Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial
Geletneky, Karsten, Hajda, Jacek, Angelova, Assia L., Leuchs, Barbara, Capper, David, Bartsch, Andreas J., Neumann, Jan-Oliver, Schöning, Tilman, Hüsing, Johannes, Beelte, Birgit, Kiprianova, Irina, Roscher, Mandy, Bhat, Rauf, von Deimling, Andreas, Brück, Wolfgang, Just, Alexandra, Frehtman, Veronika, Löbhard, Stephanie, Terletskaia-Ladwig, Elena, Fry, Jeremy, Jochims, Karin, Daniel, Volker, Krebs, Ottheinz, Dahm, Michael, Huber, Bernard, Unterberg, Andreas, Rommelaere, Jean
Published in Molecular therapy (06.12.2017)
Published in Molecular therapy (06.12.2017)
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Spontaneous Lytic Replication and Epitheliotropism Define an Epstein-Barr Virus Strain Found in Carcinomas
Tsai, Ming-Han, Raykova, Ana, Klinke, Olaf, Bernhardt, Katharina, Gärtner, Kathrin, Leung, Carol S., Geletneky, Karsten, Sertel, Serkan, Münz, Christian, Feederle, Regina, Delecluse, Henri-Jacques
Published in Cell reports (Cambridge) (01.10.2013)
Published in Cell reports (Cambridge) (01.10.2013)
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Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol
Geletneky, Karsten, Huesing, Johannes, Rommelaere, Jean, Schlehofer, Joerg R, Leuchs, Barbara, Dahm, Michael, Krebs, Ottheinz, von Knebel Doeberitz, Magnus, Huber, Bernard, Hajda, Jacek
Published in BMC cancer (21.03.2012)
Published in BMC cancer (21.03.2012)
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Virotherapy in Germany-Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies
Nettelbeck, Dirk M, Leber, Mathias F, Altomonte, Jennifer, Angelova, Assia, Beil, Julia, Berchtold, Susanne, Delic, Maike, Eberle, Jürgen, Ehrhardt, Anja, Engeland, Christine E, Fechner, Henry, Geletneky, Karsten, Goepfert, Katrin, Holm, Per Sonne, Kochanek, Stefan, Kreppel, Florian, Krutzke, Lea, Kühnel, Florian, Lang, Karl Sebastian, Marchini, Antonio, Moehler, Markus, Mühlebach, Michael D, Naumann, Ulrike, Nawroth, Roman, Nüesch, Jürg, Rommelaere, Jean, Lauer, Ulrich M, Ungerechts, Guy
Published in Viruses (21.07.2021)
Published in Viruses (21.07.2021)
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A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol
Hajda, Jacek, Lehmann, Monika, Krebs, Ottheinz, Kieser, Meinhard, Geletneky, Karsten, Jäger, Dirk, Dahm, Michael, Huber, Bernard, Schöning, Tilman, Sedlaczek, Oliver, Stenzinger, Albrecht, Halama, Niels, Daniel, Volker, Leuchs, Barbara, Angelova, Assia, Rommelaere, Jean, Engeland, Christine E, Springfeld, Christoph, Ungerechts, Guy
Published in BMC cancer (29.08.2017)
Published in BMC cancer (29.08.2017)
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Virotherapy Research in Germany: From Engineering to Translation
Ungerechts, Guy, Engeland, Christine E, Buchholz, Christian J, Eberle, Jürgen, Fechner, Henry, Geletneky, Karsten, Holm, Per Sonne, Kreppel, Florian, Kühnel, Florian, Lang, Karl Sebastian, Leber, Mathias F, Marchini, Antonio, Moehler, Markus, Mühlebach, Michael D, Rommelaere, Jean, Springfeld, Christoph, Lauer, Ulrich M, Nettelbeck, Dirk M
Published in Human gene therapy (01.10.2017)
Published in Human gene therapy (01.10.2017)
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Cytosolic Activation of Cathepsins Mediates Parvovirus H-1-Induced Killing of Cisplatin and TRAIL-Resistant Glioma Cells
DI PIAZZA, Matteo, MADER, Carmen, GELETNEKY, Karsten, HERRERO Y CALLE, Marta, WEBER, Ekkehard, SCHLEHOFER, Jörg, DELEU, Laurent, ROMMELAERE, Jean
Published in Journal of Virology (01.04.2007)
Published in Journal of Virology (01.04.2007)
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Antitumor Vaccination of Patients With Glioblastoma Multiforme: A Pilot Study to Assess Feasibility, Safety, and Clinical Benefit
STEINER, Hans Herbert, BONSANTO, Matteo Mario, BAUER, Harald, KIESSLING, Marika, KUNZE, Stefan, SCHIRRMACHER, Volker, HEROLD-MENDE, Christel, BECKHOVE, Philipp, BRYSCH, Michael, GELETNEKY, Karsten, AHMADI, Rezvan, SCHUELE-FREYER, Rebecca, KREMER, Paul, RANAIE, Golamreza, MATEJIC, Dejana
Published in Journal of clinical oncology (01.11.2004)
Published in Journal of clinical oncology (01.11.2004)
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Primary B-Cell Infection with a ΔBALF4 Epstein-Barr Virus Comes to a Halt in the Endosomal Compartment yet Still Elicits a Potent CD4-Positive Cytotoxic T-Cell Response
Neuhierl, Bernhard, Feederle, Regina, Adhikary, Dinesh, Hub, Birgit, Geletneky, Karsten, Mautner, Josef, Delecluse, Henri-Jacques
Published in Journal of Virology (01.05.2009)
Published in Journal of Virology (01.05.2009)
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Therapeutic implications of the enhanced short and long-term cytotoxicity of radiation treatment followed by oncolytic Parvovirus H-1 infection in high-grade glioma cells
Geletneky, Karsten, Hartkopf, Andreas D., Krempien, Robert, Rommelaere, Jean, Schlehofer, Joerg R.
