A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges
Oshimura, Mitsuo, Uno, Narumi, Kazuki, Yasuhiro, Katoh, Motonobu, Inoue, Toshiaki
Published in Chromosome research (01.02.2015)
Published in Chromosome research (01.02.2015)
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SIRT2 down‐regulation in HeLa can induce p53 accumulation via p38 MAPK activation‐dependent p300 decrease, eventually leading to apoptosis
Li, Yanze, Matsumori, Haruka, Nakayama, Yuji, Osaki, Mitsuhiko, Kojima, Hirotada, Kurimasa, Akihiro, Ito, Hisao, Mori, Seiichi, Katoh, Motonobu, Oshimura, Mitsuo, Inoue, Toshiaki
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.01.2011)
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.01.2011)
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Journal Article
Integration-free iPS cells engineered using human artificial chromosome vectors
Hiratsuka, Masaharu, Uno, Narumi, Ueda, Kana, Kurosaki, Hajime, Imaoka, Natsuko, Kazuki, Kanako, Ueno, Etsuya, Akakura, Yutaro, Katoh, Motonobu, Osaki, Mitsuhiko, Kazuki, Yasuhiro, Nakagawa, Masato, Yamanaka, Shinya, Oshimura, Mitsuo
Published in PloS one (05.10.2011)
Published in PloS one (05.10.2011)
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Journal Article
Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next‐generation human artificial chromosomes for Duchenne muscular dystrophy
Benedetti, Sara, Uno, Narumi, Hoshiya, Hidetoshi, Ragazzi, Martina, Ferrari, Giulia, Kazuki, Yasuhiro, Moyle, Louise Anne, Tonlorenzi, Rossana, Lombardo, Angelo, Chaouch, Soraya, Mouly, Vincent, Moore, Marc, Popplewell, Linda, Kazuki, Kanako, Katoh, Motonobu, Naldini, Luigi, Dickson, George, Messina, Graziella, Oshimura, Mitsuo, Cossu, Giulio, Tedesco, Francesco Saverio
Published in EMBO molecular medicine (01.02.2018)
Published in EMBO molecular medicine (01.02.2018)
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Journal Article
Retargeting of microcell fusion towards recipient cell-oriented transfer of human artificial chromosome
Hiratsuka, Masaharu, Ueda, Kana, Uno, Narumi, Uno, Katsuhiro, Fukuhara, Sayaka, Kurosaki, Hajime, Takehara, Shoko, Osaki, Mitsuhiko, Kazuki, Yasuhiro, Kurosawa, Yoshikazu, Nakamura, Takafumi, Katoh, Motonobu, Oshimura, Mitsuo
Published in BMC biotechnology (19.06.2015)
Published in BMC biotechnology (19.06.2015)
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Journal Article
SIRT2 downregulation confers resistance to microtubule inhibitors by prolonging chronic mitotic arrest
Inoue, Toshiaki, Nakayama, Yuji, Yamada, Hidetoshi, Li, Yanze C., Yamaguchi, Shigeyuki, Osaki, Mitsuhiko, Kurimasa, Akihiro, Hiratsuka, Masaharu, Katoh, Motonobu, Oshimura, Mitsuo
Published in Cell cycle (Georgetown, Tex.) (15.04.2009)
Published in Cell cycle (Georgetown, Tex.) (15.04.2009)
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Journal Article
The transfer of human artificial chromosomes via cryopreserved microcells
Uno, Narumi, Uno, Katsuhiro, Zatti, Susi, Ueda, Kana, Hiratsuka, Masaharu, Katoh, Motonobu, Oshimura, Mitsuo
Published in Cytotechnology (Dordrecht) (01.10.2013)
Published in Cytotechnology (Dordrecht) (01.10.2013)
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Journal Article
Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer
Katoh, Motonobu, Kazuki, Yasuhiro, Kazuki, Kanako, Kajitani, Naoyo, Takiguchi, Masato, Nakayama, Yuji, Nakamura, Takafumi, Oshimura, Mitsuo
Published in BMC biotechnology (06.05.2010)
Published in BMC biotechnology (06.05.2010)
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Journal Article
Construction of a novel human artificial chromosome vector for gene delivery
Katoh, Motonobu, Ayabe, Fumiaki, Norikane, Satoko, Okada, Teruaki, Masumoto, Hiroshi, Horike, Shin-ichi, Shirayoshi, Yasuaki, Oshimura, Mitsuo
Published in Biochemical and biophysical research communications (20.08.2004)
Published in Biochemical and biophysical research communications (20.08.2004)
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Journal Article
A Novel Human Artificial Chromosome Vector Provides Effective Cell Lineage–Specific Transgene Expression in Human Mesenchymal Stem Cells
Ren, Xianying, Katoh, Motonobu, Hoshiya, Hidetoshi, Kurimasa, Akihiro, Inoue, Toshiaki, Ayabe, Fumiaki, Shibata, Kotaro, Toguchida, Junya, Oshimura, Mitsuo
Published in Stem cells (Dayton, Ohio) (01.11.2005)
