Role of Rho in Salt-Sensitive Hypertension
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Published in International journal of molecular sciences (15.03.2021)
Published in International journal of molecular sciences (15.03.2021)
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Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency
Kawarazaki, Wakako, Mizuno, Risuke, Nishimoto, Mitsuhiro, Ayuzawa, Nobuhiro, Hirohama, Daigoro, Ueda, Kohei, Kawakami-Mori, Fumiko, Oba, Shigeyoshi, Marumo, Takeshi, Fujita, Toshiro
Published in The Journal of clinical investigation (01.08.2020)
Published in The Journal of clinical investigation (01.08.2020)
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Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease
Fujita, Toshiro, Shibata, Shigeru, Nagase, Miki, Yoshida, Shigetaka, Kawarazaki, Wakako, Kurihara, Hidetake, Tanaka, Hirotoshi, Miyoshi, Jun, Takai, Yoshimi
Published in Nature medicine (01.12.2008)
Published in Nature medicine (01.12.2008)
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Mineralocorticoid receptor blockade suppresses dietary salt-induced ACEI/ARB-resistant albuminuria in non-diabetic hypertension: a sub-analysis of evaluate study
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Published in Hypertension research (01.04.2019)
Published in Hypertension research (01.04.2019)
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Rac1 deficiency impairs postnatal development of the renal papilla
Ayuzawa, Nobuhiro, Nishimoto, Mitsuhiro, Kawarazaki, Wakako, Oba, Shigeyoshi, Marumo, Takeshi, Aiba, Atsu, Fujita, Toshiro
Published in Scientific reports (24.11.2022)
Published in Scientific reports (24.11.2022)
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Two Mineralocorticoid Receptor-Mediated Mechanisms of Pendrin Activation in Distal Nephrons
Ayuzawa, Nobuhiro, Nishimoto, Mitsuhiro, Ueda, Kohei, Hirohama, Daigoro, Kawarazaki, Wakako, Shimosawa, Tatsuo, Marumo, Takeshi, Fujita, Toshiro
Published in Journal of the American Society of Nephrology (01.04.2020)
Published in Journal of the American Society of Nephrology (01.04.2020)
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Diabetes Induces Aberrant DNA Methylation in the Proximal Tubules of the Kidney
Marumo, Takeshi, Yagi, Shintaro, Kawarazaki, Wakako, Nishimoto, Mitsuhiro, Ayuzawa, Nobuhiro, Watanabe, Atsushi, Ueda, Kohei, Hirahashi, Junichi, Hishikawa, Keiichi, Sakurai, Hiroyuki, Shiota, Kunio, Fujita, Toshiro
Published in Journal of the American Society of Nephrology (01.10.2015)
Published in Journal of the American Society of Nephrology (01.10.2015)
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Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury
Ayuzawa, Nobuhiro, Nagase, Miki, Ueda, Kohei, Nishimoto, Mitsuhiro, Kawarazaki, Wakako, Marumo, Takeshi, Aiba, Atsu, Sakurai, Takayuki, Shindo, Takayuki, Fujita, Toshiro
Published in Hypertension (Dallas, Tex. 1979) (01.01.2016)
Published in Hypertension (Dallas, Tex. 1979) (01.01.2016)
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Aldosterone Is Essential for Angiotensin II-Induced Upregulation of Pendrin
Hirohama, Daigoro, Ayuzawa, Nobuhiro, Ueda, Kohei, Nishimoto, Mitsuhiro, Kawarazaki, Wakako, Watanabe, Atsushi, Shimosawa, Tatsuo, Marumo, Takeshi, Shibata, Shigeru, Fujita, Toshiro
Published in Journal of the American Society of Nephrology (01.01.2018)
Published in Journal of the American Society of Nephrology (01.01.2018)
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PGI2 Analog Attenuates Salt-Induced Renal Injury through the Inhibition of Inflammation and Rac1-MR Activation
