Metformin as adjunct antituberculosis therapy
Singhal, Amit, Jie, Liu, Kumar, Pavanish, Hong, Gan Suay, Leow, Melvin Khee-Shing, Paleja, Bhairav, Tsenova, Liana, Kurepina, Natalia, Chen, Jinmiao, Zolezzi, Francesca, Kreiswirth, Barry, Poidinger, Michael, Chee, Cynthia, Kaplan, Gilla, Wang, Yee Tang, De Libero, Gennaro
Published in Science translational medicine (19.11.2014)
Published in Science translational medicine (19.11.2014)
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Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis patient bioaerosols
Dinkele, Ryan, Gessner, Sophia, McKerry, Andrea, Leonard, Bryan, Seldon, Ronnett, Koch, Anastasia S, Morrow, Carl, Gqada, Melitta, Kamariza, Mireille, Bertozzi, Carolyn R, Smith, Brian, McLoud, Courtney, Kamholz, Andrew, Bryden, Wayne, Call, Charles, Kaplan, Gilla, Mizrahi, Valerie, Wood, Robin, Warner, Digby F
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Published in PLoS pathogens (01.02.2021)
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The wide utility of rabbits as models of human diseases
Esteves, Pedro J., Abrantes, Joana, Baldauf, Hanna-Mari, BenMohamed, Lbachir, Chen, Yuxing, Christensen, Neil, González-Gallego, Javier, Giacani, Lorenzo, Hu, Jiafen, Kaplan, Gilla, Keppler, Oliver T., Knight, Katherine L., Kong, Xiang-Peng, Lanning, Dennis K., Le Pendu, Jacques, de Matos, Ana Lemos, Liu, Jia, Liu, Shuying, Lopes, Ana M., Lu, Shan, Lukehart, Sheila, Manabe, Yukari C., Neves, Fabiana, McFadden, Grant, Pan, Ruimin, Peng, Xuwen, de Sousa-Pereira, Patricia, Pinheiro, Ana, Rahman, Masmudur, Ruvoën-Clouet, Natalie, Subbian, Selvakumar, Tuñón, Maria Jesús, van der Loo, Wessel, Vaine, Michael, Via, Laura E., Wang, Shixia, Mage, Rose
Published in Experimental & molecular medicine (01.05.2018)
Published in Experimental & molecular medicine (01.05.2018)
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Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens
Qualls, Joseph E, Pesce, John T, Tuomanen, Elaine I, Orme, Ian M, Murray, Peter J, Kanneganti, Thirumala-Devi, Fitzgerald, Katherine A, Kaplan, Gilla, König, Till, Henao-Tamayo, Marcela, Schleicher, Ulrike, Bogdan, Christian, Koo, Mi-Sun, Basaraba, Randall J, Smith, Amber M, Wynn, Thomas A, El Kasmi, Karim C, Thompson, Robert W
Published in Nature immunology (01.12.2008)
Published in Nature immunology (01.12.2008)
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Aggregation state of Mycobacterium tuberculosis impacts host immunity and augments pulmonary disease pathology
Kolloli, Afsal, Kumar, Ranjeet, Singh, Pooja, Narang, Anshika, Kaplan, Gilla, Sigal, Alex, Subbian, Selvakumar
Published in Communications biology (03.11.2021)
Published in Communications biology (03.11.2021)
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Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis
Das, Rituparna, Koo, Mi-Sun, Kim, Bae Hoon, Jacob, Shevin T., Subbian, Selvakumar, Yao, Jie, Leng, Lin, Levy, Rebecca, Murchison, Charles, Burman, William J., Moore, Christopher C., Scheld, W. Michael, David, John R., Kaplan, Gilla, MacMicking, John D., Bucala, Richard
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2013)
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A combination of baseline plasma immune markers can predict therapeutic response in multidrug resistant tuberculosis
Ferrian, Selena, Manca, Claudia, Lubbe, Sugnet, Conradie, Francesca, Ismail, Nazir, Kaplan, Gilla, Gray, Clive M, Fallows, Dorothy
Published in PloS one (02.05.2017)
Published in PloS one (02.05.2017)
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Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model
Kumar, Ranjeet, Kolloli, Afsal, Singh, Pooja, Vinnard, Christopher, Kaplan, Gilla, Subbian, Selvakumar
Published in Frontiers in cellular and infection microbiology (14.01.2020)
Published in Frontiers in cellular and infection microbiology (14.01.2020)
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Lesion-Specific Immune Response in Granulomas of Patients with Pulmonary Tuberculosis: A Pilot Study
