Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection
Khan, Khadija, Karim, Farina, Ganga, Yashica, Bernstein, Mallory, Jule, Zesuliwe, Reedoy, Kajal, Cele, Sandile, Lustig, Gila, Amoako, Daniel, Wolter, Nicole, Samsunder, Natasha, Sivro, Aida, San, James Emmanuel, Giandhari, Jennifer, Tegally, Houriiyah, Pillay, Sureshnee, Naidoo, Yeshnee, Mazibuko, Matilda, Miya, Yoliswa, Ngcobo, Nokuthula, Manickchund, Nithendra, Magula, Nombulelo, Karim, Quarraisha Abdool, von Gottberg, Anne, Abdool Karim, Salim S., Hanekom, Willem, Gosnell, Bernadett I., Lessells, Richard J., de Oliveira, Tulio, Moosa, Mahomed-Yunus S., Sigal, Alex
Published in Nature communications (10.08.2022)
Published in Nature communications (10.08.2022)
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Journal Article
SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape
Cele, Sandile, Karim, Farina, Lustig, Gila, San, James Emmanuel, Hermanus, Tandile, Tegally, Houriiyah, Snyman, Jumari, Moyo-Gwete, Thandeka, Wilkinson, Eduan, Bernstein, Mallory, Khan, Khadija, Hwa, Shi-Hsia, Tilles, Sasha W., Singh, Lavanya, Giandhari, Jennifer, Mthabela, Ntombifuthi, Mazibuko, Matilda, Ganga, Yashica, Gosnell, Bernadett I., Karim, Salim S. Abdool, Hanekom, Willem, Van Voorhis, Wesley C., Ndung’u, Thumbi, Lessells, Richard J., Moore, Penny L., Moosa, Mahomed-Yunus S., de Oliveira, Tulio, Sigal, Alex
Published in Cell host & microbe (09.02.2022)
Published in Cell host & microbe (09.02.2022)
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Journal Article
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy
Greaney, Allison J, Starr, Tyler N, Eguia, Rachel T, Loes, Andrea N, Khan, Khadija, Karim, Farina, Cele, Sandile, Bowen, John E, Logue, Jennifer K, Corti, Davide, Veesler, David, Chu, Helen Y, Sigal, Alex, Bloom, Jesse D
Published in PLoS pathogens (01.02.2022)
Published in PLoS pathogens (01.02.2022)
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Journal Article
Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant
Khan, Khadija, Lustig, Gila, Römer, Cornelius, Reedoy, Kajal, Jule, Zesuliwe, Karim, Farina, Ganga, Yashica, Bernstein, Mallory, Baig, Zainab, Jackson, Laurelle, Mahlangu, Boitshoko, Mnguni, Anele, Nzimande, Ayanda, Stock, Nadine, Kekana, Dikeledi, Ntozini, Buhle, van Deventer, Cindy, Marshall, Terry, Manickchund, Nithendra, Gosnell, Bernadett I., Lessells, Richard J., Karim, Quarraisha Abdool, Abdool Karim, Salim S., Moosa, Mahomed-Yunus S., de Oliveira, Tulio, von Gottberg, Anne, Wolter, Nicole, Neher, Richard A., Sigal, Alex
Published in Nature communications (06.12.2023)
Published in Nature communications (06.12.2023)
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Journal Article
HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave
Karim, Farina, Gazy, Inbal, Cele, Sandile, Zungu, Yenzekile, Krause, Robert, Bernstein, Mallory, Khan, Khadija, Ganga, Yashica, Rodel, Hylton, Mthabela, Ntombifuthi, Mazibuko, Matilda, Muema, Daniel, Ramjit, Dirhona, Ndung'u, Thumbi, Hanekom, Willem, Gosnell, Bernadett, Lessells, Richard J, Wong, Emily B, de Oliveira, Tulio, Moosa, Mahomed-Yunus S, Lustig, Gil, Leslie, Alasdair, Kløverpris, Henrik, Sigal, Alex
Published in eLife (05.10.2021)
Published in eLife (05.10.2021)
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Journal Article
HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway
Krause, Robert, Snyman, Jumari, Shi-Hsia, Hwa, Muema, Daniel, Karim, Farina, Ganga, Yashica, Ngoepe, Abigail, Zungu, Yenzekile, Gazy, Inbal, Bernstein, Mallory, Khan, Khadija, Mazibuko, Matilda, Mthabela, Ntombifuthi, Ramjit, Dirhona, Limbo, Oliver, Jardine, Joseph, Sok, Devin, Wilson, Ian A, Hanekom, Willem, Sigal, Alex, Kløverpris, Henrik, Ndung'u, Thumbi, Leslie, Alasdair
Published in eLife (27.10.2022)
Published in eLife (27.10.2022)
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Journal Article
