Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGFβ signaling
Kong, Ya, Zhang, Yutian, Wang, Hanlin, Kan, Weijuan, Guo, Haoran, Liu, Yun, Zang, Yi, Li, Jia
Published in Oncogene (28.01.2022)
Published in Oncogene (28.01.2022)
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Journal Article
Structure–Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors
Li, Chunpu, Su, Mingbo, Zhu, Wei, Kan, Weijuan, Ge, Tianpeng, Xu, Gaoya, Wang, Shuni, Sheng, Li, Gao, Feng, Ye, Yunfei, Wang, Jiang, Zhou, Yubo, Li, Jia, Liu, Hong
Published in Journal of medicinal chemistry (10.03.2022)
Published in Journal of medicinal chemistry (10.03.2022)
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Journal Article
Targeting C/EBPα overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia
Wang, Hanlin, Luo, Guanghao, Hu, Xiaobei, Xu, Gaoya, Wang, Tao, Liu, Minmin, Qiu, Xiaohui, Li, Jianan, Fu, Jingfeng, Feng, Bo, Tu, Yutong, Kan, Weijuan, Wang, Chang, Xu, Ran, Zhou, Yubo, Yang, Jianmin, Li, Jia
Published in Nature communications (05.04.2023)
Published in Nature communications (05.04.2023)
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Journal Article
Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasis
Dong, Ying, Hu, Hao, Zhang, Xuan, Zhang, Yunkai, Sun, Xin, Wang, Hanlin, Kan, Weijuan, Tan, Min-Jia, Shi, Hong, Zang, Yi, Li, Jia
Published in Signal transduction and targeted therapy (06.03.2023)
Published in Signal transduction and targeted therapy (06.03.2023)
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Targeted Near-Infrared Fluorescence Imaging of Liver Cancer using Dual-Peptide-Functionalized Albumin Particles
Dou, Wei-Tao, Guo, Chen, Zhu, Ling, Qiu, Peng, Kan, Weijuan, Pan, Yu-Fei, Zang, Yi, Dong, Li-Wei, Li, Jia, Tan, Ye-Xiong, Wang, Hong-Yang, He, Xiao-Peng
Published in Chemical & biomedical imaging (22.01.2024)
Published in Chemical & biomedical imaging (22.01.2024)
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Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton’s Tyrosine Kinase for the Treatment of Lymphoma
Zhang, Jingyu, Che, Jinxin, Luo, Xiaomin, Wu, Mingfei, Kan, Weijuan, Jin, Yuheng, Wang, Hanlin, Pang, Ao, Li, Cong, Huang, Wenhai, Zeng, Shenxin, Zhuang, Weihao, Wu, Yizhe, Xu, Yongjin, Zhou, Yubo, Li, Jia, Dong, Xiaowu
Published in Journal of medicinal chemistry (14.07.2022)
Published in Journal of medicinal chemistry (14.07.2022)
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Journal Article
Exploratory research on the effective chemical basis of Tanreqing injection for treating acute lung injury: in vivo, in vitro and in silico
Tang, Bixi, Xie, Like, Wang, Yangyang, Shi, Yulong, Kan, Weijuan, Feng, Bo, Lin, Chenxuan, Xu, Zhijian, Zhu, Weiliang, Li, Jia, Zhang, Xuemei, Tian, Xiaoting, Zang, Yi
Published in Journal of ethnopharmacology (09.09.2024)
Published in Journal of ethnopharmacology (09.09.2024)
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Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors
Luo, Menglan, Ye, Yunfei, Tang, Lu, Kan, Weijuan, Chen, Lin, Li, Cong, Sheng, Li, Zhou, Yubo, Li, Jia, Xiong, Bing, Wang, Hanlin, Chen, Danqi
Published in European journal of medicinal chemistry (15.12.2024)
Published in European journal of medicinal chemistry (15.12.2024)
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Journal Article
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer
Wei, Dan, Wang, Hanlin, Zeng, Qinghe, Wang, Wenjing, Hao, Bingbing, Feng, Xule, Wang, Peipei, Song, Ning, Kan, Weijuan, Huang, Guifang, Zhou, Xiaoyu, Tan, Minjia, Zhou, Yubo, Huang, Ruimin, Li, Jia, Chen, Xiao-Hua
Published in Journal of medicinal chemistry (14.10.2021)
Published in Journal of medicinal chemistry (14.10.2021)
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Journal Article
Design, synthesis and biological evaluation of thioether-containing lenalidomide and pomalidomide derivatives with anti-multiple myeloma activity
Wang, Yuhong, Mi, Tian, Li, Yiming, Kan, Weijuan, Xu, Gaoya, Li, Jingya, Zhou, Yubo, Li, Jia, Jiang, Xuefeng
Published in European journal of medicinal chemistry (01.01.2021)
Published in European journal of medicinal chemistry (01.01.2021)
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Journal Article
