Design, Synthesis, and Pharmacological Evaluation of Piperidin-4-yl amino aryl sulfonamides: Novel, Potent, Selective, Orally Active, and Brain Penetrant 5‑HT6 Receptor Antagonists
Nirogi, Ramakrishna, Shinde, Anil, Daulatabad, Anand, Kambhampati, Ramasastri, Gudla, Parandhama, Shaik, Mohammad, Gampa, Muralimohan, Balasubramaniam, Suresh, Gangadasari, Pamuletinarasimhareddy, Reballi, Veena, Badange, Rajeshkumar, Bojja, Kumar, Subramanian, Ramkumar, Bhyrapuneni, Gopinadh, Muddana, Nageswararao, Jayarajan, Pradeep
Published in Journal of medicinal chemistry (08.11.2012)
Published in Journal of medicinal chemistry (08.11.2012)
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Journal Article
Design, synthesis and pharmacological evaluation of 4-(piperazin-1-yl methyl)-N-1-arylsulfonyl indole derivatives as 5-HT6 receptor ligands
Nirogi, Ramakrishna V. S., Badange, Rajeshkumar, Kambhampati, Ramasastri, Chindhe, Anil, Deshpande, Amol D., Tiriveedhi, Vinaykumar, Kandikere, Vishwottam, Muddana, Nageswararao, Abraham, Renny, Khagga, Mukkanti
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
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Journal Article
1-[2- ]-5--3-[4--1- ]-1H- ACTIVE METABOLITE OF 1-[2-BROMOPHENYL SULFONYL]-5-METHOXY-3-[4-METHYL-1-PIPERAZINYL METHYL]-1H-INDOLE DIMESYLATE MONOHYDRATE AND DIMESYLATE DIHYDRATE SALT OF ACTIVE METABOLITE
NIROGI RAMAKRISHNA, SHINDE ANIL KARBHARI, JASTI VENKATESWARLU, KAMBHAMPATI RAMASASTRI
Year of Publication 20.03.2017
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Year of Publication 20.03.2017
Patent
순수한 5-HT6 수용체 길항제, 아세틸콜린에스테라제 저해제 및 NMDA 수용체 길항제의 3중 조합물
NIROGI RAMAKRISHNA, SHINDE ANIL KARBHARI, JAYARAJAN PRADEEP, BHYRAPUNENI GOPINADH, JASTI VENKATESWARLU, KAMBHAMPATI RAMASASTRI
Year of Publication 08.01.2019
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Year of Publication 08.01.2019
Patent
순수한 5-HT6 수용체 길항제와 아세틸콜린에스테라제 저해제의 조합물
NIROGI RAMAKRISHNA, SHINDE ANIL KARBHARI, JAYARAJAN PRADEEP, BHYRAPUNENI GOPINADH, JASTI VENKATESWARLU, KAMBHAMPATI RAMASASTRI
Year of Publication 08.01.2019
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Year of Publication 08.01.2019
Patent
순수한 5-HT6 수용체 길항제 및 NMDA 수용체 길항제의 조합물
NIROGI RAMAKRISHNA, SHINDE ANIL KARBHARI, JAYARAJAN PRADEEP, BHYRAPUNENI GOPINADH, JASTI VENKATESWARLU, KAMBHAMPATI RAMASASTRI
Year of Publication 24.12.2018
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Year of Publication 24.12.2018
Patent
Design, synthesis and pharmacological evaluation of 4-(piperazin-1-yl methyl)-N1-arylsulfonyl indole derivatives as 5-HT6 receptor ligands
Nirogi, Ramakrishna V.S., Badange, Rajeshkumar, Kambhampati, Ramasastri, Chindhe, Anil, Deshpande, Amol D., Tiriveedhi, Vinaykumar, Kandikere, Vishwottam, Muddana, Nageswararao, Abraham, Renny, Khagga, Mukkanti
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
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Journal Article
Indole-3-piperazinyl derivatives: Novel chemical class of 5-HT6 receptor antagonists
Nirogi, Ramakrishna V.S., Deshpande, Amol D., Kambhampati, Ramasastri, Badange, Rajesh Kumar, Kota, Laxman, Daulatabad, Anand V., Shinde, Anil K., Ahmad, Ishtiyaque, Kandikere, Vishwottam, Jayarajan, Pradeep, Dubey, P.K.
