Germline Mutation of Bap1 Accelerates Development of Asbestos-Induced Malignant Mesothelioma
JINFEI XU, KADARIYA, Yuwaraj, HONGZHUANG PENG, KARAR, Jayashree, RAUSCHER, Frank J, TESTA, Joseph R, CHEUNG, Mitchell, JIANMING PEI, TALARCHEK, Jacqueline, SEMENTINO, Eleonora, YINFEI TAN, MENGES, Craig W, CAI, Kathy Q, LITWIN, Samuel
Published in Cancer research (Chicago, Ill.) (15.08.2014)
Published in Cancer research (Chicago, Ill.) (15.08.2014)
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Journal Article
Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting Multiple Independent Domains
Peng, Hongzhuang, Prokop, Jeremy, Karar, Jayashree, Park, Kyewon, Cao, Li, Harbour, J William, Bowcock, Anne M, Malkowicz, S Bruce, Cheung, Mitchell, Testa, Joseph R, Rauscher, 3rd, Frank J
Published in Cancer research (Chicago, Ill.) (01.03.2018)
Published in Cancer research (Chicago, Ill.) (01.03.2018)
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Journal Article
Dual PI3K/mTOR inhibitor NVP-BEZ235 suppresses hypoxia-inducible factor (HIF)-1α expression by blocking protein translation and increases cell death under hypoxia
Karar, Jayashree, Cerniglia, George J., Lindsten, Tullia, Koumenis, Constantinos, Maity, Amit
Published in Cancer biology & therapy (01.09.2012)
Published in Cancer biology & therapy (01.09.2012)
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Journal Article
Long-term stability of clinical-grade lentiviral vectors for cell therapy
Jadlowsky, Julie K., Leskowitz, Rachel, McKenna, Stephen, Karar, Jayashree, Ma, Yujie, Dai, Anlan, Plesa, Gabriela, Chen, Fang, Alexander, Kathleen, Petrella, Jennifer, Gong, Nan, Hwang, Wei-Ting, Farrelly, Olivia, Barber-Rotenberg, Julie, Christensen, Shannon, Gonzalez, Vanessa E., Chew, Anne, Fraietta, Joseph A., June, Carl H.
Published in Molecular therapy. Methods & clinical development (14.03.2024)
Published in Molecular therapy. Methods & clinical development (14.03.2024)
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Structure and specificity of the bacterial cysteine methyltransferase effector NleE suggests a novel substrate in human DNA repair pathway
Yao, Qing, Zhang, Li, Wan, Xiaobo, Chen, Jing, Hu, Liyan, Ding, Xiaojun, Li, Lin, Karar, Jayashree, Peng, Hongzhuang, Chen, She, Huang, Niu, Rauscher, 3rd, Frank J, Shao, Feng
Published in PLoS pathogens (01.11.2014)
Published in PLoS pathogens (01.11.2014)
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Journal Article
Inhibition of autophagy as a strategy to augment radiosensitization by the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235
Cerniglia, George J, Karar, Jayashree, Tyagi, Sonia, Christofidou-Solomidou, Melpo, Rengan, Ramesh, Koumenis, Constantinos, Maity, Amit
Published in Molecular pharmacology (01.12.2012)
Published in Molecular pharmacology (01.12.2012)
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Abstract 217: A novel class of dimeric quinacrine compounds induce DNA damage and increase the anticancer activity of radiation
Karagounis, Ilias V., Karar, Jayashree, Thomas, Christoforos, Koumenis, Constantinos, Winkler, Jeffrey, Amaravadi, Ravi, Maity, Amit
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
PD46-01 BAP1 DE-UBIQUITINASE IS ALLOSTERICALLY REGULATED BY ASXL1/2: SOMATIC BAP1 MUTATION IN RCC AND OTHER TUMORS INACTIVE THIS REGULATION BY TARGETING MULTIPLE INDEPENDENT DOMAINS
Peng, Hongzhuang, Prokop, Jeremy, Karar, Jayashree, Park, Kyewon, Malkowicz, S. Bruce, Cao, Li, Harbour, J. William, Bowcock, Anne, Cheung, Mitchell, Testa, Joesph A, Rauscher, Frank J
Published in The Journal of urology (01.04.2018)
Published in The Journal of urology (01.04.2018)
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Anti-tumorigenic effects of Type 1 interferon are subdued by integrated stress responses
Bhattacharya, S, HuangFu, W-C, Dong, G, Qian, J, Baker, D P, Karar, J, Koumenis, C, Diehl, J A, Fuchs, S Y
