Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis
Lauwaet, Tineke, Miyamoto, Yukiko, Ihara, Sozaburo, Le, Christine, Kalisiak, Jarosław, Korthals, Keith A, Ghassemian, Majid, Smith, Diane K, Sharpless, K Barry, Fokin, Valery V, Eckmann, Lars
Published in PLoS neglected tropical diseases (01.04.2020)
Published in PLoS neglected tropical diseases (01.04.2020)
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Journal Article
Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity
Miyamoto, Yukiko, Kalisiak, Jarosław, Korthals, Keith, Lauwaet, Tineke, Cheung, Dae Young, Lozano, Ricardo, Cobo, Eduardo R., Upcroft, Peter, Upcroft, Jacqueline A., Berg, Douglas E., Gillin, Frances D., Fokin, Valery V., Sharpless, K. Barry, Eckmann, Lars
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2013)
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Journal Article
Correlating the Transcriptome, Proteome, and Metabolome in the Environmental Adaptation of a Hyperthermophile
Trauger, Sunia A, Kalisak, Ewa, Kalisiak, Jaroslaw, Morita, Hirotoshi, Weinberg, Michael V, Menon, Angeli Lal, Poole II, Farris L, Adams, Michael W. W, Siuzdak, Gary
Published in Journal of proteome research (01.03.2008)
Published in Journal of proteome research (01.03.2008)
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Journal Article
Nonquaternary Reactivators for Organophosphate-Inhibited Cholinesterases
Kalisiak, Jarosław, Ralph, Erik C, Cashman, John R
Published in Journal of medicinal chemistry (12.01.2012)
Published in Journal of medicinal chemistry (12.01.2012)
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Journal Article
Amidine−Oximes: Reactivators for Organophosphate Exposure
Kalisiak, Jarosław, Ralph, Erik C, Zhang, Jun, Cashman, John R
Published in Journal of medicinal chemistry (12.05.2011)
Published in Journal of medicinal chemistry (12.05.2011)
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Journal Article
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases
Maček Hrvat, Nikolina, Kalisiak, Jarosław, Šinko, Goran, Radić, Zoran, Sharpless, K. Barry, Taylor, Palmer, Kovarik, Zrinka
Published in Toxicology letters (15.03.2020)
Published in Toxicology letters (15.03.2020)
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Journal Article
Reversal of Tabun Toxicity Enabled by a Triazole‐Annulated Oxime Library—Reactivators of Acetylcholinesterase
Kovarik, Zrinka, Kalisiak, Jarosław, Hrvat, Nikolina Maček, Katalinić, Maja, Zorbaz, Tamara, Žunec, Suzana, Green, Carol, Radić, Zoran, Fokin, Valery V., Sharpless, K. Barry, Taylor, Palmer
Published in Chemistry : a European journal (15.03.2019)
Published in Chemistry : a European journal (15.03.2019)
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Journal Article
Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase
Kovarik, Zrinka, Maček Hrvat, Nikolina, Kalisiak, Jarosław, Katalinić, Maja, Sit, Rakesh K., Zorbaz, Tamara, Radić, Zoran, Fokin, Valery V., Sharpless, K. Barry, Taylor, Palmer
Published in Toxicology and applied pharmacology (01.06.2019)
Published in Toxicology and applied pharmacology (01.06.2019)
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Journal Article
Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia
Kim, Wan Jung, Korthals, Keith A, Li, Suhua, Le, Christine, Kalisiak, Jarosław, Sharpless, K Barry, Fokin, Valery V, Miyamoto, Yukiko, Eckmann, Lars
Published in Antimicrobial agents and chemotherapy (01.06.2017)
Published in Antimicrobial agents and chemotherapy (01.06.2017)
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Journal Article
Oxime-assisted Acetylcholinesterase Catalytic Scavengers of Organophosphates That Resist Aging
Cochran, Rory, Kalisiak, Jarosław, Küçükkılınç, Tuba, Radić, Zoran, Garcia, Edzna, Zhang, Limin, Ho, Kwok-Yiu, Amitai, Gabriel, Kovarik, Zrinka, Fokin, Valery V., Sharpless, K. Barry, Taylor, Palmer
