Discovery of AS-1763: A Potent, Selective, Noncovalent, and Orally Available Inhibitor of Bruton’s Tyrosine Kinase
Kawahata, Wataru, Asami, Tokiko, Kiyoi, Takao, Irie, Takayuki, Kashimoto, Shigeki, Furuichi, Hatsuo, Sawa, Masaaki
Published in Journal of medicinal chemistry (14.10.2021)
Published in Journal of medicinal chemistry (14.10.2021)
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Journal Article
Design and Synthesis of Novel Amino-triazine Analogues as Selective Bruton’s Tyrosine Kinase Inhibitors for Treatment of Rheumatoid Arthritis
Kawahata, Wataru, Asami, Tokiko, Kiyoi, Takao, Irie, Takayuki, Taniguchi, Haruka, Asamitsu, Yuko, Inoue, Tomoko, Miyake, Takahiro, Sawa, Masaaki
Published in Journal of medicinal chemistry (11.10.2018)
Published in Journal of medicinal chemistry (11.10.2018)
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Journal Article
TR-FRET binding assay targeting unactivated form of Bruton’s tyrosine kinase
Asami, Tokiko, Kawahata, Wataru, Sawa, Masaaki
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
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Journal Article
‘Turn On/Off’ fluorescence probe for the screening of unactivated Bruton’s tyrosine kinase
Kawahata, Wataru, Asami, Tokiko, Fujii, Ikuo, Sawa, Masaaki
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
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Journal Article
SPIRO DERIVATIVE
KAWAHATA WATARU, IWATA YASUHIRO, NAGAO RINA, SAWA AYAKO, NAGAO HARUNA, NAKAYAMA HIROE, SAWA MASAAKI
Year of Publication 08.02.2024
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Year of Publication 08.02.2024
Patent
PHARMACEUTICAL INCLUDING AMINE DERIVATIVE
KAWAHATA WATARU, TOJO SHINGO, URABE DAISUKE, TOMOMITSU YUKO, WATANABE HITOSHI, MORIYAMA HIDEKI
Year of Publication 02.10.2023
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Year of Publication 02.10.2023
Patent
Abstract 1400: AS-1763: a highly potent, noncovalent and next generation BTK inhibitor for the treatment of patients with B-cell malignancies having C481S mutation in BTK
Kawahata, Wataru, Asami, Tokiko, Kiyoi, Takao, Irie, Takayuki, Kashimoto, Shigeki, Furuichi, Hatsuo, Sawa, Masaaki
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
아민 유도체
KAWAHATA WATARU, TOJO SHINGO, URABE DAISUKE, ASAMITSU YUKO, WATANABE HITOSHI, MORIYAMA HIDEKI
Year of Publication 18.05.2023
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Year of Publication 18.05.2023
Patent
PHARMACEUTICAL COMPOSED OF NOVEL ALKYNE DERIVATIVE
KAWAHATA WATARU, IWATA YASUHIRO, TOJO SHINGO, URABE DAISUKE, SAWA AYAKO, TOMOMITSU YUKO, SAWA MASAAKI, MORIYAMA HIDEKI
Year of Publication 09.02.2023
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Year of Publication 09.02.2023
Patent
AMINE DERIVATIVE
ASAMITSU, Yuko, WATANABE, Hitoshi, KAWAHATA, Wataru, URABE, Daisuke, MORIYAMA, Hideki, TOJO, Shingo
Year of Publication 24.03.2022
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Year of Publication 24.03.2022
Patent
NOVEL ALKYNE DERIVATIVE
SAWA, Ayako, ASAMITSU, Yuko, KAWAHATA, Wataru, URABE, Daisuke, MORIYAMA, Hideki, SAWA, Masaaki, IWATA, Yasuhiro, TOJO, Shingo
Year of Publication 05.08.2021
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Year of Publication 05.08.2021
Patent
CYCLIC UREA DERIVATIVE
SAWA, Ayako, NAGAO, Rina, NAGAO, Haruna, NAKAYAMA, Hiroe, ASAMITSU, Yuko, KAWAHATA, Wataru, MORIYAMA, Hideki, SAWA, Masaaki, IWATA, Yasuhiro
Year of Publication 24.03.2022
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Year of Publication 24.03.2022
Patent
신규 옥소이소퀴놀린 유도체
KAWAHATA WATARU, KIYOI TAKAO, ASAMI TOKIKO, IRIE TAKAYUKI, SAWA MASAAKI, KASHIMOTO SHIGEKI
Year of Publication 06.09.2019
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Year of Publication 06.09.2019
Patent