T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy
Lustig, Gila, Cele, Sandile, Karim, Farina, Derache, Anne, Ngoepe, Abigail, Khan, Khadija, Gosnell, Bernadett I, Moosa, Mahomed-Yunus S, Ntshuba, Ntombi, Marais, Suzaan, Jeena, Prakash M, Govender, Katya, Adamson, John, Kløverpris, Henrik, Gupta, Ravindra K, Harrichandparsad, Rohen, Patel, Vinod B, Sigal, Alex
Published in PLoS pathogens (23.09.2021)
Published in PLoS pathogens (23.09.2021)
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Journal Article
A Novel Sample Processing Method for Rapid Detection of Tuberculosis in the Stool of Pediatric Patients Using the Xpert MTB/RIF Assay
Banada, Padmapriya P, Naidoo, Uvistra, Deshpande, Srinidhi, Karim, Farina, Flynn, JoAnne L, O'Malley, Melanie, Jones, Martin, Nanassy, Oliver, Jeena, Prakash, Alland, David
Published in PloS one (23.03.2016)
Published in PloS one (23.03.2016)
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Journal Article
Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition
Nkosi, Thandeka, Chasara, Caroline, Papadopoulos, Andrea O, Nguni, Tiza L, Karim, Farina, Moosa, Mahomed-Yunus S, Gazy, Inbal, Jambo, Kondwani, Hanekom, Willem, Sigal, Alex, Ndhlovu, Zaza M
Published in eLife (26.07.2022)
Published in eLife (26.07.2022)
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Journal Article
Association Between Human Immunodeficiency Virus Viremia and Compromised Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant
Hwa, Shi-Hsia, Snyman, Jumari, Bernstein, Mallory, Ganga, Yashica, Cele, Sandile, Muema, Daniel, Tan, Chee Wah, Khan, Khadija, Karim, Farina, Hanekom, Willem, Bernstein, Leslie, Kaufmann, Stefan H E, Wang, Lin-Fa, Ndung’u, Thumbi, Sigal, Alex
Published in The Journal of infectious diseases (11.01.2023)
Published in The Journal of infectious diseases (11.01.2023)
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Journal Article
Detailed phenotyping reveals diverse and highly skewed neutrophil subsets in both the blood and airways during active tuberculosis infection
Nhamoyebonde, Shepherd, Chambers, Mark, Ndlovu, Lerato, Karim, Farina, Mazibuko, Matilda, Mhlane, Zoey, Madziwa, Lindiwe, Moosa, Yunus, Moodley, Sashen, Hoque, Monjurul, Leslie, Alasdair
Published in Frontiers in immunology (2024)
Published in Frontiers in immunology (2024)
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Journal Article
Author Correction: Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection
Khan, Khadija, Karim, Farina, Ganga, Yashica, Bernstein, Mallory, Jule, Zesuliwe, Reedoy, Kajal, Cele, Sandile, Lustig, Gila, Amoako, Daniel, Wolter, Nicole, Samsunder, Natasha, Sivro, Aida, San, James Emmanuel, Giandhari, Jennifer, Tegally, Houriiyah, Pillay, Sureshnee, Naidoo, Yeshnee, Mazibuko, Matilda, Miya, Yoliswa, Ngcobo, Nokuthula, Manickchund, Nithendra, Magula, Nombulelo, Karim, Quarraisha Abdool, von Gottberg, Anne, Abdool Karim, Salim S., Hanekom, Willem, Gosnell, Bernadett I., Lessells, Richard J., de Oliveira, Tulio, Moosa, Mahomed-Yunus S., Sigal, Alex
Published in Nature communications (13.10.2022)
Published in Nature communications (13.10.2022)
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Journal Article
Failure to decrease HbA1c levels following TB treatment is associated with elevated Th1/Th17 CD4+ responses
Krause, Robert, Warren, Christian M, Simmons, Joshua D, Rebeiro, Peter F, Maruri, Fernanda, Karim, Farina, Sterling, Timothy R, Koethe, John R, Leslie, Al, van der Heijden, Yuri F
Published in Frontiers in immunology (29.05.2023)
Published in Frontiers in immunology (29.05.2023)
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Journal Article
Myeloid cell expression of CD200R is modulated in active TB disease and regulates Mycobacterium tuberculosis infection in a biomimetic model