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Journal Article
Design, Synthesis, and Pharmacological Evaluation of Piperidin-4-yl amino aryl sulfonamides: Novel, Potent, Selective, Orally Active, and Brain Penetrant 5-HT 6 Receptor Antagonists
Nirogi, Ramakrishna, Shinde, Anil, Daulatabad, Anand, Kambhampati, Ramasastri, Gudla, Parandhama, Shaik, Mohammad, Gampa, Muralimohan, Balasubramaniam, Suresh, Gangadasari, Pamuletinarasimhareddy, Reballi, Veena, Badange, Rajeshkumar, Bojja, Kumar, Subramanian, Ramkumar, Bhyrapuneni, Gopinadh, Muddana, Nageswararao, Jayarajan, Pradeep
Published in Journal of medicinal chemistry (08.11.2012)
Published in Journal of medicinal chemistry (08.11.2012)
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Journal Article
P3‐390: EFFECT OF GENDER AND FOOD ON THE SINGLE‐DOSE PHARMACOKINETICS OF SUVN‐502, A POTENT AND SELECTIVE 5‐HT6 RECEPTOR ANTAGONIST
Nirogi, Ramakrishna, Mudigonda, Koteshwara, Penta, Kiran Kumar, Bhyrapuneni, Gopinadh, Ajjala, Devender Reddy, Muddana, Nageswararao, Benade, Vijay S., Palacharla, Raghava Chowdary, Goyal, Vinod Kumar, Pandey, Santosh Kumar, Abraham, Renny, Jayarajan, Pradeep, Badange, Rajesh Kumar, Kambhampati, Ramasastri
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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Journal Article
EFFECT OF GENDER AND FOOD ON THE SINGLE-DOSE PHARMACOKINETICS OF SUVN-502, A POTENT AND SELECTIVE 5-HT6 RECEPTOR ANTAGONIST
Nirogi, Ramakrishna, Mudigonda, Koteshwara, Penta, Kiran Kumar, Bhyrapuneni, Gopinadh, Ajjala, Devender Reddy, Muddana, Nageswararao, Benade, Vijay S, Palacharla, Raghava Chowdary, Goyal, Vinod Kumar, Pandey, Santosh Kumar, Abraham, Renny, Jayarajan, Pradeep, Badange, Rajesh Kumar, Kambhampati, Ramasastri
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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Journal Article
P1‐263: Pro‐cognitive properties SUVN‐D1108121, a potent and selective 5‐HT4 receptor partial agonist
Nirogi, Ramakrishna, Abraham, Renny, Benade, Vijay, Bhyrapuneni, Gopinadh, Das, Abinash, Manoharan, Arunkumar, Yaramasu, Ramu, Shinde, Anil, Kambhampati, Ramasastri, Dwarampudi, Adireddy
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Journal Article
Pro-cognitive properties SUVN-D1108121, a potent and selective 5-HT4 receptor partial agonist
Nirogi, Ramakrishna, Abraham, Renny, Benade, Vijay, Bhyrapuneni, Gopinadh, Das, Abinash, Manoharan, Arunkumar, Yaramasu, Ramu, Shinde, Anil, Kambhampati, Ramasastri, Dwarampudi, Adireddy
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Journal Article
Synthesis and structure-activity relationship of novel conformationally restricted analogues of serotonin as 5-HT6 receptor ligands
Nirogi, Ramakrishna V.S., Kambhampati, Ramasastri, Kothmirkar, Prabhakar, Konda, Jagadishbabu, Bandyala, Thrinath Reddy, Gudla, Parandhama, Arepalli, Sobhanadri, Gangadasari, Narasimhareddy P., Shinde, Anil K., Deshpande, Amol D., Dwarampudi, Adireddy, Chindhe, Anil K., Dubey, Pramod Kumar
Published in Journal of enzyme inhibition and medicinal chemistry (01.06.2012)
Published in Journal of enzyme inhibition and medicinal chemistry (01.06.2012)
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Journal Article
P3‐451: SUVN‐502: A potent and selective 5‐HT6 antagonist, potential drug for the treatment of Alzheimer's disease
Nirogi, Ramakrishna, Kandikere, Vishwottam, Mudigonda, Koteshwara, Bhyrapuneni, Gopinadh, Shinde, Anil, Kambhampati, Ramasastri, Jayarajan, Pradeep, Abraham, Renny, Mulla, Mohamad Sadik, Muddana, Nageswararao, Benade, Vijay, Saralaya, Ramanatha
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
SUVN-502: A potent and selective 5-HT6 antagonist, potential drug for the treatment of Alzheimer's disease
Nirogi, Ramakrishna, Kandikere, Vishwottam, Mudigonda, Koteshwara, Bhyrapuneni, Gopinadh, Shinde, Anil, Kambhampati, Ramasastri, Jayarajan, Pradeep, Abraham, Renny, Mulla, Mohamad Sadik, Muddana, Nageswararao, Benade, Vijay, Saralaya, Ramanatha
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
Design, synthesis and pharmacological evaluation of conformationally restricted N-arylsulfonyl-3-aminoalkoxy indoles as a potential 5-HT6 receptor ligands
Nirogia, Ramakrishna V.S., Kambhampati, Ramasastri, Daulatabad, Anand V., Gudla, Parandhama, Shaikh, Mohammad, Achanta, Pramod Kumar, Shinde, Anil K., Dubey, Pramod Kumar
Published in Journal of enzyme inhibition and medicinal chemistry (01.06.2011)
Published in Journal of enzyme inhibition and medicinal chemistry (01.06.2011)
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Journal Article
Indole-3-piperazinyl derivatives: Novel chemical class of 5-HT sub(6) receptor antagonists
Nirogi, Ramakrishna VS, Deshpande, Amol D, Kambhampati, Ramasastri, Badange, Rajesh Kumar, Kota, Laxman, Daulatabad, Anand V, Shinde, Anil K, Ahmad, Ishtiyaque, Kandikere, Vishwottam, Jayarajan, Pradeep, Dubey, P K
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Journal Article
Synthesis and structure–activity relationship of novel conformationally restricted analogues of serotonin as 5-HT 6 receptor ligands
Nirogi, Ramakrishna V.S., Kambhampati, Ramasastri, Kothmirkar, Prabhakar, Konda, Jagadishbabu, Bandyala, Thrinath Reddy, Gudla, Parandhama, Arepalli, Sobhanadri, Gangadasari, Narasimhareddy P., Shinde, Anil K., Deshpande, Amol D., Dwarampudi, Adireddy, Chindhe, Anil K., Dubey, Pramod Kumar
Published in Journal of enzyme inhibition and medicinal chemistry (01.06.2012)
Published in Journal of enzyme inhibition and medicinal chemistry (01.06.2012)
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Journal Article