Published in Stem cells (Dayton, Ohio) (01.11.2005)
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Journal Article
Telomerase-mediated life-span extension of human primary fibroblasts by human artificial chromosome (HAC) vector
Shitara, Shingo, Kakeda, Minoru, Nagata, Keiko, Hiratsuka, Masaharu, Sano, Akiko, Osawa, Kanako, Okazaki, Akiyo, Katoh, Motonobu, Kazuki, Yasuhiro, Oshimura, Mitsuo, Tomizuka, Kazuma
Published in Biochemical and biophysical research communications (09.05.2008)
Published in Biochemical and biophysical research communications (09.05.2008)
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Journal Article
A novel expression system for genomic DNA loci using a human artificial chromosome vector with transformation-associated recombination cloning
Ayabe, Fumiaki, Katoh, Motonobu, Inoue, Toshiaki, Kouprina, Natalay, Larionov, Vladimir, Oshimura, Mitsuo
Published in Journal of human genetics (01.11.2005)
Published in Journal of human genetics (01.11.2005)
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Journal Article
Frequent loss of imprinting of IGF2 and MEST in lung adenocarcinoma
Kohda, Masakazu, Hoshiya, Hidetoshi, Katoh, Motonobu, Tanaka, Isao, Masuda, Ryo, Takemura, Tamiko, Fujiwara, Mutsunori, Oshimura, Mitsuo
Published in Molecular carcinogenesis (01.08.2001)
Published in Molecular carcinogenesis (01.08.2001)
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Journal Article
Antigen-mediated growth control of hybridoma cells via a human artificial chromosome
Kawahara, Masahiro, Inoue, Toshiaki, Ren, Xianying, Sogo, Takahiro, Yamada, Hidetoshi, Katoh, Motonobu, Ueda, Hiroshi, Oshimura, Mitsuo, Nagamune, Teruyuki
Published in Biochimica et biophysica acta (01.02.2007)
Published in Biochimica et biophysica acta (01.02.2007)
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Journal Article
Heat-regulated production and secretion of insulin from a human artificial chromosome vector
Suda, Tetsuji, Katoh, Motonobu, Hiratsuka, Masaharu, Takiguchi, Masato, Kazuki, Yasuhiro, Inoue, Toshiaki, Oshimura, Mitsuo
Published in Biochemical and biophysical research communications (24.02.2006)
Published in Biochemical and biophysical research communications (24.02.2006)
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Journal Article
Construction of a novel expression system on a human artificial chromosome
Otsuki, Akihiro, Tahimic, Candice G.T., Tomimatsu, Nozomi, Katoh, Motonobu, Chen, David J., Kurimasa, Akihiro, Oshimura, Mitsuo
Published in Biochemical and biophysical research communications (15.04.2005)
Published in Biochemical and biophysical research communications (15.04.2005)
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Journal Article
Loss of imprinting of PEG1/MEST in lung cancer cell lines
Nakanishi, Hirofumi, Suda, Tetsuji, Katoh, Motonobu, Watanabe, Akiko, Igishi, Tadashi, Kodani, Masahiro, Matsumoto, Shingo, Nakamoto, Masaki, Shigeoka, Yasushi, Okabe, Tetsuro, Oshimura, Mitsuo, Shimizu, Eiji
Published in Oncology reports (01.12.2004)
Published in Oncology reports (01.12.2004)
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Journal Article
Exogenous gene expression and growth regulation of hematopoietic cells via a novel human artificial chromosome
Yamada, Hidetoshi, Kunisato, Atsushi, Kawahara, Masahiro, Tahimic, Candice G T, Ren, Xianying, Ueda, Hiroshi, Nagamune, Teruyuki, Katoh, Motonobu, Inoue, Toshiaki, Nishikawa, Mitsuo, Oshimura, Mitsuo
Published in Journal of human genetics (01.02.2006)
Published in Journal of human genetics (01.02.2006)
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Journal Article
Human artificial chromosome vectors meet stem cells
Ren, Xianying, Tahimic, Candice Ginn T, Katoh, Motonobu, Kurimasa, Akihiro, Inoue, Toshiaki, Oshimura, Mitsuo
Published in Stem cell reviews (01.03.2006)
Published in Stem cell reviews (01.03.2006)
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Journal Article
SIRT2 knockdown increases basal autophagy and prevents postslippage death by abnormally prolonging the mitotic arrest that is induced by microtubule inhibitors
Inoue, Toshiaki, Nakayama, Yuji, Li, Yanze, Matsumori, Haruka, Takahashi, Haruka, Kojima, Hirotada, Wanibuchi, Hideki, Katoh, Motonobu, Oshimura, Mitsuo
Published in The FEBS journal (01.06.2014)
Published in The FEBS journal (01.06.2014)
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