K858, a Novel Inhibitor of Mitotic Kinesin Eg5 and Antitumor Agent, Induces Cell Death in Cancer Cells
NAKAI, Ryuichiro, IIDA, Shin-Ichi, AKINAGA, Shiro, MURAKATA, Chikara, HONDA, Shinobu, NITTA, Masayuki, SAYA, Hideyuki, YAMASHITA, Yoshinori, TAKAHASHI, Takeshi, TSUJITA, Tetsuya, OKAMOTO, Seiho, TAKADA, Chie, AKASAKA, Kazuhito, ICHIKAWA, Shunji, ISHIDA, Hiroyuki, KUSAKA, Hideaki
Published in Cancer research (Chicago, Ill.) (01.05.2009)
Published in Cancer research (Chicago, Ill.) (01.05.2009)
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Journal Article
Cysteine-rich Region of Raf-1 Interacts with Activator Domain of Post-translationally Modified Ha-Ras (∗)
Hu, Chang-Deng, Kariya, Ken-ichi, Tamada, Masako, Akasaka, Kazuhito, Shirouzu, Mikako, Yokoyama, Shigeyuki, Kataoka, Tohru
Published in The Journal of biological chemistry (22.12.1995)
Published in The Journal of biological chemistry (22.12.1995)
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Journal Article
Differential Structural Requirements for Interaction of Ras Protein with Its Distinct Downstream Effectors (∗)
Akasaka, Kazuhito, Tamada, Masako, Wang, Feng, Kariya, Ken-ichi, Shima, Fumi, Kikuchi, Akira, Yamamoto, Masayuki, Shirouzu, Mikako, Yokoyama, Shigeyuki, Kataoka, Tohru
Published in The Journal of biological chemistry (08.03.1996)
Published in The Journal of biological chemistry (08.03.1996)
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Journal Article
Halohydrin and Oxime Derivatives of Radicicol: Synthesis and Antitumor Activities
Agatsuma, Tsutomu, Ogawa, Harumi, Akasaka, Kazuhito, Asai, Akira, Yamashita, Yoshinori, Mizukami, Tamio, Akinaga, Shiro, Saitoh, Yutaka
Published in Bioorganic & medicinal chemistry (01.11.2002)
Published in Bioorganic & medicinal chemistry (01.11.2002)
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Journal Article
KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules
SOGA, S, NECKERS, L. M, AKINAGA, S, SCHULTE, T. W, SHIOTSU, Y, AKASAKA, K, NARUMI, H, AGATSUMA, T, IKUINA, Y, MURAKATA, C, TAMAOKI, T
Published in Cancer research (Chicago, Ill.) (15.06.1999)
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Published in Cancer research (Chicago, Ill.) (15.06.1999)
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Identification of Ras Farnesyltransferase Inhibitors by Microbial Screening
Hara, Mitsunobu, Akasaka, Kazuhito, Akinaga, Shiro, Okabe, Masami, Nakano, Hirofumi, Gomez, Ruben, Wood, Douglas, Uh, Misook, Tamanoi, Fuyuhiko
Published in Proceedings of the National Academy of Sciences - PNAS (15.03.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (15.03.1993)
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Journal Article
Ras p21 proteins
Hirofumi Nakano, Mitsunobu Hara, Kazuhito Akasaka, Fuyuhiko Tamanoi
Published in Japanese Journal of Pharmacology (1994)
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Published in Japanese Journal of Pharmacology (1994)
Journal Article
Quantitative analysis of mutually competitive binding of human Raf-1 and yeast adenylyl cyclase to Ras proteins
MINATO, T, JUN WANG, AKASAKA, K, OKADA, T, SUZUKI, N, KATAOKA, T
Published in The Journal of biological chemistry (19.08.1994)
Published in The Journal of biological chemistry (19.08.1994)
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Journal Article
Molecular cloning, sequencing, and mapping of the gene encoding protease I and characterization of proteinase and proteinase-defective Escherichia coli mutants
ICHIHARA, S, MATSUBARA, Y, KATO, C, AKASAKA, K, MIZUSHIMA, S
