Search Results - "KAMADA, NOBORU" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

An Efficient Method for Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-like Cells Retaining Drug Metabolizing Activity

An Efficient Method for Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-like Cells Retaining Drug Metabolizing Activity

by Kondo, Yuki, Iwao, Takahiro, Nakamura, Katsunori, Sasaki, Takamitsu, Takahashi, Shogo, Kamada, Noboru, Matsubara, Tsutomu, Gonzalez, Frank J., Akutsu, Hidenori, Miyagawa, Yoshitaka, Okita, Hajime, Kiyokawa, Nobutaka, Toyoda, Masashi, Umezawa, Akihiro, Nagata, Kiyoshi, Matsunaga, Tamihide, Ohmori, Shigeru
Published in Drug metabolism and pharmacokinetics (2014)

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Differentiation of Monkey Embryonic Stem Cells to Hepatocytes by Feeder-Free Dispersion Culture and Expression Analyses of Cytochrome P450 Enzymes Responsible for Drug Metabolism

Differentiation of Monkey Embryonic Stem Cells to Hepatocytes by Feeder-Free Dispersion Culture and Expression Analyses of Cytochrome P450 Enzymes Responsible for Drug Metabolism

by Maruyama, Junya, Matsunaga, Tamihide, Yamaori, Satoshi, Sakamoto, Sakae, Kamada, Noboru, Nakamura, Katsunori, Kikuchi, Shinji, Ohmori, Shigeru
Published in Biological & pharmaceutical bulletin (01.02.2013)

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Synthesis and c-Src inhibitory activity of imidazo[1,5- a]pyrazine derivatives as an agent for treatment of acute ischemic stroke

Synthesis and c-Src inhibitory activity of imidazo[1,5- a]pyrazine derivatives as an agent for treatment of acute ischemic stroke

by Mukaiyama, Harunobu, Nishimura, Toshihiro, Kobayashi, Satoko, Ozawa, Tomonaga, Kamada, Noboru, Komatsu, Yoshimitsu, Kikuchi, Shinji, Oonota, Hideki, Kusama, Hiroshi
Published in Bioorganic & medicinal chemistry (15.01.2007)

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Evaluation of Human Embryonic Stem Cell-derived Hepatocyte-like Cells for Detection of CYP1A Inducers

Evaluation of Human Embryonic Stem Cell-derived Hepatocyte-like Cells for Detection of CYP1A Inducers

by Tsuchiya, Hiroyuki, Matsunaga, Tamihide, Aikawa, Kaori, Kamada, Noboru, Nakamura, Katsunori, Ichikawa, Hinako, Sasaki, Katsunori, Ohmori, Shigeru
Published in DRUG METABOLISM AND PHARMACOKINETICS (2012)

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Discovery of Novel 2-Anilinopyrazolo[1,5-a]pyrimidine Derivatives as c-Src Kinase Inhibitors for the Treatment of Acute Ischemic Stroke

Discovery of Novel 2-Anilinopyrazolo[1,5-a]pyrimidine Derivatives as c-Src Kinase Inhibitors for the Treatment of Acute Ischemic Stroke

by Mukaiyama, Harunobu, Nishimura, Toshihiro, Shiohara, Hiroaki, Kobayashi, Satoko, Komatsu, Yoshimitsu, Kikuchi, Shinji, Tsuji, Eiichi, Kamada, Noboru, Ohnota, Hideki, Kusama, Hiroshi
Published in Chemical & Pharmaceutical Bulletin (01.06.2007)

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The Advantages of the Ussing Chamber in Drug Absorption Studies

The Advantages of the Ussing Chamber in Drug Absorption Studies

by Gotoh, Yasumasa, Kamada, Noboru, Momose, Denichi
Published in Journal of biomolecular screening (01.08.2005)

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Differentiation of Monkey Embryonic Stem Cells to Hepatocytes by Feeder-Free Dispersion Culture and Expression Analyses of Cytochrome P450 Enzymes Responsible for Drug Metabolism

