Positive and Negative Modulation of Group I Metabotropic Glutamate Receptors
Vanejevs, Maksims, Jatzke, Claudia, Renner, Steffen, Müller, Sibylle, Hechenberger, Mirko, Bauer, Tanja, Klochkova, Anna, Pyatkin, Ilya, Kazyulkin, Denis, Aksenova, Elena, Shulepin, Sergey, Timonina, Olga, Haasis, Ariane, Gutcaits, Aleksandrs, Parsons, Christopher G, Kauss, Valerjans, Weil, Tanja
Published in Journal of medicinal chemistry (14.02.2008)
Published in Journal of medicinal chemistry (14.02.2008)
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Journal Article
Pharmacological approaches to tackle NCLs
Kauss, Valerjans, Dambrova, Maija, Medina, Diego Luis
Published in Biochimica et biophysica acta. Molecular basis of disease (01.09.2020)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.09.2020)
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Journal Article
Synthesis of 3,4-dihydro-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxides and their evaluation as ligands for NMDA receptor glycine binding site
Bluke, Zanda, Paass, Einars, Sladek, Meik, Abel, Ulrich, Kauss, Valerjans
Published in Journal of enzyme inhibition and medicinal chemistry (01.08.2016)
Published in Journal of enzyme inhibition and medicinal chemistry (01.08.2016)
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Journal Article
Synthesis of 3,4-dihydro-2 H -1,2-benzothiazine-3-carboxylic acid 1,1-dioxides and their evaluation as ligands for NMDA receptor glycine binding site
Bluke, Zanda, Paass, Einars, Sladek, Meik, Abel, Ulrich, Kauss, Valerjans
Published in Journal of enzyme inhibition and medicinal chemistry (03.07.2016)
Published in Journal of enzyme inhibition and medicinal chemistry (03.07.2016)
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Journal Article
Evaluation of an enantioselective synthesis of 6-chloro-3,4-dihydro-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide and its derivatives
Bluke, Zanda, Sladek, Meik, Abel, Ulrich, Kauss, Valerjans
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01.02.2015)
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01.02.2015)
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Journal Article
Discovery, synthesis, and structure–activity relationships of 2-aminoquinazoline derivatives as a novel class of metabotropic glutamate receptor 5 negative allosteric modulators
Kubas, Holger, Meyer, Udo, Krueger, Bjoern, Hechenberger, Mirko, Vanejevs, Maksims, Zemribo, Ronalds, Kauss, Valerjans, Ambartsumova, Raisa, Pyatkin, Ilya, Polosukhin, Alexey I., Abel, Ulrich
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
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Journal Article
Synergism of virtual screening and medicinal chemistry: Identification and optimization of allosteric antagonists of metabotropic glutamate receptor 1
Noeske, Tobias, Trifanova, Dina, Kauss, Valerjans, Renner, Steffen, Parsons, Christopher G., Schneider, Gisbert, Weil, Tanja
Published in Bioorganic & medicinal chemistry (01.08.2009)
Published in Bioorganic & medicinal chemistry (01.08.2009)
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Journal Article
Diastereoselectivity in the Overman rearrangement of O-cyclohexylideneethylimidates
Jaunzeme, Ieva, Jirgensons, Aigars, Kauss, Valerjans, Liepins, Eduards
Published in Tetrahedron letters (05.06.2006)
Published in Tetrahedron letters (05.06.2006)
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Journal Article
Virtual Screening for Selective Allosteric mGluR1 Antagonists and Structure-Activity Relationship Investigations for Coumarine Derivatives
Noeske, Tobias, Jirgensons, Aigars, Starchenkovs, Igors, Renner, Steffen, Jaunzeme, Ieva, Trifanova, Dina, Hechenberger, Mirko, Bauer, Tanja, Kauss, Valerjans, Parsons, Christopher G., Schneider, Gisbert, Weil, Tanja
Published in ChemMedChem (10.12.2007)
Published in ChemMedChem (10.12.2007)
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Journal Article
PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE
ERDMANE ELINA, KAUSS VALERJANS, GRAVIUS ANDREAS, HENRICH MARKUS, NAGEL JENS, ZEMRIBO RONALDS, WEIL TANJA, MUELLER SIBYLLE
Year of Publication 03.11.2010
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Year of Publication 03.11.2010
Patent
The synthesis of potential Neramexane metabolites: cis- and trans-3-amino-1,3,5,5-tetramethylcyclohexanecarboxylic acids
Trifanova, Dina, Trifonova, Marija, Jirgensons, Aigars, Kauss, Valerjans, Pugovich, Osvalds, Kalvinsh, Ivars, Quack, Guenter
Published in Tetrahedron letters (25.10.2004)
Published in Tetrahedron letters (25.10.2004)
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Journal Article
ETHYNYLXANTHINES, PREPARATION AND USE FOR CANCER TREATMENT
KANEPE-LAPSA, IVETA, DOMRACHEVA, ILONA, VASILJEVA, JELENA, KAUSS, VALERJANS, ARSENJANS, PAVELS, SHESTAKOVA, IRINA, GULBE, ANITA, KALVINS, IVARS
Year of Publication 01.03.2022
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Year of Publication 01.03.2022
Patent
Positive and Negative Modulation of Group I Metabotropic Glutamate Receptors
VANEJEVS, Maksims, JATZKE, Claudia, SHULEPIN, Sergey, TIMONINA, Olga, HAASIS, Ariane, GUTCAITS, Aleksandrs, PARSONS, Christopher G, KAUSS, Valerjans, WEIL, Tanja, RENNER, Steffen, MÜLLER, Sibylle, HECHENBERGER, Mirko, BAUER, Tanja, KLOCHKOVA, Anna, PYATKIN, Ilya, KAZYULKIN, Denis, AKSENOVA, Elena
Published in Journal of medicinal chemistry (2008)
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Published in Journal of medicinal chemistry (2008)
Journal Article
Ethynylxanthines, preparation and use for cancer treatment
Valerjans Kauss, Ilona Domracheva, Irina Shestakova, Anita Gulbe, Jelena Vasiljeva, Pavels Arsenjans, Ivars Kalvins, Iveta Kanepe-Lapsa
Year of Publication 03.06.2020
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Year of Publication 03.06.2020
Patent
Synthesis and structure–affinity relationships of 1,3,5-alkylsubstituted cyclohexylamines binding at NMDA receptor PCP site
Jirgensons, Aigars, Kauss, Valerjans, Kalvinsh, Ivars, Gold, Markus R, Danysz, Wojciech, Parsons, Chris G, Quack, Gunter
Published in European journal of medicinal chemistry (01.06.2000)
Published in European journal of medicinal chemistry (01.06.2000)
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Journal Article
Ethynylxanthines, preparation and use as calcium ion channel modulators
Valerjans Kauss, Ilona Domracheva, Irina Shestakova, Anita Gulbe, Jelena Vasiljeva, Pavels Arsenjans, Ivars Kalvins, Iveta Kanepe-Lapsa
Year of Publication 18.04.2018
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Year of Publication 18.04.2018
Patent
Ethynylxanthines, preparation and use for cancer treatment
Valerjans Kauss, Ilona Domracheva, Irina Shestakova, Anita Gulbe, Jelena Vasiljeva, Pavels Arsenjans, Ivars Kalvins, Iveta Kanepe-Lapsa
Year of Publication 18.04.2018
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Year of Publication 18.04.2018
Patent