Hirohama, Daigoro, Kawarazaki, Wakako, Nishimoto, Mitsuhiro, Ayuzawa, Nobuhiro, Marumo, Takeshi, Shibata, Shigeru, Fujita, Toshiro
Published in International journal of molecular sciences (22.06.2020)
Published in International journal of molecular sciences (22.06.2020)
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Angiotensin II- and Salt-Induced Kidney Injury through Rac1-Mediated Mineralocorticoid Receptor Activation
KAWARAZAKI, Wakako, NAGASE, Miki, YOSHIDA, Shigetaka, TAKEUCHI, Maki, ISHIZAWA, Kenichi, AYUZAWA, Nobuhiro, UEDA, Kohei, FUJITA, Toshiro
Published in Journal of the American Society of Nephrology (01.06.2012)
Published in Journal of the American Society of Nephrology (01.06.2012)
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Aberrant Rac1-mineralocorticoid receptor pathways in salt-sensitive hypertension
Kawarazaki, Wakako, Fujita, Toshiro
Published in Clinical and experimental pharmacology & physiology (01.12.2013)
Published in Clinical and experimental pharmacology & physiology (01.12.2013)
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Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells
Oba, Shigeyoshi, Ayuzawa, Nobuhiro, Nishimoto, Mitsuhiro, Kawarazaki, Wakako, Ueda, Kohei, Hirohama, Daigoro, Kawakami-Mori, Fumiko, Shimosawa, Tatsuo, Marumo, Takeshi, Fujita, Toshiro
Published in Scientific reports (05.11.2018)
Published in Scientific reports (05.11.2018)
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Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney
Watanabe, Atsushi, Marumo, Takeshi, Kawarazaki, Wakako, Nishimoto, Mitsuhiro, Ayuzawa, Nobuhiro, Ueda, Kohei, Hirohama, Daigoro, Tanaka, Toshiya, Yagi, Shintaro, Ota, Satoshi, Nagae, Genta, Aburatani, Hiroyuki, Kumagai, Hiroo, Fujita, Toshiro
Published in American journal of physiology. Renal physiology (01.04.2018)
Published in American journal of physiology. Renal physiology (01.04.2018)
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Local mineralocorticoid receptor activation and the role of Rac1 in obesity-related diabetic kidney disease
Yoshida, Shigetaka, Ishizawa, Kenichi, Ayuzawa, Nobuhiro, Ueda, Kohei, Takeuchi, Maki, Kawarazaki, Wakako, Fujita, Toshiro, Nagase, Miki
Published in Nephron (01.01.2014)
Published in Nephron (01.01.2014)
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Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension
Kawakami-Mori, Fumiko, Nishimoto, Mitsuhiro, Reheman, Latapati, Kawarazaki, Wakako, Ayuzawa, Nobuhiro, Ueda, Kohei, Hirohama, Daigoro, Kohno, Daisuke, Oba, Shigeyoshi, Shimosawa, Tatsuo, Marumo, Takeshi, Fujita, Toshiro
Published in JCI insight (02.11.2018)
Published in JCI insight (02.11.2018)
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Methylation pattern of urinary DNA as a marker of kidney function decline in diabetes
Marumo, Takeshi, Hoshino, Junichi, Kawarazaki, Wakako, Nishimoto, Mitsuhiro, Ayuzawa, Nobuhiro, Hirohama, Daigoro, Yamanouchi, Masayuki, Ubara, Yoshifumi, Okaneya, Toshikazu, Fujii, Takeshi, Yuki, Kazunari, Atsumi, Yoshihito, Sato, Atsuhisa, Arai, Eri, Kanai, Yae, Shimosawa, Tatsuo, Fujita, Toshiro
Published in BMJ open diabetes research & care (01.09.2020)
Published in BMJ open diabetes research & care (01.09.2020)
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Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading
Yoshida, Shigetaka, Ishizawa, Kenichi, Ayuzawa, Nobuhiro, Ueda, Kohei, Takeuchi, Maki, Kawarazaki, Wakako, Fujita, Toshiro, Nagase, Miki
Published in Clinical and experimental nephrology (01.08.2014)
Published in Clinical and experimental nephrology (01.08.2014)
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