Differentiation of Monkey Embryonic Stem Cells to Hepatocytes by Feeder-Free Dispersion Culture and Expression Analyses of Cytochrome P450 Enzymes Responsible for Drug Metabolism

by Junya Maruyama, Tamihide Matsunaga, Satoshi Yamaori, Sakae Sakamoto, Noboru Kamada, Katsunori Nakamura, Shinji Kikuchi, Shigeru Ohmori
Published in Biological and Pharmaceutical Bulletin (01.02.2013)

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Journal Article

Fourteen Chamigrane Derivatives from a Red Alga, Laurencia nidifica

Fourteen Chamigrane Derivatives from a Red Alga, Laurencia nidifica

by Kimura, Junji, Kamada, Noboru, Tsujimoto, Yoshikazu
Published in Bulletin of the Chemical Society of Japan (01.02.1999)

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Journal Article

An Efficient Method for Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-like Cells Retaining Drug Metabolizing Activity

An Efficient Method for Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-like Cells Retaining Drug Metabolizing Activity

by Yuki KONDO, Takahiro IWAO, Katsunori NAKAMURA, Takamitsu SASAKI, Shogo TAKAHASHI, Noboru KAMADA, Tsutomu MATSUBARA, Frank J.GONZALEZ, Hidenori AKUTSU, Yoshitaka MIYAGAWA, Hajime OKITA, Nobutaka KIYOKAWA, Masashi TOYODA, Akihiro UMEZAWA, Kiyoshi NAGATA, Tamihide MATSUNAGA, Shigeru OHMORI
Published in DRUG METABOLISM AND PHARMACOKINETICS (25.06.2014)

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Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects

Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects

by Kobayashi, Jun-ichi, Hirasawa, Hideaki, Fujimori, Yoshikazu, Nakanishi, Osamu, Kamada, Noboru, Ikeda, Tetsuya, Yamamoto, Akitoshi, Kanbe, Hiroki
Published in Bioorganic & medicinal chemistry (15.01.2021)

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Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor

Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor

by Shimizu, Kazuo, Fujikura, Hideki, Fushimi, Nobuhiko, Nishimura, Toshihiro, Tatani, Kazuya, Katsuno, Kenji, Fujimori, Yoshikazu, Watanabe, Shinjiro, Hiratochi, Masahiro, Nakabayashi, Takeshi, Kamada, Noboru, Arakawa, Koichi, Hikawa, Hidemasa, Azumaya, Isao, Isaji, Masayuki
Published in Bioorganic & medicinal chemistry (15.03.2021)

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Synthesis and optimization of novel α-phenylglycinamides as selective TRPM8 antagonists

Synthesis and optimization of novel α-phenylglycinamides as selective TRPM8 antagonists

by Kobayashi, Jun-ichi, Hirasawa, Hideaki, Ozawa, Tetsuji, Ozawa, Tomonaga, Takeda, Hiroo, Fujimori, Yoshikazu, Nakanishi, Osamu, Kamada, Noboru, Ikeda, Tetsuya
Published in Bioorganic & medicinal chemistry (15.01.2017)

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Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides

Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides

by Hiratochi, Masahiro, Tatani, Kazuya, Shimizu, Kazuo, Kuramochi, Yu, Kikuchi, Norihiko, Kamada, Noboru, Itoh, Fumiaki, Isaji, Masayuki
Published in European journal of pharmacology (05.09.2012)

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Interspecies differences in gastrointestinal physiology affecting the in vivo performance of oral pharmaceutical solid dosage forms

Interspecies differences in gastrointestinal physiology affecting the in vivo performance of oral pharmaceutical solid dosage forms

by Kambayashi, Atsushi, Murano, Mika, Imai, Shunji, Miyata, Kenichi, Sugita, Katsuji, Fujii, Yoshimine, Kinoshita, Masahiro, Nomura, Akinori, Kimoto, Takahiro, Miyazaki, Yoshikazu, Sakakibara, Hiroyuki, Kakuda, Sahoe, Tsujimoto, Takuya, Fujita, Yuu, Kano, Mayumi, Nakamura, Hideaki, Akaogi, Seiichirou, Honda, Makoto, Anraku, Makoto, Kamada, Noboru, Ohta, Kotoe, Uchida, Masashi, Kataoka, Makoto, Kikuchi, Hiroshi, Yamashita, Shinji, Kondo, Hiromu
Published in Journal of drug delivery science and technology (01.01.2022)

