Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney
Rossi, Maarit, Morita, Hiroyuki, Sormunen, Raija, Airenne, Sari, Kreivi, Marjut, Wang, Ling, Fukai, Naomi, Olsen, Bjorn R., Tryggvason, Karl, Soininen, Raija
Published in The EMBO journal (15.01.2003)
Published in The EMBO journal (15.01.2003)
Get full text
Journal Article
Mutations in the codon for a conserved arginine-1563 in the COL4A5 collagen gene in Alport syndrome
Zhou, Jing, Gregory, Martin C., Hertz, Jens Michael, Barker, David F., Atkin, Curtis, Spencer, Edwin S., Tryggvason, Karl
Published in Kidney international (01.03.1993)
Published in Kidney international (01.03.1993)
Get full text
Journal Article
Conference Proceeding
Cardiomyopathy Associated with Microcirculation Dysfunction in Laminin α4 Chain-deficient Mice
Wang, Jianming, Hoshijima, Masahiko, Lam, Jason, Zhou, Zhongjun, Jokiel, Anna, Dalton, Nancy D., Hultenby, Kjell, Ruiz-Lozano, Pilar, Ross, John, Tryggvason, Karl, Chien, Kenneth R.
Published in The Journal of biological chemistry (06.01.2006)
Published in The Journal of biological chemistry (06.01.2006)
Get full text
Journal Article
Deficiency of a Transmembrane Prolyl 4-Hydroxylase in the Zebrafish Leads to Basement Membrane Defects and Compromised Kidney Function
Hyvärinen, Jaana, Parikka, Mataleena, Sormunen, Raija, Rämet, Mika, Tryggvason, Karl, Kivirikko, Kari I., Myllyharju, Johanna, Koivunen, Peppi
Published in The Journal of biological chemistry (31.12.2010)
Published in The Journal of biological chemistry (31.12.2010)
Get full text
Journal Article
Knockdown of Tmem234 in zebrafish results in proteinuria
Rodriguez, Patricia Q, Oddsson, Asmundur, Ebarasi, Lwaki, He, Bing, Hultenby, Kjell, Wernerson, Annika, Betsholtz, Christer, Tryggvason, Karl, Patrakka, Jaakko
Published in American journal of physiology. Renal physiology (01.12.2015)
Published in American journal of physiology. Renal physiology (01.12.2015)
Get full text
Journal Article
Plekhh2, a novel podocyte protein downregulated in human focal segmental glomerulosclerosis, is involved in matrix adhesion and actin dynamics
Perisic, Ljubica, Lal, Mark, Hulkko, Jenny, Hultenby, Kjell, Önfelt, Björn, Sun, Ying, Dunér, Fredrik, Patrakka, Jaakko, Betsholtz, Christer, Uhlen, Mathias, Brismar, Hjalmar, Tryggvason, Karl, Wernerson, Annika, Pikkarainen, Timo
Published in Kidney international (01.11.2012)
Published in Kidney international (01.11.2012)
Get full text
Journal Article
Laminin [alpha]4 Deficient Mice Exhibit Decreased Capacity for Adipose Tissue Expansion and Weight Gain
Vaicik, Marcella K, Thyboll Kortesmaa, Jill, Movérare-Skrtic, Sofia, Kortesmaa, Jarkko, Soininen, Raija, Bergström, Göran, Ohlsson, Claes, Chong, Li Yen, Rozell, Björn, Emont, Margo, Cohen, Ronald N, Brey, Eric M, Tryggvason, Karl
Published in PloS one (13.10.2014)
Published in PloS one (13.10.2014)
Get full text
Journal Article
Nephrin Redistribution on Podocytes Is a Potential Mechanism for Proteinuria in Patients with Primary Acquired Nephrotic Syndrome
Doublier, Sophie, Ruotsalainen, Vesa, Salvidio, Gennaro, Lupia, Enrico, Biancone, Luigi, Conaldi, Pier Giulio, Reponen, Paula, Tryggvason, Karl, Camussi, Giovanni
Published in The American journal of pathology (01.05.2001)
Published in The American journal of pathology (01.05.2001)
Get full text
Journal Article
Recombinant laminin-8 (α 4 β 1 γ 1 ) -: Production, purification, and interactions with integrins
Kortesmaa, J, Yurchenco, P, Tryggvason, K
Published in The Journal of biological chemistry (19.05.2000)
Published in The Journal of biological chemistry (19.05.2000)
Get full text
Journal Article
Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury
Gotha, Lara, Lim, Sang Yup, Osherov, Azriel B, Wolff, Rafael, Qiang, Beiping, Erlich, Ilana, Nili, Nafiseh, Pillarisetti, Sivaram, Chang, Ya-Ting, Tran, Phan-Kiet, Tryggvason, Karl, Hedin, Ulf, Tran-Lundmark, Karin, Advani, Suzanne L, Gilbert, Richard E, Strauss, Bradley H
