Design and Synthesis of Fluoro Analogues of Vitamin D
Kawagoe, Fumihiro, Mototani, Sayuri, Kittaka, Atsushi
Published in International journal of molecular sciences (01.08.2021)
Published in International journal of molecular sciences (01.08.2021)
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Journal Article
The First Convergent Synthesis of 23,23-Difluoro-25-hydroxyvitamin D3 and Its 24-Hydroxy Derivatives: Preliminary Assessment of Biological Activities
Mototani, Sayuri, Kawagoe, Fumihiro, Yasuda, Kaori, Mano, Hiroki, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in Molecules (Basel, Switzerland) (22.08.2022)
Published in Molecules (Basel, Switzerland) (22.08.2022)
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Journal Article
Efficient Stereo-Selective Fluorination on Vitamin D3 Side-Chain Using Electrophilic Fluorination
Kawagoe, Fumihiro, Mototani, Sayuri, Kittaka, Atsushi
Published in Biomolecules (Basel, Switzerland) (01.01.2024)
Published in Biomolecules (Basel, Switzerland) (01.01.2024)
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Journal Article
Stereoselective Synthesis of 24-Fluoro-25-Hydroxyvitamin D3 Analogues and Their Stability to hCYP24A1-Dependent Catabolism
Kawagoe, Fumihiro, Mototani, Sayuri, Yasuda, Kaori, Mano, Hiroki, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in International journal of molecular sciences (01.11.2021)
Published in International journal of molecular sciences (01.11.2021)
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Journal Article
Synthesis of New 26,27-Difluoro- and 26,26,27,27-Tetrafluoro-25-hydroxyvitamin D3: Effects of Terminal Fluorine Atoms on Biological Activity and Half-life
Kawagoe, Fumihiro, Mototani, Sayuri, Yasuda, Kaori, Mano, Hiroki, Takeuchi, Akiko, Saitoh, Hiroshi, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in Chemical & pharmaceutical bulletin (01.09.2023)
Published in Chemical & pharmaceutical bulletin (01.09.2023)
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Journal Article
The Synthesis and Biological Evaluation of D-Ring-Modified Vitamin D Analogues
Kawagoe, Fumihiro, Mototani, Sayuri, Kittaka, Atsushi
Published in Biomolecules (Basel, Switzerland) (04.11.2021)
Published in Biomolecules (Basel, Switzerland) (04.11.2021)
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Journal Article
Introduction of fluorine atoms to vitamin D3 side-chain and synthesis of 24,24-difluoro-25-hydroxyvitamin D3
Kawagoe, Fumihiro, Mototani, Sayuri, Yasuda, Kaori, Nagasawa, Kazuo, Uesugi, Motonari, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in The Journal of steroid biochemistry and molecular biology (01.12.2019)
Published in The Journal of steroid biochemistry and molecular biology (01.12.2019)
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Journal Article
Elucidation of metabolic pathways of 25-hydroxyvitamin D3 mediated by CYP24A1 and CYP3A using Cyp24a1 knockout rats generated by CRISPR/Cas9 system
Yasuda, Kaori, Nishikawa, Miyu, Okamoto, Kairi, Horibe, Kyohei, Mano, Hiroki, Yamaguchi, Mana, Okon, Risa, Nakagawa, Kimie, Tsugawa, Naoko, Okano, Toshio, Kawagoe, Fumihiro, Kittaka, Atsushi, Ikushiro, Shinichi, Sakaki, Toshiyuki
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Synthesis and CYP24A1-Dependent Metabolism of 23-Fluorinated Vitamin D3 Analogues
Kawagoe, Fumihiro, Yasuda, Kaori, Mototani, Sayuri, Sugiyama, Toru, Uesugi, Motonari, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in ACS omega (30.06.2019)
Published in ACS omega (30.06.2019)
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Journal Article
An efficient route to benzene and phenol derivatives via ring-closing olefin metathesis
Yoshida, Kazuhiro, Horiuchi, Shingo, Iwadate, Noriyuki, Kawagoe, Fumihiro, Imamoto, Tsuneo
Published in Synlett (18.06.2007)
Published in Synlett (18.06.2007)
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Journal Article
Ring-closing olefin metathesis for the synthesis of benzene derivatives
Yoshida, Kazuhiro, Kawagoe, Fumihiro, Iwadate, Noriyuki, Takahashi, Hidetoshi, Imamoto, Tsuneo
Published in Chemistry, an Asian journal (20.10.2006)
Published in Chemistry, an Asian journal (20.10.2006)
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Journal Article
Synthesis of (22R)‑, (22S)‑22-Fluoro‑, and 22,22-Difluoro-25-hydroxyvitamin D3 and Effects of Side-Chain Fluorination on Biological Activity and CYP24A1-Dependent Metabolism
Kawagoe, Fumihiro, Mototani, Sayuri, Yasuda, Kaori, Takeuchi, Akiko, Mano, Hiroki, Kakuda, Shinji, Saitoh, Hiroshi, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in Journal of organic chemistry (01.09.2023)
Published in Journal of organic chemistry (01.09.2023)
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Journal Article
Synthesis of (22 R )-, (22 S )-22-Fluoro-, and 22,22-Difluoro-25-hydroxyvitamin D 3 and Effects of Side-Chain Fluorination on Biological Activity and CYP24A1-Dependent Metabolism
Kawagoe, Fumihiro, Mototani, Sayuri, Yasuda, Kaori, Takeuchi, Akiko, Mano, Hiroki, Kakuda, Shinji, Saitoh, Hiroshi, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in Journal of organic chemistry (01.09.2023)
Published in Journal of organic chemistry (01.09.2023)
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Journal Article
The First Convergent Synthesis of 23,23-Difluoro-25-hydroxyvitamin D[sub.3] and Its 24-Hydroxy Derivatives: Preliminary Assessment of Biological Activities
Mototani, Sayuri, Kawagoe, Fumihiro, Yasuda, Kaori, Mano, Hiroki, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in Molecules (Basel, Switzerland) (01.08.2022)
Published in Molecules (Basel, Switzerland) (01.08.2022)
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Journal Article
Synthesis of new 26,27-difluoro- and 26,26,27,27-tetrafluoro-25-hydroxyvitamin D3: Effects of terminal fluorine atoms on biological activity and half-life
Kawagoe, Fumihiro, Mototani, Sayuri, Yasuda, Kaori, Mano, Hiroki, Takeuchi, Akiko, Saitoh, Hiroshi, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in Chemical and Pharmaceutical Bulletin (2023)
Published in Chemical and Pharmaceutical Bulletin (2023)
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Journal Article