Discovery of Novel N‑(5-(Pyridin-3-yl)‑1H‑indazol-3-yl)benzamide Derivatives as Potent Cyclin-Dependent Kinase 7 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease
Yang, Bowen, Zhang, Haoran, Li, Na, Gao, Lixin, Jiang, Hong, Kan, Weijuan, Yuan, Haoxing, Li, Jia, Zhao, Dongmei, Xiong, Bing, Zhou, Yubo, Guo, Dong, Liu, Tongchao
Published in Journal of medicinal chemistry (08.12.2022)
Published in Journal of medicinal chemistry (08.12.2022)
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Journal Article
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5‑((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile
Jin, Tingting, Xu, Lei, Wang, Peipei, Hu, Xiaobei, Zhang, Runyuan, Wu, Zhiqi, Du, Wenxin, Kan, Weijuan, Li, Kun, Wang, Chang, Zhou, Yubo, Li, Jia, Liu, Tao
Published in Journal of medicinal chemistry (28.10.2021)
Published in Journal of medicinal chemistry (28.10.2021)
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Journal Article
Discovery of Novel N -(5-(Pyridin-3-yl)-1 H -indazol-3-yl)benzamide Derivatives as Potent Cyclin-Dependent Kinase 7 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease
Yang, Bowen, Zhang, Haoran, Li, Na, Gao, Lixin, Jiang, Hong, Kan, Weijuan, Yuan, Haoxing, Li, Jia, Zhao, Dongmei, Xiong, Bing, Zhou, Yubo, Guo, Dong, Liu, Tongchao
Published in Journal of medicinal chemistry (08.12.2022)
Published in Journal of medicinal chemistry (08.12.2022)
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Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies
Saidahmatov, Abdusaid, Li, Jianan, Xu, Shihao, Hu, Xiaobei, Gao, Xiangqian, Kan, Weijuan, Gao, Lixin, Li, Cong, Shi, Yuqiang, Sheng, Li, Wang, Peipei, Zhou, Yubo, Liang, Xuewu, Li, Jia, Liu, Hong
Published in Journal of medicinal chemistry (12.09.2024)
Published in Journal of medicinal chemistry (12.09.2024)
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Discovery of a Highly Potent, Selective and Efficacious USP7 Degrader for the Treatment of Acute Lymphoblastic Leukemia
Xu, Miaomiao, Fu, Jingfeng, Pei, Yuan, Li, Mengna, Kan, Weijuan, Yan, Ruyu, Xia, Chaoyue, Ma, Jingkun, Wang, Peipei, Zhang, Yan, Gao, Yue, Yang, Yaxi, Zhou, Yubo, Li, Jia, Zhou, Bing
Published in Journal of medicinal chemistry (08.08.2024)
Published in Journal of medicinal chemistry (08.08.2024)
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Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia
Han, Xu, Song, Ning, Saidahmatov, Abdusaid, Wang, Peipei, Wang, Yong, Hu, Xiaobei, Kan, Weijuan, Zhu, Wei, Gao, Lixin, Zeng, Mingjie, Wang, Yujie, Li, Chunpu, Li, Jia, Liu, Hong, Zhou, Yubo, Wang, Jiang
Published in Journal of medicinal chemistry (14.10.2021)
Published in Journal of medicinal chemistry (14.10.2021)
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브루톤 티로신 키나아제, 이의 돌연변이체 분해제, 조성물 및 응용
ZHOU YUBO, LI JIA, LIU XINGGUO, SU MINGBO, HU MIAO, KAN WEIJUAN, LUO XIAOMIN, XIE JIANGFENG, WU YIZHE, ZHOU XINGLU
Year of Publication 05.03.2024
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Year of Publication 05.03.2024
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Ardisiphenol D, a resorcinol derivative identified from Ardisia brevicaulis, exerts antitumor effect through inducing apoptosis in human non-small-cell lung cancer A549 cells
Zhao, Feng, Hu, Yuan, Chong, Chuanke, Lu, Minghui, Chen, Liping, Kan, Weijuan, Chen, Lei, Liu, Hongwei
Published in Pharmaceutical biology (01.07.2014)
Published in Pharmaceutical biology (01.07.2014)
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이소인돌린계 화합물, 이의 제조 방법, 약학 조성물 및 용도
ZHOU YUBO, XU GAOYA, HU XIAOBEI, KAN WEIJUAN, WANG YUJIE, TIAN HONGTAO, YAN KENIAN, CHENG YU, ZHONG YUHUA, LI JIA, MI TIAN, CHEN XIAOHUA, NIE HUIJUN, ZHOU BINSHAN, FENG LEI
Year of Publication 10.06.2021
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Year of Publication 10.06.2021
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ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND
CHEN, XIAOHUA, WANG, YUJIE, LI, JIA, NIE, HUIJUN, KAN, WEIJUAN, ZHOU, YUBO, CHENG, YU, GUO, ANDI
Year of Publication 03.10.2023
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Year of Publication 03.10.2023
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