Subbian, Selvakumar, Tsenova, Liana, Kim, Mi-Jeong, Wainwright, Helen C, Visser, Annalie, Bandyopadhyay, Nirmalya, Bader, Joel S, Karakousis, Petros C, Murrmann, Gabriele B, Bekker, Linda-Gail, Russell, David G, Kaplan, Gilla
Published in PloS one (02.07.2015)
Published in PloS one (02.07.2015)
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The resuscitation‐promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro
Kana, Bavesh D., Gordhan, Bhavna G., Downing, Katrina J., Sung, Nackmoon, Vostroktunova, Galina, Machowski, Edith E., Tsenova, Liana, Young, Michael, Kaprelyants, Arseny, Kaplan, Gilla, Mizrahi, Valerie
Published in Molecular microbiology (01.02.2008)
Published in Molecular microbiology (01.02.2008)
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Arginine usage in mycobacteria-infected macrophages depends on autocrine-paracrine cytokine signaling
Qualls, Joseph E, Neale, Geoffrey, Smith, Amber M, Koo, Mi-Sun, DeFreitas, Ashley A, Zhang, Huiyuan, Kaplan, Gilla, Watowich, Stephanie S, Murray, Peter J
Published in Science signaling (17.08.2010)
Published in Science signaling (17.08.2010)
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Effect of standard tuberculosis treatment on plasma cytokine levels in patients with active pulmonary tuberculosis
Riou, Catherine, Perez Peixoto, Blas, Roberts, Lindi, Ronacher, Katharina, Walzl, Gerhard, Manca, Claudia, Rustomjee, Roxana, Mthiyane, Thuli, Fallows, Dorothy, Gray, Clive M, Kaplan, Gilla
Published in PloS one (14.05.2012)
Published in PloS one (14.05.2012)
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Host targeted activity of pyrazinamide in Mycobacterium tuberculosis infection
Manca, Claudia, Koo, Mi-Sun, Peixoto, Blas, Fallows, Dorothy, Kaplan, Gilla, Subbian, Selvakumar
Published in PloS one (28.08.2013)
Published in PloS one (28.08.2013)
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Induction of ER stress in macrophages of tuberculosis granulomas
Seimon, Tracie A, Kim, Mi-Jeong, Blumenthal, Antje, Koo, Jovanka, Ehrt, Sabine, Wainwright, Helen, Bekker, Linda-Gail, Kaplan, Gilla, Nathan, Carl, Tabas, Ira, Russell, David G
Published in PloS one (15.09.2010)
Published in PloS one (15.09.2010)
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Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages
Koo, Mi-Sun, Subbian, Selvakumar, Kaplan, Gilla
Published in Cell communication and signaling (26.01.2012)
Published in Cell communication and signaling (26.01.2012)
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Innate immune response to Mycobacterium tuberculosis Beijing and other genotypes
Wang, Chongzhen, Peyron, Pascale, Mestre, Olga, Kaplan, Gilla, van Soolingen, Dick, Gao, Qian, Gicquel, Brigitte, Neyrolles, Olivier
Published in PloS one (25.10.2010)
Published in PloS one (25.10.2010)
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Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs
Subbian, Selvakumar, Tsenova, Liana, O'Brien, Paul, Yang, Guibin, Koo, Mi-Sun, Peixoto, Blas, Fallows, Dorothy, Dartois, Veronique, Muller, George, Kaplan, Gilla
Published in PLoS pathogens (01.09.2011)
Published in PLoS pathogens (01.09.2011)
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Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response
Rodel, Hylton E, Ferreira, Isabella A T M, Ziegler, Carly G K, Ganga, Yashica, Bernstein, Mallory, Hwa, Shi-Hsia, Nargan, Kievershen, Lustig, Gila, Kaplan, Gilla, Noursadeghi, Mahdad, Shalek, Alex K, Steyn, Adrie J C, Sigal, Alex
Published in Frontiers in microbiology (02.12.2021)
Published in Frontiers in microbiology (02.12.2021)
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Adjunctive Phosphodiesterase-4 Inhibitor Therapy Improves Antibiotic Response to Pulmonary Tuberculosis in a Rabbit Model
Subbian, Selvakumar, Tsenova, Liana, Holloway, Jennifer, Peixoto, Blas, O'Brien, Paul, Dartois, Véronique, Khetani, Vikram, Zeldis, Jerome B., Kaplan, Gilla
Published in EBioMedicine (01.02.2016)
Published in EBioMedicine (01.02.2016)
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