture-Negative Peritonitis Rates in Pediatric Peritoneal Dialysis Programs in the United States
Davis, T Keefe, Bryant, Kristina A, Rodean, Jonathan, Richardson, Troy, Selvarangan, Rangaraj, Qin, Xuan, Neu, Alicia, Warady, Bradley A
Published in Clinical journal of the American Society of Nephrology (08.02.2021)
Published in Clinical journal of the American Society of Nephrology (08.02.2021)
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INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors
Dietrich, Catherine, Trub, Alec, Ahn, Antonio, Taylor, Michael, Ambani, Krutika, Chan, Keefe T, Lu, Kun-Hui, Mahendra, Christabella A, Blyth, Catherine, Coulson, Rhiannon, Ramm, Susanne, Watt, April C, Matsa, Sunil Kumar, Bisi, John, Strum, Jay, Roberts, Patrick, Goel, Shom
Published in Cancer discovery (01.03.2024)
Published in Cancer discovery (01.03.2024)
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Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling
Quin, Jaclyn, Chan, Keefe T, Devlin, Jennifer R, Cameron, Donald P, Diesch, Jeannine, Cullinane, Carleen, Ahern, Jessica, Khot, Amit, Hein, Nadine, George, Amee J, Hannan, Katherine M, Poortinga, Gretchen, Sheppard, Karen E, Khanna, Kum Kum, Johnstone, Ricky W, Drygin, Denis, McArthur, Grant A, Pearson, Richard B, Sanij, Elaine, Hannan, Ross D
Published in Oncotarget (02.08.2016)
Published in Oncotarget (02.08.2016)
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The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer
Yan, Shunfei, Xuan, Jiachen, Brajanovski, Natalie, Tancock, Madeleine R. C., Madhamshettiwar, Piyush B., Simpson, Kaylene J., Ellis, Sarah, Kang, Jian, Cullinane, Carleen, Sheppard, Karen E., Hannan, Katherine M., Hannan, Ross D., Sanij, Elaine, Pearson, Richard B., Chan, Keefe T.
Published in British journal of cancer (02.02.2021)
Published in British journal of cancer (02.02.2021)
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Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings
Pelletier, Jonathan H., Kumar, Karan R., Engen, Rachel, Bensimhon, Adam, Varner, Jennifer D., Rheault, Michelle N., Srivastava, Tarak, Straatmann, Caroline, Silva, Cynthia, Davis, T. Keefe, Wenderfer, Scott E., Gibson, Keisha, Selewski, David, Barcia, John, Weng, Patricia, Licht, Christoph, Jawa, Natasha, Kallash, Mahmoud, Foreman, John W., Wigfall, Delbert R., Chua, Annabelle N., Chambers, Eileen, Hornik, Christoph P., Brewer, Eileen D., Nagaraj, Shashi K., Greenbaum, Larry A., Gbadegesin, Rasheed A.
Published in Pediatric nephrology (Berlin, West) (01.10.2018)
Published in Pediatric nephrology (Berlin, West) (01.10.2018)
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Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation
Zhu, Haoran, Chan, Keefe T, Huang, Xinran, Cerra, Carmelo, Blake, Shaun, Trigos, Anna S, Anderson, Dovile, Creek, Darren J, De Souza, David P, Wang, Xi, Fu, Caiyun, Jana, Metta, Sanij, Elaine, Pearson, Richard B, Kang, Jian
Published in eLife (27.06.2022)
Published in eLife (27.06.2022)
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Implementation of a standardized clinical pathway in a dedicated posterior urethral valves clinic: short-term outcomes
Rickard, Mandy, Lorenzo, Armando J., Richter, Juliane, Brownrigg, Natasha, Kim, Jin K., Chua, Michael, Goraya, Noreen, Khondker, Adree, Yadav, Priyank, Keefe, Daniel T., Shinar, Shiri, Dos Santos, Joana
Published in Pediatric nephrology (Berlin, West) (01.11.2023)
Published in Pediatric nephrology (Berlin, West) (01.11.2023)
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