Published in Journal of Bacteriology (01.02.1993)
Published in Journal of Bacteriology (01.02.1993)
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Journal Article
Inhibidor de cinesina mitótica
AKASAKA, KAZUHITO, KATO, KAZUHIKO, MURAKATA, CHIKARA, YAMASHITA, YOSHINORI, INO, YOJI, KITAMURA, YUSHI, NAKAI, RYUICHIRO
Year of Publication 06.02.2013
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Year of Publication 06.02.2013
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Mitotic kinesin inhibitor
AKASAKA, KAZUHITO, KATO, KAZUHIKO, MURAKATA, CHIKARA, YAMASHITA, YOSHINORI, INO, YOJI, KITAMURA, YUSHI, NAKAI, RYUICHIRO
Year of Publication 29.08.2012
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Year of Publication 29.08.2012
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MITOTIC KINESIN INHIBITOR M
AKASAKA, KAZUHITO, KATO, KAZUHIKO, MURAKATA, CHIKARA, YAMASHITA, YOSHINORI, INO, YOJI, KITAMURA, YUSHI, NAKAI, RYUICHIRO
Year of Publication 20.07.2012
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Year of Publication 20.07.2012
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Inhibidor de quinesina en etapa M
AKASAKA, KAZUHITO, KATO, KAZUHIKO, MURAKATA, CHIKARA, YAMASHITA, YOSHINORI, INO, YOJI, KITAMURA, YUSHI, NAKAI, RYUICHIRO
Year of Publication 28.03.2012
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Year of Publication 28.03.2012
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MITOTIC KINESIN INHIBITOR
AKASAKA, KAZUHITO, KATO, KAZUHIKO, MURAKATA, CHIKARA, YAMASHITA, YOSHINORI, INO, YOJI, KITAMURA, YUSHI, NAKAI, RYUICHIRO
Year of Publication 24.01.2012
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Year of Publication 24.01.2012
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M-STAGE-KINESIN-INHIBITOR
AKASAKA, KAZUHITO, KATO, KAZUHIKO, MURAKATA, CHIKARA, YAMASHITA, YOSHINORI, INO, YOJI, KITAMURA, YUSHI, NAKAI, RYUICHIRO
Year of Publication 15.12.2011
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Year of Publication 15.12.2011
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M-STAGE KINESIN INHIBITOR
AKASAKA, KAZUHITO, KATO, KAZUHIKO, MURAKATA, CHIKARA, YAMASHITA, YOSHINORI, INO, YOJI, KITAMURA, YUSHI, NAKAI, RYUICHIRO
Year of Publication 14.12.2011
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Year of Publication 14.12.2011
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Mitotic kinesin inhibitor
AKASAKA, KAZUHITO, KATO, KAZUHIKO, MURAKATA, CHIKARA, YAMASHITA, YOSHINORI, INO, YOJI, KITAMURA, YUSHI, NAKAI, RYUICHIRO
Year of Publication 01.06.2011
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Year of Publication 01.06.2011
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Mitotic Kinesin Inhibitor
INO YOJI, KITAMURA YUSHI, YAMASHITA YOSHINORI, MURAKATA CHIKARA, NAKAI RYUICHIRO, AKASAKA KAZUHITO, KATO KAZUHIKO
Year of Publication 06.01.2011
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Year of Publication 06.01.2011
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Mitotic kinesin inhibitor
CHIKARA MURAKATA, RYUICHIRO NAKAI, KAZUHITO AKASAKA, YUSHI KITAMURA, YOSHINORI YAMASHITA, KAZUHIKO KATO, YOJI INO
Year of Publication 18.03.2010
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Year of Publication 18.03.2010
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M-STAGE KINESIN INHIBITOR
MURAKATA, C, KATO, K, YAMASHITA, Y, AKASAKA, KAZUHITO, KITAMURA, YUSHI, INO, Y, NAKAI, R
Year of Publication 24.09.2008
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Year of Publication 24.09.2008
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