Ahmed, Mohamed, Tezera, Liku B, Herbert, Nicholas, Chambers, Mark, Reichmann, Michaela T, Nargan, Kievershen, Kloverpris, Henrik, Karim, Farina, Hlatshwayo, Mbali, Madensein, Rajhmun, Habesh, Munir, Hoque, Monjural, Steyn, Adrie J C, Elkington, Paul T, Leslie, Alasdair J
Published in Frontiers in immunology (30.04.2024)
Published in Frontiers in immunology (30.04.2024)
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Journal Article
Elevated IP-10 at the Protein and Gene Level Associates With Pulmonary TB
Fisher, Kimone L, Moodley, Denelle, Rajkumar-Bhugeloo, Kerishka, Baiyegunhi, Omolara O, Karim, Farina, Ndlovu, Hlumani, Ndung'u, Thumbi, Marakalala, Mohlopheni J
Published in Frontiers in cellular and infection microbiology (27.05.2022)
Published in Frontiers in cellular and infection microbiology (27.05.2022)
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Journal Article
Low pre-existing endemic human coronavirus (HCoV-NL63)-specific T cell frequencies are associated with impaired SARS-CoV-2-specific T cell responses in people living with HIV
Ng'uni, Tiza L, Musale, Vernon, Nkosi, Thandeka, Mandolo, Jonathan, Mvula, Memory, Michelo, Clive, Karim, Farina, Moosa, Mohomed Yunus S, Khan, Khadija, Jambo, Kondwani Charles, Hanekom, Willem, Sigal, Alex, Kilembe, William, Ndhlovu, Zaza M
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
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Journal Article
Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization
Cele, Sandile, Jackson, Laurelle, Khoury, David S., Khan, Khadija, Moyo-Gwete, Thandeka, Tegally, Houriiyah, San, James Emmanuel, Cromer, Deborah, Scheepers, Cathrine, Amoako, Daniel, Karim, Farina, Bernstein, Mallory, Lustig, Gila, Archary, Derseree, Smith, Muneerah, Ganga, Yashica, Jule, Zesuliwe, Reedoy, Kajal, Hwa, Shi-Hsia, Giandhari, Jennifer, Blackburn, Jonathan M., Gosnell, Bernadett I., Karim, Salim S. Abdool, Hanekom, Willem, Network for Genomic Surveillance in, COMMIT-KZN Team, von Gottberg, Anne, Bhiman, Jinal, Lessells, Richard J., Moosa, Mahomed-Yunus S., Davenport, Miles P., de Oliveira, Tulio, Moore, Penny L., Sigal, Alex
Published in Nature (London) (23.12.2021)
Published in Nature (London) (23.12.2021)
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Journal Article
MR1-Restricted MAIT Cells From The Human Lung Mucosal Surface Have Distinct Phenotypic, Functional, and Transcriptomic Features That Are Preserved in HIV Infection
Khuzwayo, Sharon, Mthembu, Maphe, Meermeier, Erin W, Prakadan, Sanjay M, Kazer, Samuel W, Bassett, Thierry, Nyamande, Kennedy, Khan, Dilshaad Fakey, Maharaj, Priya, Mitha, Mohammed, Suleman, Moosa, Mhlane, Zoey, Ramjit, Dirhona, Karim, Farina, Shalek, Alex K, Lewinsohn, David M, Ndung'u, Thumbi, Wong, Emily B
Published in Frontiers in immunology (09.04.2021)
Published in Frontiers in immunology (09.04.2021)
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Journal Article
Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection
Magnoumba, Magalli, Singh, Alveera, Ogongo, Paul, Roider, Julia, Asowata, Osaretin, Fehlings, Michael, Karim, Farina, Ndung'u, Thumbi, Anderson, Frank, Leslie, Alasdair, Kløverpris, Henrik
Published in Frontiers in immunology (30.09.2020)
Published in Frontiers in immunology (30.09.2020)
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Journal Article
HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control
Fardoos, Rabiah, Nyquist, Sarah K., Asowata, Osaretin E., Kazer, Samuel W., Singh, Alveera, Ngoepe, Abigail, Giandhari, Jennifer, Mthabela, Ntombifuthi, Ramjit, Dirhona, Singh, Samita, Karim, Farina, Buus, Søren, Anderson, Frank, Porterfield, J. Zachary, Sibiya, Andile L., Bipath, Rishan, Moodley, Kumeshan, Kuhn, Warren, Berger, Bonnie, Nguyen, Son, de Oliveira, Tulio, Ndung’u, Thumbi, Goulder, Philip, Shalek, Alex K., Leslie, Alasdair, Kløverpris, Henrik N.
Published in Frontiers in immunology (18.10.2022)
Published in Frontiers in immunology (18.10.2022)
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