Published in Oncogene (05.09.2013)
Published in Oncogene (05.09.2013)
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Abstract LB-323: Control of DNA repair and genome stability by the colon microbiome: The EPEC bacterially encoded NLEE virulence effector protein methylates and inactivates the human ZRANB3 DNA repair helicase
Karar, Jayashree, Peng, Hongzhuang, Zhang, Li, Yao, Qing, Rosenshine, Ilan, Shao, Feng, Rauscher, Frank J.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 2800: Dual PI3K/mTOR inhibitor NVP BEZ-235 suppresses translation of hypoxia-inducible factor (HIF)-1α and increases cell death under hypoxia
Karar, Jayashree, Cerniglia, George J., Koumenis, Constantinos, Maity, Amit
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Abstract 2804: Radiosensitization by the Dual PI3K/mTOR inhibitor NVP-BEZ235
Cerniglia, George J., Karar, Jayashree, Koumenis, Constantinos, Maity, Amit
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
In Vivo Profiling of Hypoxic Gene Expression in Gliomas Using the Hypoxia Marker EF5 and Laser-capture Microdissection
MAROTTA, Diane, KARAR, Jayashree, ALARCON, Rodolfo, MAITY, Amit, KOCH, Cameron, KOUMENIS, Constantinos, JENKINS, W. Timothy, KUMANOVA, Monika, JENKINS, Kevin W, TOBIAS, John W, BALDWIN, Donald, HATZIGEORGIOU, Artemis, ALEXIOU, Panagiotis, EVANS, Sydney M
Published in Cancer research (Chicago, Ill.) (01.02.2011)
Published in Cancer research (Chicago, Ill.) (01.02.2011)
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LIMD2 Is a Small LIM-Only Protein Overexpressed in Metastatic Lesions That Regulates Cell Motility and Tumor Progression by Directly Binding to and Activating the Integrin-Linked Kinase
HONGZHUANG PENG, TALEBZADEH-FARROOJI, Mehdi, HERLYN, Meenhard, CATON, Andrew J, FREDERICKS, William, MALKOWICZ, Bruce, PATERNO, Christopher S, CAROLIN, Alexandra S, SPEICHER, David W, SKORDALAKES, Emmanuel, QIHONG HUANG, DEDHAR, Shoukat, OSBORNE, Michael J, BORDEN, Katherine L. B, RAUSCHER, Frank J, PROKOP, Jeremy W, MCDONALD, Paul C, KARAR, Jayashree, ZHAOYUAN HOU, MEI HE, KEBEBEW, Electron, ORNTOFT, Torben
Published in Cancer research (Chicago, Ill.) (01.03.2014)
Published in Cancer research (Chicago, Ill.) (01.03.2014)
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Inhibition of Autophagy as a Strategy to Augment Radiosensitization by the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235S
Cerniglia, George J., Karar, Jayashree, Tyagi, Sonia, Christofidou-Solomidou, Melpo, Rengan, Ramesh, Koumenis, Constantinos, Maity, Amit
Published in Molecular pharmacology (01.12.2012)
Published in Molecular pharmacology (01.12.2012)
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Journal Article
Structure and Specificity of the Bacterial Cysteine Methyltransferase Effector NleE Suggests a Novel Substrate in Human DNA Repair Pathway: e1004522
Yao, Qing, Zhang, Li, Wan, Xiaobo, Chen, Jing, Hu, Liyan, Ding, Xiaojun, Li, Lin, Karar, Jayashree, Peng, Hongzhuang, Chen, She, Huang, Niu, Rauscher III, Frank J, Shao, Feng
Published in PLoS pathogens (01.11.2014)
Published in PLoS pathogens (01.11.2014)
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Journal Article
Abstract 992: LIMD2 is a small LIM-only protein overexpressed in metastatic lesions which regulates cell motility and tumor progression by directly binding to and activating the integrin-linked-kinase
Peng, Hongzhuang, Farrooji, Mehdi Taleb Zadeh, Osborne, Michael J., Prokop, Jeremy W., McDonald, Paul C., Karar, Jayashree, Hou, Zhaoyuan, He, Mei, Kebebew, Electron, Orntoft, Torben, Herlyn, Meenhard, Caton, Andrew J., Fredericks, William, Malkowicz, Bruce, Paterno, Christopher S., Carolin, Alexandra S., Speicher, David W., Skordalakes, Emmanuel, Huang, Qihong, Dedhar, Shoukat S., Borden, Katherine L. B., Rauscher, Frank J.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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