Published in Bioengineered bugs (01.11.2010)
Published in Bioengineered bugs (01.11.2010)
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A randomised, open label phase III trial with nimotuzumab, an anti-epidermal growth factor receptor monoclonal antibody in the treatment of newly diagnosed adult glioblastoma
Westphal, Manfred, Heese, Oliver, Steinbach, Joachim P, Schnell, Oliver, Schackert, Gabriele, Mehdorn, Maximilian, Schulz, Dirk, Simon, Matthias, Schlegel, Uwe, Senft, Christian, Geletneky, Karsten, Braun, Christian, Hartung, Joachim G, Reuter, Dirk, Metz, Monika Warmuth, Bach, Ferdinand, Pietsch, Torsten
Published in European journal of cancer (1990) (01.03.2015)
Published in European journal of cancer (1990) (01.03.2015)
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ATIM-40. HIGH RATE OF OBJECTIVE ANTI-TUMOR RESPONSE IN 9 PATIENTS WITH GLIOBLASTOMA AFTER VIRO-IMMUNOTHERAPY WITH ONCOLYTIC PARVOVIRUS H-1 IN COMBINATION WITH BEVACICUMAB AND PD-1 CHECKPOINT BLOCKADE
Geletneky, Karsten, Bartsch, Andreas, Weiss, Christian, Bernhard, Helga, Marchini, Antonio, Rommelaere, Jean
Published in Neuro-oncology (Charlottesville, Va.) (05.11.2018)
Published in Neuro-oncology (Charlottesville, Va.) (05.11.2018)
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Oncolytic parvoviruses as cancer therapeutics
Rommelaere, Jean, Geletneky, Karsten, Angelova, Assia L, Daeffler, Laurent, Dinsart, Christiane, Kiprianova, Irina, Schlehofer, Joerg R, Raykov, Zahari
Published in Cytokine & growth factor reviews (01.04.2010)
Published in Cytokine & growth factor reviews (01.04.2010)
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A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine
Latzer, Pauline, Zelba, Henning, Battke, Florian, Reinhardt, Annekathrin, Shao, Borong, Bartsch, Oliver, Rabsteyn, Armin, Harter, Johannes, Schulze, Martin, Okech, Thomas, Golf, Alexander, Kyzirakos-Feger, Christina, Kayser, Simone, Pieper, Natalia, Feldhahn, Magdalena, Wünsche, Julian, Seitz, Christian, Hadaschik, Dirk, Garbe, Claus, Hauser, Till-Karsten, la Fougère, Christian, Biskup, Dirk, Brooke, Dawn, Parker, David, Martens, Uwe M., Illerhaus, Gerald, Blumenthal, Deborah T., Merrell, Ryan, Lorenzo, Luisa Sánchez, Hidvégi, Máté, de Robles, Paula, Kebir, Sied, Li, William W., Li, Vincent W., Williams, Matthew, Miller, Alexandra M., Kesari, Santosh, Castro, Michael, Desjardins, Annick, Ashley, David M., Friedman, Henry S., Wen, Patrick Y., Neil, Elisabeth C., Iwamoto, Fabio M., Sipos, Bence, Geletneky, Karsten, Zender, Lars, Glas, Martin, Reardon, David A., Biskup, Saskia
Published in Nature communications (11.08.2024)
Published in Nature communications (11.08.2024)
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Double-faceted mechanism of parvoviral oncosuppression
Geletneky, Karsten, Nüesch, Jürg PF, Angelova, Assia, Kiprianova, Irina, Rommelaere, Jean
Published in Current opinion in virology (01.08.2015)
Published in Current opinion in virology (01.08.2015)
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