Published in American journal of physiology. Heart and circulatory physiology (01.08.2014)
Published in American journal of physiology. Heart and circulatory physiology (01.08.2014)
Get full text
Journal Article
Novel INF2 mutation p. L77P in a family with glomerulopathy and Charcot-Marie-Tooth neuropathy
Rodriguez, Patricia Q., Lohkamp, Bernhard, Celsi, Gianni, Mache, Christoph Johannes, Auer-Grumbach, Michaela, Wernerson, Annika, Hamajima, Nobuyuki, Tryggvason, Karl, Patrakka, Jaakko
Published in Pediatric nephrology (Berlin, West) (01.02.2013)
Published in Pediatric nephrology (Berlin, West) (01.02.2013)
Get full text
Journal Article
X-linked Alport syndrome : Natural history in 195 families and genotype- phenotype correlations in males
JAIS, J. P, KNEBELMANN, B, PIRSON, Y, VERELLEN, C, WIESLANDER, J, PERSSON, U, TRYGGVASON, K, MARTIN, P, HERTZ, J. M, SCHRÖDER, C, SANAK, M, KREJCOVA, S, GIATRAS, I, CARVALHO, M. F, SAUS, J, ANTIGNAC, C, SMEETS, H, GUBLER, M. C, DE MARCHI, M, RIZZONI, G, RENIERI, A, WEBER, M, GROSS, O, NETZER, K.-O, FLINTER, F
Published in Journal of the American Society of Nephrology (01.04.2000)
Published in Journal of the American Society of Nephrology (01.04.2000)
Get full text
Journal Article
Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin (vol 10, e0122067, 2015)
Perisic, L, Rodriguez, PQ, Hultenby, K, Sun, Y, Lal, M, Betsholtz, C, Uhlen, M, Wernerson, A, Hedin, U, Pikkarainen, T
Published in PLOS ONE (12.05.2015)
Published in PLOS ONE (12.05.2015)
Get full text
Publication
Novel genetic susceptibility loci for diabetic end-stage renal disease identified through robust naive Bayes classification
Sambo, Francesco, Malovini, Alberto, Sandholm, Niina, Stavarachi, Monica, Forsblom, Carol, Mäkinen, Ville-Petteri, Harjutsalo, Valma, Lithovius, Raija, Gordin, Daniel, Parkkonen, Maija, Saraheimo, Markku, Thorn, Lena M., Tolonen, Nina, Wadén, Johan, He, Bing, Österholm, Anne-May, Tuomilehto, Jaako, Lajer, Maria, Salem, Rany M., McKnight, Amy Jayne, Tarnow, Lise, Panduru, Nicolae M., Barbarini, Nicola, Di Camillo, Barbara, Toffolo, Gianna M., Tryggvason, Karl, Bellazzi, Riccardo, Cobelli, Claudio, Groop, Per-Henrik
Published in Diabetologia (01.08.2014)
Published in Diabetologia (01.08.2014)
Get full text
Journal Article
Co-Localization of Nephrin, Podocin, and the Actin Cytoskeleton : Evidence for a Role in Podocyte Foot Process Formation
Saleem, Moin A, Ni, Lan, Witherden, Ian, Tryggvason, Karl, Ruotsalainen, Vesa, Mundel, Peter, Mathieson, Peter W
Published in The American journal of pathology (01.10.2002)
Published in The American journal of pathology (01.10.2002)
Get full text
Journal Article
Congenital nephrotic syndrome (NPHS1): Features resulting from different mutations in Finnish patients
Patrakka, Jaakko, Kestilä, Marjo, Wartiovaara, Jorma, Ruotsalainen, Vesa, Tissari, Päivi, Lenkkeri, Ulla, Männikkö, Minna, Visapää, Ilona, Holmberg, Christer, Rapola, Juhani, Tryggvason, Karl, Jalanko, Hannu
Published in Kidney international (01.09.2000)
Published in Kidney international (01.09.2000)
Get full text
Journal Article
Conference Proceeding
Melanoma cells produce multiple laminin isoforms and strongly migrate on [alpha]5 laminin(s) via several integrin receptors
Oikawa, Yuko, Hansson, Johan, Sasaki, Takako, Rousselle, Patricia, Domogatskaya, Anna, Rodin, Sergey, Tryggvason, Karl, Patarroyo, Manuel
Published in Experimental cell research (01.05.2011)
Published in Experimental cell research (01.05.2011)
Get full text
Journal Article
A meta-analysis of expression signatures in glomerular disease
Tryggvason, Sam H., Guo, Jing, Nukui, Masatoshi, Norlin, Jenny, Haraldsson, Börje, Jörnvall, Hans, Tryggvason, Karl, He, Liqun
Published in Kidney international (01.09.2013)
Published in Kidney international (01.09.2013)
Get full text
Journal Article