Inhibition Of LSD1 As a Therapeutic Strategy For The Treatment Of Acute Myeloid Leukemia
Kruger, Ryan G., Mohammad, Helai, Smitheman, Kimberly, Cusan, Monica, Liu, Yan, Pappalardi, Melissa, Federowicz, Kelly, Van Aller, Glenn, Kasparec, Jiri, Tian, Xinrong, Suarez, Dominic, Rouse, Meagan, Schneck, Jessica, Carson, Jeffrey, McDevitt, Patrick, Ho, Thau, McHugh, Charles, Miller, William, Johnson, Neil, Armstrong, Scott A., Tummino, Peter
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Process Development for a Large Scale Stereoselective Synthesis of (Z)-(1-Bromobut-1-ene-1,2-diyl)dibenzene, a Key Intermediate of a Selective Estrogen Receptor Modulator
Cann, Reginald O, Waltermire, Robert E, Chung, Jihchin, Oberholzer, Matthew, Kasparec, Jiri, Ye, Yun K, Wethman, Robert
Published in Organic process research & development (17.09.2010)
Published in Organic process research & development (17.09.2010)
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A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC
Mohammad, Helai P., Smitheman, Kimberly N., Kamat, Chandrashekhar D., Soong, David, Federowicz, Kelly E., Van Aller, Glenn S., Schneck, Jess L., Carson, Jeffrey D., Liu, Yan, Butticello, Michael, Bonnette, William G., Gorman, Shelby A., Degenhardt, Yan, Bai, Yuchen, McCabe, Michael T., Pappalardi, Melissa B., Kasparec, Jiri, Tian, Xinrong, McNulty, Kenneth C., Rouse, Meagan, McDevitt, Patrick, Ho, Thau, Crouthamel, Michelle, Hart, Timothy K., Concha, Nestor O., McHugh, Charles F., Miller, William H., Dhanak, Dashyant, Tummino, Peter J., Carpenter, Christopher L., Johnson, Neil W., Hann, Christine L., Kruger, Ryan G.
Published in Cancer cell (13.07.2015)
Published in Cancer cell (13.07.2015)
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Abstract 5379: A potent EZH2 inhibitor exhibits long residence time and anti-tumor activity
Ott, Heidi, van Aller, Glenn, Ward, Jessica, Le, BaoChau, Rominger, Cynthia, Foley, James, Korenchuk, Susan, McHugh, Charles, Butticello, Michael, Blackledge, Charles, Brackley, James, Burgess, Joelle, Duquenne, Celine, Johnson, Neil, Kasparec, Jiri, LaFrance, Louis, Li, Mei, McNulty, Kenneth, Newlander, Kenneth, Romeril, Stuart, Schmidt, Stanley, Schulz, Mark, Su, Dai-Shi, Suarez, Dominic, Tian, Xinrong, Carpenter, Christopher, Luengo, Juan, Kruger, Ryan, Knight, Steven, McCabe, Michael T.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract 3513: Inhibition of LSD1 for the treatment of cancer
Smitheman, Kimberly, Cusan, Monica, Liu, Yan, Butticello, Michael, Pappalardi, Melissa, Foley, James, Federowicz, Kelly, Van Aller, Glenn, Kasparec, Jiri, Tian, Xinrong, Suarez, Dominic, Schneck, Jess, Carson, Jeff, McDevitt, Patrick, Ho, Thau, McHugh, Charles, Miller, William, Armstrong, Scott, Hann, Christine, Johnson, Neil, Kruger, Ryan G., Mohammad, Helai P., Kamat, Shekhar
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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CYCLOPROPYLAMINES AS LSD1 INHIBITORS
KASPAREC JIRI, TIAN XINRONG, SUAREZ DOMINIC, ROUSE MEAGAN B, MILLER WILLIAM HENRY, JOHNSON NEIL W
Year of Publication 25.03.2014
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Year of Publication 25.03.2014
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An improved and highly convergent synthesis of 4-substituted-pyrido[2,3- d]pyrimidin-7-ones
Yan, Hongxing, Boehm, Jeffrey C., Jin, Qi, Kasparec, Jiri, Li, Huijie, Zhu, Chongjie, Widdowson, Katherine L., Callahan, James F., Wan, Zehong
Published in Tetrahedron letters (12.02.2007)
Published in Tetrahedron letters (12.02.2007)
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A convenient synthesis of trisubstituted pyrido[2,3- d]pyrimidin-7-ones
Kasparec, Jiri, Adams, Jerry L., Sisko, Joseph, Silva, Domingos J.
Published in Tetrahedron letters (09.06.2003)
Published in Tetrahedron letters (09.06.2003)
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ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS
SU DAI SHI, KNIGHT STEVEN DAVID, ROMERIL STUART PAUL, BURGESS JOELLE LORRAINE, JOHNSON NEIL W, LUENGO JUAN I, LAFRANCE III LOUIS V, KASPAREC JIRI, TIAN XINRONG, NEWLANDER KENNETH ALLEN, BLACKLEDGE JR. CHARLES WILLIAM, SCHULZ MARK, MILLER WILLIAM HENRY
Year of Publication 08.01.2016
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Year of Publication 08.01.2016
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PYRAZOLYLAMINOPYRIDINES AS INHIBITORS OF FAK
KASPAREC JIRI, MELLINGER MARK, XIE REN, FAITG THOMAS H, JOHNSON NEIL W, LIN HONG, ADAMS JERRY LEROY, PENG XIN
Year of Publication 12.07.2011
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Year of Publication 12.07.2011
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CYCLOPROPYLAMINES AS LSD1 INHIBITORS
SUAREZ, Dominic, JOHNSON, Neil, W, KASPAREC, Jiri, TIAN, Xinrong, MILLER, William, Henry, ROUSE, Meagan, B
Year of Publication 19.06.2019
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Year of Publication 19.06.2019
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CYCLOPROPYLAMINES AS LSD1 INHIBITORS
MILLER, WILLIAM HENRY, TIAN, XINRONG, JOHNSON, NEIL W, KASPAREC, JIRI, SUAREZ, DOMINIC, ROUSE, MEAGAN B
Year of Publication 21.05.2019
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Year of Publication 21.05.2019
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