Modular synthesis and modification of novel bifunctional dendrons
Tulli, Ludovico G., Miranda, Daniela, Lee, Cameron C., Sullivan, Yang, Grotzfeld, Robert, Hollingworth, Gregory, Kneuer, Rainer, Karpov, Alexei S.
Published in Organic & biomolecular chemistry (13.03.2019)
Published in Organic & biomolecular chemistry (13.03.2019)
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Journal Article
Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor
Karpov, Alexei S, Amiri, Payman, Bellamacina, Cornelia, Bellance, Marie-Helene, Breitenstein, Werner, Daniel, Dylan, Denay, Regis, Fabbro, Doriano, Fernandez, Cesar, Galuba, Inga, Guerro-Lagasse, Stephanie, Gutmann, Sascha, Hinh, Linda, Jahnke, Wolfgang, Klopp, Julia, Lai, Albert, Lindvall, Mika K, Ma, Sylvia, Möbitz, Henrik, Pecchi, Sabina, Rummel, Gabriele, Shoemaker, Kevin, Trappe, Joerg, Voliva, Charles, Cowan-Jacob, Sandra W, Marzinzik, Andreas L
Published in ACS medicinal chemistry letters (09.07.2015)
Published in ACS medicinal chemistry letters (09.07.2015)
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Journal Article
Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody–Drug Conjugates
Karpov, Alexei S, Abrams, Tinya, Clark, Suzanna, Raikar, Ankita, D’Alessio, Joseph A, Dillon, Michael P, Gesner, Thomas G, Jones, Darryl, Lacaud, Marion, Mallet, William, Martyniuk, Piotr, Meredith, Erik, Mohseni, Morvarid, Nieto-Oberhuber, Cristina M, Palacios, Daniel, Perruccio, Francesca, Piizzi, Grazia, Zurini, Mauro, Bialucha, Carl Uli
Published in ACS medicinal chemistry letters (09.08.2018)
Published in ACS medicinal chemistry letters (09.08.2018)
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Journal Article
Benzimidazolyl-pyrazolo[3,4‑b]pyridinones, Selective Inhibitors of MOLT‑4 Leukemia Cell Growth and Sea Urchin Embryo Spiculogenesis: Target Quest
Lichitsky, Boris V, Komogortsev, Andrey N, Dudinov, Arkady A, Krayushkin, Mikhail M, Khodot, Evgenii N, Samet, Alexander V, Silyanova, Eugenia A, Konyushkin, Leonid D, Karpov, Alexei S, Gorses, Delphine, Radimerski, Thomas, Semenova, Marina N, Kiselyov, Alex S, Semenov, Victor V
Published in ACS combinatorial science (09.12.2019)
Published in ACS combinatorial science (09.12.2019)
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Journal Article
Discovery of Potent and Selective Antibody–Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization
Karpov, Alexei S, Nieto-Oberhuber, Cristina M, Abrams, Tinya, Beng-Louka, Edwige, Blanco, Enrique, Chamoin, Sylvie, Chene, Patrick, Dacquignies, Isabelle, Daniel, Dylan, Dillon, Michael P, Doumampouom-Metoul, Lionel, Drosos, Nikolaos, Fedoseev, Pavel, Furegati, Markus, Granda, Brian, Grotzfeld, Robert M, Hess Clark, Suzanna, Joly, Emilie, Jones, Darryl, Lacaud-Baumlin, Marion, Lagasse-Guerro, Stephanie, Lorenzana, Edward G, Mallet, William, Martyniuk, Piotr, Marzinzik, Andreas L, Mesrouze, Yannick, Nocito, Sandro, Oei, Yoko, Perruccio, Francesca, Piizzi, Grazia, Richard, Etienne, Rudewicz, Patrick J, Schindler, Patrick, Velay, Mélanie, Venstrom, Kristine, Wang, Peiyin, Zurini, Mauro, Lafrance, Marc
Published in ACS medicinal chemistry letters (12.12.2019)
Published in ACS medicinal chemistry letters (12.12.2019)
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Journal Article
A novel one-pot three-component synthesis of 3-halofurans and sequential Suzuki coupling
Karpov, AS, Merkul, E, Oeser, T, Muller, TJJ
