Chromatin mobility is increased at sites of DNA double-strand breaks
Krawczyk, P M, Borovski, T, Stap, J, Cijsouw, T, ten Cate, R, Medema, J P, Kanaar, R, Franken, N A P, Aten, J A
Published in Journal of cell science (01.05.2012)
Published in Journal of cell science (01.05.2012)
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Disruption of maternal DNA repair increases sperm-derived chromosomal aberrations
Marchetti, F, Essers, J, Kanaar, R, Wyrobek, A.J
Published in Proceedings of the National Academy of Sciences - PNAS (06.11.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (06.11.2007)
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Journal Article
Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation
Wang, Hongyan, Zhang, Xiangming, Wang, Ping, Yu, Xiaoyan, Essers, Jeroen, Chen, David, Kanaar, Roland, Takeda, Shunichi, Wang, Ya
Published in Nucleic acids research (01.06.2010)
Published in Nucleic acids research (01.06.2010)
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Fibulin-4 deficiency increases TGF-β signalling in aortic smooth muscle cells due to elevated TGF-β2 levels
Ramnath, N. W. M., Hawinkels, L. J. A. C., van Heijningen, P. M., Riet, L. te, Paauwe, M., Vermeij, M., Danser, A. H. J., Kanaar, R., ten Dijke, P., Essers, J.
Published in Scientific reports (26.11.2015)
Published in Scientific reports (26.11.2015)
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DNA damage responses and chemosensitivity of breast cancer tissue slices ex vivo
Van Gent, D, Naipal, K, Verkaik, N, Meijer, T, Hoeijmakers, J, Van Deurzen, C, Kanaar, R, Jager, A
Published in European journal of cancer (1990) (01.07.2016)
Published in European journal of cancer (1990) (01.07.2016)
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Journal Article
Defective Connective Tissue Remodeling in Smad3 Mice Leads to Accelerated Aneurysmal Growth Through Disturbed Downstream TGF-β Signaling
van der Pluijm, I., van Vliet, N., von der Thusen, J.H., Robertus, J.L., Ridwan, Y., van Heijningen, P.M., van Thiel, B.S., Vermeij, M., Hoeks, S.E., Buijs-Offerman, R.M.G.B., Verhagen, H.J.M., Kanaar, R., Bertoli-Avella, A.M., Essers, J.
Published in EBioMedicine (01.10.2016)
Published in EBioMedicine (01.10.2016)
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Journal Article
Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum
Tanori, M, Pasquali, E, Leonardi, S, Giardullo, P, Di Majo, V, Taccioli, G, Essers, J, Kanaar, R, Mullenders, L H, Atkinson, M J, Mancuso, M, Saran, A, Pazzaglia, S
Published in Oncogene (24.11.2011)
Published in Oncogene (24.11.2011)
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Journal Article
ATP-Dependent Chromatin Remodeling by the Cockayne Syndrome B DNA Repair-Transcription-Coupling Factor
Citterio, Elisabetta, Van Den Boom, Vincent, Schnitzler, Gavin, Kanaar, Roland, Bonte, Edgar, Kingston, Robert E., Hoeijmakers, Jan H. J., Vermeulen, Wim
Published in Molecular and Cellular Biology (01.10.2000)
Published in Molecular and Cellular Biology (01.10.2000)
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Journal Article
Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation
Tan, T.L.R., Essers, J., Citterio, E., Swagemakers, S.M.A., de Wit, J., Benson, F.E., Hoeijmakers, J.H.J., Kanaar, R.
Published in Current biology (25.03.1999)
Published in Current biology (25.03.1999)
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Journal Article
The Rad51 Paralog Rad51B Promotes Homologous Recombinational Repair
Takata, Minoru, Sasaki, Masao S., Sonoda, Eiichiro, Fukushima, Toru, Morrison, Ciaran, Albala, Joanna S., Swagemakers, Sigrid M. A., Kanaar, Roland, Thompson, Larry H., Takeda, Shunichi
Published in Molecular and Cellular Biology (01.09.2000)
Published in Molecular and Cellular Biology (01.09.2000)
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Journal Article
Rad54 is required for the normal development of male and female germ cells and contributes to the maintainance of their genome integrity after genotoxic stress
Messiaen, S, Le Bras, A, Duquenne, C, Barroca, V, Moison, D, Déchamps, N, Doussau, M, Bauchet, A-L, Guerquin, M-J, Livera, G, Essers, J, Kanaar, R, Habert, R, Bernardino-Sgherri, J
Published in Cell death & disease (01.08.2013)
Published in Cell death & disease (01.08.2013)
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PO-442 Ex vivo prostate cancer culture system recapitulates in vivo response to androgen antagonist
Zhang, W, Weerden, W Van, Erkens-Schulze, S, Kanaar, R, Gent, D Van, Nonnekens, J
Published in ESMO open (01.07.2018)
Published in ESMO open (01.07.2018)
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Journal Article
Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques
Holthausen, J T, van Loenhout, M T J, Sanchez, H, Ristic, D, van Rossum-Fikkert, S E, Modesti, M, Dekker, C, Kanaar, R, Wyman, C
Published in Nucleic acids research (01.08.2011)
Published in Nucleic acids research (01.08.2011)
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Journal Article
PO-462 Functional ex vivo assay reveals homologous recombination deficiency in breast cancer beyond brca gene defects
Meijer, T, Verkaik, N, Sieuwerts, A, Deurzen, C Van, Dubbink, HJ, Kanaar, R, Martens, J, Jager, A, Gent, D Van
Published in ESMO open (01.07.2018)
Published in ESMO open (01.07.2018)
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Journal Article
PO-492 Ex vivo functional homologous recombination (HR) test detects BRCA reversal and resistance to PARPi in metastatic breast cancer patients
Meijer, T, Verkaik, N, Deurzen, C Van, Dubbink, HJ, Toom, D Den, Dinjens, W, Kanaar, R, Gent, D Van, Jager, A
Published in ESMO open (01.07.2018)
Published in ESMO open (01.07.2018)
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