Synthesis of substituted 5[ H]phenanthridin-6-ones as potent poly(ADP-ribose)polymerase-1 (PARP1) inhibitors
Li, Jia-He, Serdyuk, Larisa, Ferraris, Dana V., Xiao, Ge, Tays, Kevin L., Kletzly, Paul W., Li, Weixing, Lautar, Susan, Zhang, Jie, Kalish, Vincent J.
Published in Bioorganic & medicinal chemistry letters (09.07.2001)
Published in Bioorganic & medicinal chemistry letters (09.07.2001)
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Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease
Kaldor, Stephen W, Kalish, Vincent J, Davies, Jay F, Shetty, Bhasker V, Fritz, James E, Appelt, Krzysztof, Burgess, Jeffrey A, Campanale, Kristina M, Chirgadze, Nickolay Y, Clawson, David K, Dressman, Bruce A, Hatch, Steven D, Khalil, Deborah A, Kosa, Maha B, Lubbehusen, Penny P, Muesing, Mark A, Patick, Amy K, Reich, Siegfried H, Su, Kenneth S, Tatlock, John H
Published in Journal of medicinal chemistry (21.11.1997)
Published in Journal of medicinal chemistry (21.11.1997)
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Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
Kissinger, Charles R, Parge, Hans E, Knighton, Daniel R, Lewis, Cristina T, Pelletier, Laura A, Tempczyk, Anna, Kalish, Vincent J, Tucker, Kathleen D, Showalter, Richard E, Moomaw, Ellen W, Gastinel, Louis N, Habuka, Noriyuki, Chen, Xinghai, Maldonado, Fausto, Barker, John E, Bacquet, Russell, Villafranca, J. Ernest
Published in Nature (London) (07.12.1995)
Published in Nature (London) (07.12.1995)
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Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. part 4: Biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of ischemic injuries
Ferraris, Dana, Ficco, Rica Pargas, Dain, David, Ginski, Mark, Lautar, Susan, Lee-Wisdom, Kathy, Liang, Shi, Lin, Qian, Lu, May X.-C, Morgan, Lisa, Thomas, Bert, Williams, Lawrence R, Zhang, Jie, Zhou, Yinong, Kalish, Vincent J
Published in Bioorganic & medicinal chemistry (15.08.2003)
Published in Bioorganic & medicinal chemistry (15.08.2003)
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One-pot synthesis of protected prostaglandins from alkynes and cyclopentenones. In situ generation of higher order cyanocuprates derived from alkenylzirconium intermediates
Babiak, Kevin A, Behling, James R, Dygos, John H, McLaughlin, Kathleen T, Ng, John S, Kalish, Vincent J, Kramer, Steven W, Shone, Robert L
Published in Journal of the American Chemical Society (01.09.1990)
Published in Journal of the American Chemical Society (01.09.1990)
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Structure-activity relationships within a series of caspase inhibitors: Effect of leaving group modifications
ULLMAN, Brett R, AJA, Teresa, ROGGO, Silvio P, SAYERS, Robert O, SCHMITZ, Albert, TERNANSKY, Robert J, TOMASELLI, Kevin J, WU, Joe C, DECKWERTH, Thomas L, DIAZ, Jose-Luis, HERRMANN, Julia, KALISH, Vincent J, KARANEWSKY, Donald S, MEDUNA, Steven P, NALLEY, Kip, ROBINSON, Edward D
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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Structure–activity relationships within a series of caspase inhibitors. Part 2: Heterocyclic warheads
Ullman, Brett R., Aja, Teresa, Chen, Ning, Diaz, Jose-Luis, Gu, Xin, Herrmann, Julia, Kalish, Vincent J., Karanewsky, Donald S., Kodandapani, Lalitha, Krebs, Joseph J., Linton, Steven D., Meduna, Steven P., Nalley, Kip, Robinson, Edward D., Roggo, Silvio P., Sayers, Robert O., Schmitz, Albert, Ternansky, Robert J., Tomaselli, Kevin J., Wu, Joe C.
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
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Acyl dipeptides as reversible caspase inhibitors. Part 2: Further optimization
LINTON, Steven D, KARANEWSKY, Donald S, WU, Joe C, PHAM, Brian, KODANDAPANI, Lalitha, SMIDT, Robert, DIAZ, Jose-Luis, FRITZ, Lawrence C, VON KROSIGK, U, ROGGO, Silvio, SCHMITZ, Albert, TOMASELLI, Kevin J, TERNANSKY, Robert J, NING CHEN, GUO, Xian, JAHANGIRI, Kathy G, KALISH, Vincent J, MEDUNA, Steven P, ROBINSON, Edward D, ULLMAN, Brett R
Published in Bioorganic & medicinal chemistry letters (21.10.2002)
Published in Bioorganic & medicinal chemistry letters (21.10.2002)
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Journal Article
Structure-Based Design of Novel, Urea-Containing FKBP12 Inhibitors
Dragovich, Peter S, Barker, John E, French, Judy, Imbacuan, Michael, Kalish, Vincent J, Kissinger, Charles R, Knighton, Daniel R, Lewis, Cristina T, Moomaw, Ellen W, Parge, Hans E, Pelletier, Laura A. K, Prins, Thomas J, Showalter, Richard E, Tatlock, John H, Tucker, Kathleen D, Villafranca, J. Ernest
Published in Journal of medicinal chemistry (26.04.1996)
Published in Journal of medicinal chemistry (26.04.1996)
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First-in-Class Pan Caspase Inhibitor Developed for the Treatment of Liver Disease
Linton, Steven D, Aja, Teresa, Armstrong, Robert A, Bai, Xu, Chen, Long-Shiuh, Chen, Ning, Ching, Brett, Contreras, Patricia, Diaz, Jose-Luis, Fisher, Craig D, Fritz, Lawrence C, Gladstone, Patricia, Groessl, Todd, Gu, Xin, Herrmann, Julia, Hirakawa, Brad P, Hoglen, Niel C, Jahangiri, Kathy G, Kalish, Vincent J, Karanewsky, Donald S, Kodandapani, Lalitha, Krebs, Joseph, McQuiston, Jeff, Meduna, Steven P, Nalley, Kip, Robinson, Edward D, Sayers, Robert O, Sebring, Kristen, Spada, Alfred P, Ternansky, Robert J, Tomaselli, Kevin J, Ullman, Brett R, Valentino, Karen L, Weeks, Suzanne, Winn, David, Wu, Joe C, Yeo, Pauline, Zhang, Cheng-zhi
Published in Journal of medicinal chemistry (03.11.2005)
Published in Journal of medicinal chemistry (03.11.2005)
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Approaches to the total synthesis of the antitumor antibiotic echinosporin
Kinsella, Mary A, Kalish, Vincent J, Weinreb, Steven M
Published in Journal of organic chemistry (1990)
Published in Journal of organic chemistry (1990)
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