Published in Chemical communications (Cambridge, England) (28.05.2005)
Published in Chemical communications (Cambridge, England) (28.05.2005)
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Journal Article
A new convenient approach to chiral β-aryl(heteroaryl)alkylamines
Nenajdenko, Valentine G, Karpov, Alexei S, Balenkova, Elizabeth S
Published in Tetrahedron: asymmetry (15.10.2001)
Published in Tetrahedron: asymmetry (15.10.2001)
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Journal Article
Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton’s Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody–Drug Conjugates
Zhang, Alan, Seiss, Katherine, Laborde, Laurent, Palacio-Ramirez, Sebastian, Guthy, Daniel, Lanter, Mylene, Lorber, Julien, Vulpetti, Anna, Arista, Luca, Zoller, Thomas, Radimerski, Thomas, Thoma, Claudio, Hebach, Christina, Tschantz, William R., Karpov, Alexei, Hollingworth, Gregory J., D’Alessio, Joseph A., Ferretti, Stephane, Burger, Matthew T.
Published in Bioconjugate chemistry (21.02.2024)
Published in Bioconjugate chemistry (21.02.2024)
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Journal Article
Modular synthesis and modification of novel bifunctional dendronsElectronic supplementary information (ESI) available: Synthesis, NMR and HRMS spectra of the building block 7 and the dendrons. Synthesis of the antibody conjugate. DSC analysis of the building blocks 2 and 7. UV-Vis spectrum of the DBCO-modified RPA-T4. MS of RPA-T4. See DOI: 10.1039/c8ob02988a
Tulli, Ludovico G, Miranda, Daniela, Lee, Cameron C, Sullivan, Yang, Grotzfeld, Robert, Hollingworth, Gregory, Kneuer, Rainer, Karpov, Alexei S
Year of Publication 13.03.2019
Year of Publication 13.03.2019
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Journal Article
Synthesis of new bulky bis(pyrazolyl)methane carboxylate (heteroscorpionate) ligands and their complexes with iron, manganese and nickel
Jones, Michael W, Baldwin, Jack E, Cowley, Andrew R, Dilworth, Jonathan R, Karpov, Alexei, Smiljanic, Nicolas, Thompson, Amber L, Adlington, Robert M
Published in Dalton transactions : an international journal of inorganic chemistry (14.12.2012)
Published in Dalton transactions : an international journal of inorganic chemistry (14.12.2012)
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Journal Article
One-Pot Three-Component Synthesis of 3-Halofurans and 3-Chloro-4-iodofurans
Karpov, Alexei S., Merkul, Eugen, Oeser, Thomas, Müller, Thomas J. J.
Published in European Journal of Organic Chemistry (01.07.2006)
Published in European Journal of Organic Chemistry (01.07.2006)
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Journal Article
Kurze Meridianin‐Synthesen durch carbonylierende Alkinylierung; eine Vierkomponenten‐Pyrimidin‐Synthese
Karpov, Alexei S., Merkul, Eugen, Rominger, Frank, Müller, Thomas J. J.
Published in Angewandte Chemie (28.10.2005)
Published in Angewandte Chemie (28.10.2005)
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Journal Article
2,6-Bis(5-(2,2-dimethylpropyl)-1H-pyrazol-3-yl)pyridine as a Ligand for Efficient Actinide(III)/Lanthanide(III) Separation
Bremer, Antje, Ruff, Christian M, Girnt, Denise, Müllich, Udo, Rothe, Jörg, Roesky, Peter W, Panak, Petra J, Karpov, Alexei, Müller, Thomas J. J, Denecke, Melissa A, Geist, Andreas
Published in Inorganic chemistry (07.05.2012)
Published in Inorganic chemistry (07.05.2012)
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