Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2
Debets, R, Timans, J C, Homey, B, Zurawski, S, Sana, T R, Lo, S, Wagner, J, Edwards, G, Clifford, T, Menon, S, Bazan, J F, Kastelein, R A
Published in The Journal of immunology (1950) (01.08.2001)
Published in The Journal of immunology (1950) (01.08.2001)
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Interleukin 23 is critical in the pathogenesis of spondyloarthropathy and acts on a novel population of interleukin 23R+ entheseal resident cells
Sherlock, Jonathan P, Joyce-Shaikh, Barbara, Turner, Scott, Sathe, Manjiri, Grein, Jeff, Gorman, Daniel M, Bowman, Edward P, McClanahan, Terrill K, Yearley, Jennifer, Buckley, Christopher D, Kastelein, Robert A, Pierce, Robert H, LaFace, Drake, Cua, Daniel J
Published in The Lancet (British edition) (27.02.2013)
Published in The Lancet (British edition) (27.02.2013)
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IL-23 induces spondyloarthropathy by acting on ROR- gamma t super(+) CD3 super(+)CD4 super(-)CD8 super(-) entheseal resident T cells
Sherlock, Jonathan P, Joyce-Shaikh, Barbara, Turner, Scott P, Chao, Cheng-Chi, Sathe, Manjiri, Grein, Jeff, Gorman, Daniel M, Bowman, Edward P, McClanahan, Terrill K, Yearley, Jennifer H, Eberl, Gerard, Buckley, Christopher D, Kastelein, Robert A, Pierce, Robert H, LaFace, Drake M, Cua, Daniel J
Published in Nature medicine (01.07.2012)
Published in Nature medicine (01.07.2012)
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A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon gamma production
Neighbors, M, Xu, X, Barrat, F J, Ruuls, S R, Churakova, T, Debets, R, Bazan, J F, Kastelein, R A, Abrams, J S, O'Garra, A
Published in The Journal of experimental medicine (06.08.2001)
Published in The Journal of experimental medicine (06.08.2001)
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Journal Article
IL-23 induces spondyloarthropathy by acting on ROR-[gamma]t+ CD3+CD4-CD8- entheseal resident T cells
Sherlock, Jonathan P, Joyce-shaikh, Barbara, Turner, Scott P, Chao, Cheng-chi, Sathe, Manjiri, Grein, Jeff, Gorman, Daniel M, Bowman, Edward P, Mcclanahan, Terrill K, Yearley, Jennifer H, Eberl, Gérard, Buckley, Christopher D, Kastelein, Robert A, Pierce, Robert H, Laface, Drake M, Cua, Daniel J
Published in Nature medicine (01.07.2012)
Published in Nature medicine (01.07.2012)
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PGE2
McKenzie, Brent S, Kastelein, Robert A, Cua, Daniel J
Published in Trends in immunology (01.01.2006)
Published in Trends in immunology (01.01.2006)
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IL25 elicits a multipotent progenitor cell population that promotes T^sub H^2 cytokine responses
Saenz, Steven A, Siracusa, Mark C, Perrigoue, Jacqueline G, Spencer, Sean P, Urban Jr, Joseph F, Tocker, Joel E, Budelsky, Alison L, Kleinschek, Melanie A, Kastelein, Robert A, Kambayashi, Taku, Bhandoola, Avinash, Artis, David
Published in Nature (London) (29.04.2010)
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Published in Nature (London) (29.04.2010)
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IL25 elicits a multipotent progenitor cell population that promotes [T.sub.H]2 cytokine responses
Saenz, Steven A, Siracusa, Mark C, Perrigoue, Jacqueline G, Spencer, Sean P, Urban, Jr., Joseph F, Tocker, Joel E, Budelsky, Alison L, Kleinschek, Melanie A, Kastelein, Robert A, Kambayashi, Taku, Bhandoola, Avinash, Artis, David
Published in Nature (London) (29.04.2010)
Published in Nature (London) (29.04.2010)
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IL-25 elicits a multi-potent progenitor cell population that promotes Th2 cytokine responses
Saenz, Steven A., Siracusa, Mark C., Perrigoue, Jacqueline G., Spencer, Sean P., Urban, Joseph F., Tocker, Joel E., Budelsky, Alison L., Kleinschek, Melanie A., Kastelein, Robert A., Kambayashi, Taku, Bhandoola, Avinash, Artis, David
Published in Nature (London) (03.03.2010)
Published in Nature (London) (03.03.2010)
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The essential role of SIGIRR/TIR8 in regulation of Th2 immune response1
Bulek, Katarzyna, Swaidani, Shadi, Qin, Jinzhong, Lu, Yi, Gulen, Muhammet F., Herjan, Tomasz, Min, Booki, Kastelein, Robert A., Aronica, Mark, Kosz-Vnenchak, Magdalena, Li, Xiaoxia
Published in The Journal of immunology (1950) (01.03.2009)
Published in The Journal of immunology (1950) (01.03.2009)
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OB-BP1/Siglec-6. a leptin- and sialic acid-binding protein of the immunoglobulin superfamily
Patel, N, Brinkman-Van der Linden, E C, Altmann, S W, Gish, K, Balasubramanian, S, Timans, J C, Peterson, D, Bell, M P, Bazan, J F, Varki, A, Kastelein, R A
Published in The Journal of biological chemistry (06.08.1999)
Published in The Journal of biological chemistry (06.08.1999)
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Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling
Boniface, Katia, Bak-Jensen, Kristian S., Li, Ying, Blumenschein, Wendy M., McGeachy, Mandy J., McClanahan, Terrill K., McKenzie, Brent S., Kastelein, Robert A., Cua, Daniel J., de Waal Malefyt, René
Published in The Journal of cell biology (23.03.2009)
Published in The Journal of cell biology (23.03.2009)
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Journal Article
Comparison of the effects of interleukin-1 alpha, interleukin-1 beta and interferon-gamma-inducing factor on the production of interferon-gamma by natural killer
Hunter, C A, Timans, J, Pisacane, P, Menon, S, Cai, G, Walker, W, Aste-Amezaga, M, Chizzonite, R, Bazan, J F, Kastelein, R A
Published in European journal of immunology (01.11.1997)
Published in European journal of immunology (01.11.1997)
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Molecular characterization and modular analysis of human MyD88
Hardiman, G, Rock, F L, Balasubramanian, S, Kastelein, R A, Bazan, J F
Published in Oncogene (05.12.1996)
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Published in Oncogene (05.12.1996)
Journal Article
32 IL-27P28 Protects Mice From EAE
Diveu, Caroline, McGeachy, Mandy J., Sathe, Manjiri, Joyce-Shaikh, Barbara, McClanahan, Terrill, Gorman, Daniel M., Cua, Daniel J., Kastelein, Robert A.
Published in Cytokine (Philadelphia, Pa.) (01.07.2007)
Published in Cytokine (Philadelphia, Pa.) (01.07.2007)
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