Inhibition of Endotoxin Response by E5564, a Novel Toll-Like Receptor 4-Directed Endotoxin Antagonist
Mullarkey, Maureen, Rose, Jeffrey R, Bristol, John, Kawata, Tsutomu, Kimura, Akufumi, Kobayashi, Seiichi, Przetak, Melinda, Chow, Jesse, Gusovsky, Fabian, Christ, William J, Rossignol, Daniel P
Published in The Journal of pharmacology and experimental therapeutics (01.03.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2003)
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Simultaneous Blocking of Human Toll-Like Receptors 2 and 4 Suppresses Myeloid Dendritic Cell Activation Induced by Mycobacterium bovis Bacillus Calmette-Guérin Peptidoglycan
UEHORI, Junji, MATSUMOTO, Misako, TSUJI, Shoutaro, AKAZAWA, Takashi, TAKEUCHI, Osamu, AKIRA, Shizuo, KAWATA, Tsutomu, AZUMA, Ichiro, TOYOSHIMA, Kumao, SEYA, Tsukasa
Published in Infection and Immunity (01.08.2003)
Published in Infection and Immunity (01.08.2003)
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Oral administration of the thrombin receptor antagonist E5555 (atopaxar) attenuates intimal thickening following balloon injury in rats
Kogushi, Motoji, Matsuoka, Toshiyuki, Kuramochi, Hiroko, Murakami, Kimiyo, Kawata, Tsutomu, Kimura, Akifumi, Chiba, Kenichi, Musha, Takashi, Suzuki, Shuichi, Kawahara, Tetsuya, Kajiwara, Akiharu, Hishinuma, Ieharu
Published in European journal of pharmacology (01.09.2011)
Published in European journal of pharmacology (01.09.2011)
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Suppression of Murine Endotoxin Response by E5531, a Novel Synthetic Lipid A Antagonist
KOBAYASHI, S, KAWATA, T, KIMURA, A, MIYAMOTO, K, KATAYAMA, K, YAMATSU, I, ROSSIGNOL, D. P, CHRIST, W. J, KISHI, Y
Published in Antimicrobial Agents and Chemotherapy (01.11.1998)
Published in Antimicrobial Agents and Chemotherapy (01.11.1998)
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The novel and orally active thrombin receptor antagonist E5555 (Atopaxar) inhibits arterial thrombosis without affecting bleeding time in guinea pigs
Kogushi, Motoji, Matsuoka, Toshiyuki, Kawata, Tsutomu, Kuramochi, Hiroko, Kawaguchi, Shinki, Murakami, Kimiyo, Hiyoshi, Hironobu, Suzuki, Shuichi, Kawahara, Tetsuya, Kajiwara, Akiharu, Hishinuma, Ieharu
Published in European journal of pharmacology (25.04.2011)
Published in European journal of pharmacology (25.04.2011)
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2-Alkynyl-8-aryl-9-methyladenines as Novel Adenosine Receptor Antagonists: Their Synthesis and Structure−Activity Relationships toward Hepatic Glucose Production Induced via Agonism of the A2B Receptor
Harada, Hitoshi, Asano, Osamu, Hoshino, Yorihisa, Yoshikawa, Seiji, Matsukura, Masayuki, Kabasawa, Yasuhiro, Niijima, Jun, Kotake, Yoshihiko, Watanabe, Nobuhisa, Kawata, Tsutomu, Inoue, Takashi, Horizoe, Tatsuo, Yasuda, Nobuyuki, Minami, Hiroe, Nagata, Kaya, Murakami, Manabu, Nagaoka, Junsaku, Kobayashi, Seiichi, Tanaka, Isao, Abe, Shinya
Published in Journal of medicinal chemistry (18.01.2001)
Published in Journal of medicinal chemistry (18.01.2001)
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Functional characterization of the adenosine receptor contributing to glycogenolysis and gluconeogenesis in rat hepatocytes
Yasuda, Nobuyuki, Inoue, Takashi, Horizoe, Tatsuo, Nagata, Kaya, Minami, Hiroe, Kawata, Tsutomu, Hoshino, Yorihisa, Harada, Hitoshi, Yoshikawa, Seiji, Asano, Osamu, Nagaoka, Junsaku, Murakami, Manabu, Abe, Shinya, Kobayashi, Seiichi, Tanaka, Isao
Published in European journal of pharmacology (17.01.2003)
Published in European journal of pharmacology (17.01.2003)
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2-alkynyl-8-aryladenines possessing an amide moiety : Their synthesis and structure-activity relationships of effects on hepatic glucose production induced via agonism of the A2B adenosine receptor
HARADA, Hitoshi, ASANO, Osamu, TANAKA, Isao, ABE, Shinya, KAWATA, Tsutomu, INOUE, Takashi, HORIZOE, Tatsuo, YASUDA, Nobuyuki, NAGATA, Kaya, MURAKAMI, Manabu, NAGAOKA, Junsaku, KOBAYASHI, Seiichi
Published in Bioorganic & medicinal chemistry (01.10.2001)
Published in Bioorganic & medicinal chemistry (01.10.2001)
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E5531, a synthetic non‐toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharide
Kawata, Tsutomu, Bristol, John R, Rossignol, Daniel P, Rose, Jeffrey R, Kobayashi, Seiichi, Yokohama, Hiromitsu, Ishibashi, Akira, Christ, William J, Katayama, Koichi, Yamatsu, Isao, Kishi, Yoshito
Published in British journal of pharmacology (01.06.1999)
Published in British journal of pharmacology (01.06.1999)
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Simultaneous Blocking of Human Toll-Like Receptors 2 and 4 Suppresses Myeloid Dendritic Cell Activation Induced by Mycobacterium bovis Bacillus Calmette-Guérin Peptidoglycan
Uehori, Junji, Matsumoto, Misako, Tsuji, Shoutaro, Akazawa, Takashi, Takeuchi, Osamu, Akira, Shizuo, Kawata, Tsutomu, Azuma, Ichiro, Toyoshima, Kumao, Seya, Tsukasa
Published in Infection and immunity (01.08.2003)
Published in Infection and immunity (01.08.2003)
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Journal Article
1102-48 Inhibitory effect of E5555, an orally active thrombin receptor antagonist, on intimal hyperplasia following balloon injury
Matsuoka, Toshiyuki, Kogushi, Motoji, Kawata, Tsutomu, Kimura, Akifumi, Chiba, Ken-ichi, Musha, Takashi, Kobayashi, Hiroko, Kawahara, Tetsuya, Suzuki, Shuichi, Kajiwara, Akiharu, Hishinuma, Ieharu
Published in Journal of the American College of Cardiology (03.03.2004)
Published in Journal of the American College of Cardiology (03.03.2004)
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Characteristics of Viologen Derivatives for Electrochromic Display
Kawata, Tsutomu, Yamamoto, Motokazu, Yamana, Masao, Tajima, Moritaka, Nakano, Tomoyasu
Published in Japanese Journal of Applied Physics (01.01.1975)
Published in Japanese Journal of Applied Physics (01.01.1975)
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