Vitamin D antagonist, TEI-9647, inhibits osteoclast formation induced by 1α, 25-dihydroxyvitamin D3 from pagetic bone marrow cells
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Published in Journal of steroid biochemistry and molecular biology (01.05.2004)
Published in Journal of steroid biochemistry and molecular biology (01.05.2004)
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STUDIES ON THE SYNTHESIS AND METABOLISM OF 14-epi-2 alpha-(3-HYDROXYPROPYL)-19-NORVITAMIN D-3 AND ITS 2 beta-ISOMER
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Saito, N, Saito, H, Anzai, M, Yoshida, A, Fujishima, T, Takenouchi, K, Miura, D, Ishizuka, S, Takayama, H, Kittaka, A
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Published in Organic letters (11.12.2003)
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SYNTHESIS AND BIOLOGICAL ACTIVITIES OF VDR ANTAGONISTS; 25-MODIFIED 1 alpha,25-DIHYDROXYVITAMIN D-3-26,23-LACTAM (DLAM) DERIVATIVES
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Further synthetic and biological studies on vitamin D hormone antagonists based on C24-alkylation and C2alpha-functionalization of 25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactones
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Published in Journal of medicinal chemistry (30.11.2006)
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24,24-Dimethylvitamin D 3-26,23-lactones and their 2α-functionalized analogues as highly potent VDR antagonists
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1alpha,25-Dihydroxyvitamin D(3)-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells
Ishizuka, Seiichi, Kurihara, Noriyoshi, Hiruma, Yuko, Miura, Daishiro, Namekawa, Jun-ichi, Tamura, Azusa, Kato-Nakamura, Yuko, Nakano, Yusuke, Takenouchi, Kazuya, Hashimoto, Yuichi, Nagasawa, Kazuo, Roodman, G David
Published in The Journal of steroid biochemistry and molecular biology (01.06.2008)
Published in The Journal of steroid biochemistry and molecular biology (01.06.2008)
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1 alpha ,25-Dihydroxyvitamin D sub(3)-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells
Ishizuka, Seiichi, Kurihara, Noriyoshi, Hiruma, Yuko, Miura, Daishiro, Namekawa, Jun-Ichi, Tamura, Azusa, Kato-Nakamura, Yuko, Nakano, Yusuke, Takenouchi, Kazuya, Hashimoto, Yuichi, Nagasawa, Kazuo, Roodman, GDavid
Published in The Journal of steroid biochemistry and molecular biology (01.06.2008)
Published in The Journal of steroid biochemistry and molecular biology (01.06.2008)
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Synthesis and structure–activity relationships of TEI-9647 derivatives as Vitamin D 3 antagonists
Takenouchi, Kazuya, Sogawa, Ryo, Manabe, Kenji, Saitoh, Hiroshi, Gao, Qingzhi, Miura, Daishiro, Ishizuka, Seiichi
Published in The Journal of steroid biochemistry and molecular biology (01.05.2004)
Published in The Journal of steroid biochemistry and molecular biology (01.05.2004)
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Vitamin D antagonist, TEI-9647, inhibits osteoclast formation induced by 1α,25-dihydroxyvitamin D 3 from pagetic bone marrow cells
Ishizuka, Seiichi, Kurihara, Noriyoshi, Miura, Daishiro, Takenouchi, Kazuya, Cornish, Jillian, Cundy, Tim, Reddy, Sakamuri V., Roodman, G.David
Published in The Journal of steroid biochemistry and molecular biology (01.05.2004)
Published in The Journal of steroid biochemistry and molecular biology (01.05.2004)
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1α,25-Dihydroxyvitamin D 3-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells
Ishizuka, Seiichi, Kurihara, Noriyoshi, Hiruma, Yuko, Miura, Daishiro, Namekawa, Jun-ichi, Tamura, Azusa, Kato-Nakamura, Yuko, Nakano, Yusuke, Takenouchi, Kazuya, Hashimoto, Yuichi, Nagasawa, Kazuo, Roodman, G. David
Published in The Journal of steroid biochemistry and molecular biology (2008)
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The Difference between 14-Epi-previtamin D3 and 14-Epi-19-norprevitamin D3: Their Synthesis and Binding Affinity for Human VDR
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Published in Anticancer research (2012)
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Practical synthesis and evaluation of the biological activities of 1alpha,25-dihydroxyvitamin D3 antagonists, 1alpha,25-dihydroxyvitamin D3-26,23-lactams. Designed on the basis of the helix 12-folding inhibition hypothesis
Nakano, Yusuke, Kato, Yuko, Imai, Keisuke, Ochiai, Eiji, Namekawa, Jun-Ichi, Ishizuka, Seiichi, Takenouchi, Kazuya, Tanatani, Aya, Hashimoto, Yuichi, Nagasawa, Kazuo
Published in Journal of medicinal chemistry (20.04.2006)
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Molecular mechanism of the vitamin D antagonistic actions of (23S)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone depends on the primary structure of the carboxyl-terminal region of the vitamin d receptor
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Published in Molecular endocrinology (Baltimore, Md.) (01.05.2005)
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Synthesis and biological activities of 1α,4α,25- and 1α,4β,25-trihydroxyvitamin D(3) and their metabolism by human CYP24A1 and UDP-glucuronosyltransferase
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Published in Chemical & pharmaceutical bulletin (2012)
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Published in Chemical & pharmaceutical bulletin (2012)
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Synthesis of 2beta-substituted-14-epi-previtamin D3 and testing of its genomic activity
Sawada, Daisuke, Tsukuda, Yuya, Saito, Hiroshi, Takagi, Ken-ichiro, Ochiai, Eiji, Ishizuka, Seiichi, Takenouchi, Kazuya, Kittaka, Atsushi
Published in The Journal of steroid biochemistry and molecular biology (01.07.2010)
Published in The Journal of steroid biochemistry and molecular biology (01.07.2010)
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C15-functionalized 16-Ene-1α,25-dihydroxyvitamin D3 is a New Vitamin D Analog with Unique Biological Properties
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Published in Anticancer research (2012)
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Dramatic enhancement of antagonistic activity on vitamin D receptor: a double functionalization of 1alpha-hydroxyvitamin D3 26,23-lactones
Saito, Nozomi, Saito, Hiroshi, Anzai, Miyuki, Yoshida, Akihiro, Fujishima, Toshie, Takenouchi, Kazuya, Miura, Daishiro, Ishizuka, Seiichi, Takayama, Hiroaki, Kittaka, Atsushi
Published in Organic letters (11.12.2003)
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Published in Organic letters (11.12.2003)
Journal Article
Vitamin D antagonist, TEI-9647, inhibits osteoclast formation induced by 1alpha,25-dihydroxyvitamin D3 from pagetic bone marrow cells
Ishizuka, Seiichi, Kurihara, Noriyoshi, Miura, Daishiro, Takenouchi, Kazuya, Cornish, Jillian, Cundy, Tim, Reddy, Sakamuri V, Roodman, G David
Published in The Journal of steroid biochemistry and molecular biology (01.05.2004)
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Published in The Journal of steroid biochemistry and molecular biology (01.05.2004)
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