Published in The Journal of biological chemistry (26.08.2011)
Published in The Journal of biological chemistry (26.08.2011)
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Journal Article
Development of a Concise Process for the Synthesis of the Azaindazole Core of the CD73 Inhibitor AB680
Yin, Xiaopeng, Song, Zhiguo Jake, Kalisiak, Jaroslaw, Tripp, Jonathan C., Lei, Xiao, Li, Hongfeng, Zhang, Aimin
Published in Organic process research & development (19.05.2023)
Published in Organic process research & development (19.05.2023)
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Journal Article
Identification of a New Endogenous Metabolite and the Characterization of Its Protein Interactions through an Immobilization Approach
Kalisiak, Jarosław, Trauger, Sunia A, Kalisiak, Ewa, Morita, Hirotoshi, Fokin, Valery V, Adams, Mike W. W, Sharpless, K. Barry, Siuzdak, Gary
Published in Journal of the American Chemical Society (14.01.2009)
Published in Journal of the American Chemical Society (14.01.2009)
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Journal Article
Discovery of AB680: A Potent and Selective Inhibitor of CD73
Lawson, Kenneth V, Kalisiak, Jaroslaw, Lindsey, Erick A, Newcomb, Eric T, Leleti, Manmohan Reddy, Debien, Laurent, Rosen, Brandon R, Miles, Dillon H, Sharif, Ehesan U, Jeffrey, Jenna L, Tan, Joanne B. L, Chen, Ada, Zhao, Sharon, Xu, Guifen, Fu, Lijuan, Jin, Lixia, Park, Tim W, Berry, Wade, Moschütz, Susanne, Scaletti, Emma, Sträter, Norbert, Walker, Nigel P, Young, Stephen W, Walters, Matthew J, Schindler, Uli, Powers, Jay P
Published in Journal of medicinal chemistry (22.10.2020)
Published in Journal of medicinal chemistry (22.10.2020)
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Journal Article
Targeting CD73 with AB680 (Quemliclustat), a Novel and Potent Small-Molecule CD73 Inhibitor, Restores Immune Functionality and Facilitates Antitumor Immunity
Piovesan, Dana, Tan, Joanne B L, Becker, Annette, Banuelos, Jesus, Narasappa, Nell, DiRenzo, Daniel, Zhang, Kristen, Chen, Ada, Ginn, Elaine, Udyavar, Akshata R, Yin, Fangfang, Paprcka, Susan L, Purandare, Bhamini, Park, Timothy W, Kimura, Nikki, Kalisiak, Jaroslaw, Young, Stephen W, Powers, Jay P, Schindler, Uli, Sivick, Kelsey E, Walters, Matthew J
Published in Molecular cancer therapeutics (01.06.2022)
Published in Molecular cancer therapeutics (01.06.2022)
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Journal Article
Wnt Inhibition Correlates with Human Embryonic Stem Cell Cardiomyogenesis: A Structure–Activity Relationship Study Based on Inhibitors for the Wnt Response
Lanier, Marion, Schade, Dennis, Willems, Erik, Tsuda, Masanao, Spiering, Sean, Kalisiak, Jaroslaw, Mercola, Mark, Cashman, John R
Published in Journal of medicinal chemistry (26.01.2012)
Published in Journal of medicinal chemistry (26.01.2012)
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Journal Article
Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors
Sharif, Ehesan U., Kalisiak, Jaroslaw, Lawson, Kenneth, Miles, Dillon H., Newcomb, Eric, Lindsey, Erick A., Rosen, Brandon R., Debien, Laurent P. P., Chen, Ada, Zhao, Xiaoning, Young, Stephen W., Walker, Nigel P., Straeter, Norbert, Scaletti, Emma R., Jin, Lixia, Xu, Guifen, Leleti, Manmohan R., Powers, Jay P.
Published in Journal of medicinal chemistry (14.01.2021)
Published in Journal of medicinal chemistry (14.01.2021)
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Journal Article
5 PROCESSES AND INTERMEDIATES IN THE PREPARATION OF C5aR ANTAGONISTS
PUNNA SREENIVAS, TANAKA HIROKO, FAN PINGCHEN, KALISIAK JAROSLAW, POWERS JAY, ZHANG PENGLIE, KRASINSKI ANTONI, LUI REBECCA
Year of Publication 27.10.2023
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Year of Publication 27.10.2023
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