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Development and validation of an LC-MS/MS method for simultaneously determining doxapram and keto-doxapram in human serum

Development and validation of an LC-MS/MS method for simultaneously determining doxapram and keto-doxapram in human serum

by Suzuki, Yuki, Kamada, Noboru, Ohno, Hitoshi, Abe, Yoshikazu, Endo, Takuro, Kobayashi, Mamoru
Published in Bioanalysis (01.03.2017)

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Population pharmacokinetics of doxapram in low-birth-weight Japanese infants with apnea

Population pharmacokinetics of doxapram in low-birth-weight Japanese infants with apnea

by Ogawa, Yuki, Irikura, Mitsuru, Kobaru, Yuka, Tomiyasu, Mayu, Kochiyama, Yoshie, Uriu, Mamiko, Ishitsuka, Yoichi, Kondo, Yuki, Yukawa, Eiji, Kamada, Noboru, Ohno, Hitoshi, Yamazaki, Toshio, Irie, Tetsumi
Published in European journal of pediatrics (01.04.2015)

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Novel pyrazolo[1,5-a]pyrimidines as c-Src kinase inhibitors that reduce IKr channel blockade

Novel pyrazolo[1,5-a]pyrimidines as c-Src kinase inhibitors that reduce IKr channel blockade

by MUKAIYAMA, Harunobu, NISHIMURA, Toshihiro, KOBAYASHI, Satoko, KOMATSU, Yoshimitsu, KIKUCHI, Shinji, OZAWA, Tomonaga, KAMADA, Noboru, OHNOTA, Hideki
Published in Bioorganic & medicinal chemistry (15.01.2008)

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Journal Article

Novel pyrazolo[1,5- a]pyrimidines as c-Src kinase inhibitors that reduce I Kr channel blockade

Novel pyrazolo[1,5- a]pyrimidines as c-Src kinase inhibitors that reduce I Kr channel blockade

by Mukaiyama, Harunobu, Nishimura, Toshihiro, Kobayashi, Satoko, Komatsu, Yoshimitsu, Kikuchi, Shinji, Ozawa, Tomonaga, Kamada, Noboru, Ohnota, Hideki
Published in Bioorganic & medicinal chemistry (15.01.2008)

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Structure–activity relationship studies of 4-benzyl-1H-pyrazol-3-yl β-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia

Structure–activity relationship studies of 4-benzyl-1H-pyrazol-3-yl β-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia

by Fushimi, Nobuhiko, Fujikura, Hideki, Shiohara, Hiroaki, Teranishi, Hirotaka, Shimizu, Kazuo, Yonekubo, Shigeru, Ohno, Kohsuke, Miyagi, Takashi, Itoh, Fumiaki, Shibazaki, Toshihide, Tomae, Masaki, Ishikawa-Takemura, Yukiko, Nakabayashi, Takeshi, Kamada, Noboru, Ozawa, Tomonaga, Kobayashi, Susumu, Isaji, Masayuki
Published in Bioorganic & medicinal chemistry (15.11.2012)

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Journal Article

Design, synthesis, and structure–activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl β-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)

Design, synthesis, and structure–activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl β-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)

by Fushimi, Nobuhiko, Teranishi, Hirotaka, Shimizu, Kazuo, Yonekubo, Shigeru, Ohno, Kohsuke, Miyagi, Takashi, Itoh, Fumiaki, Shibazaki, Toshihide, Tomae, Masaki, Ishikawa-Takemura, Yukiko, Nakabayashi, Takeshi, Kamada, Noboru, Yamauchi, Yuji, Kobayashi, Susumu, Isaji, Masayuki
Published in Bioorganic & medicinal chemistry (01.02.2013)

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