Design and synthesis of HIV-1 protease inhibitors for a long-acting injectable drug application
Kesteleyn, Bart, Amssoms, Katie, Schepens, Wim, Hache, Geerwin, Verschueren, Wim, Van De Vreken, Wim, Rombauts, Klara, Meurs, Greet, Sterkens, Patrick, Stoops, Bart, Baert, Lieven, Austin, Nigel, Wegner, Jörg, Masungi, Chantal, Dierynck, Inge, Lundgren, Stina, Jönsson, Daniel, Parkes, Kevin, Kalayanov, Genadiy, Wallberg, Hans, Rosenquist, Åsa, Samuelsson, Bertil, Van Emelen, Kristof, Thuring, Jan Willem
Published in Bioorganic & medicinal chemistry letters (01.01.2013)
Published in Bioorganic & medicinal chemistry letters (01.01.2013)
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Discovery of β-d-2′-deoxy-2′-dichlorouridine nucleotide prodrugs as potent inhibitors of hepatitis C virus replication
Pinho, Pedro, Kalayanov, Genadiy, Westerlind, Hans, Rosenquist, Åsa, Wähling, Horst, Sund, Christian, Almeida, Maria, Ayesa, Susana, Tejbrant, Jan, Targett-Adams, Paul, Eneroth, Anders, Lindqvist, Annelie
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
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The Design, Synthesis, and Antiviral Activity of Monofluoro and Difluoro Analogues of 4′-Azidocytidine against Hepatitis C Virus Replication: The Discovery of 4′-Azido-2′-deoxy-2′-fluorocytidine and 4′-Azido-2′-dideoxy-2′,2′-difluorocytidine
Smith, David B, Kalayanov, Genadiy, Sund, Christian, Winqvist, Anna, Maltseva, Tatiana, Leveque, Vincent J.-P, Rajyaguru, Sonal, Pogam, Sophie Le, Najera, Isabel, Benkestock, Kurt, Zhou, Xiao-Xiong, Kaiser, Ann C, Maag, Hans, Cammack, Nick, Martin, Joseph A, Swallow, Steven, Johansson, Nils Gunnar, Klumpp, Klaus, Smith, Mark
Published in Journal of medicinal chemistry (14.05.2009)
Published in Journal of medicinal chemistry (14.05.2009)
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Journal Article
2′-Deoxy-4′-azido Nucleoside Analogs Are Highly Potent Inhibitors of Hepatitis C Virus Replication Despite the Lack of 2′-α-Hydroxyl Groups
Klumpp, Klaus, Kalayanov, Genadiy, Ma, Han, Le Pogam, Sophie, Leveque, Vincent, Jiang, Wen-Rong, Inocencio, Nicole, De Witte, Anniek, Rajyaguru, Sonal, Tai, Ezra, Chanda, Sushmita, Irwin, Michael R., Sund, Christian, Winqist, Anna, Maltseva, Tatiana, Eriksson, Staffan, Usova, Elena, Smith, Mark, Alker, Andre, Najera, Isabel, Cammack, Nick, Martin, Joseph A., Johansson, Nils Gunnar, Smith, David B.
Published in The Journal of biological chemistry (25.01.2008)
Published in The Journal of biological chemistry (25.01.2008)
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The Design, Synthesis, and Antiviral Activity of 4′-Azidocytidine Analogues against Hepatitis C Virus Replication: The Discovery of 4′-Azidoarabinocytidine
Smith, David B, Kalayanov, Genadiy, Sund, Christian, Winqvist, Anna, Pinho, Pedro, Maltseva, Tatiana, Morisson, Veronique, Leveque, Vincent, Rajyaguru, Sonal, Pogam, Sophie Le, Najera, Isabel, Benkestock, Kurt, Zhou, Xiao-Xiong, Maag, Hans, Cammack, Nick, Martin, Joseph A, Swallow, Steven, Johansson, Nils Gunnar, Klumpp, Klaus, Smith, Mark
Published in Journal of medicinal chemistry (08.01.2009)
Published in Journal of medicinal chemistry (08.01.2009)
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Journal Article
Nicotine hapten structure, antibody selectivity and effect relationships: Results from a nicotine vaccine screening procedure
de Villiers, Sabina H.L, Lindblom, Nina, Kalayanov, Genadiy, Gordon, Sandra, Baraznenok, Ivan, Malmerfelt, Anna, Marcus, Monica M, Johansson, Anette M, Svensson, Torgny H
Published in Vaccine (02.03.2010)
Published in Vaccine (02.03.2010)
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Design and synthesis of potent hydroxyethylamine (HEA) BACE-1 inhibitors carrying prime side 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templates
Sund, Christian, Belda, Oscar, Borkakoti, Neera, Lindberg, Jimmy, Derbyshire, Dean, Vrang, Lotta, Hamelink, Elizabeth, Åhgren, Cathrine, Woestenenk, Esmeralda, Wikström, Kristina, Eneroth, Anders, Lindström, Erik, Kalayanov, Genadiy
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
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Journal Article
Discovery of 4′-azido-2′-deoxy-2′-C-methyl cytidine and prodrugs thereof: A potent inhibitor of Hepatitis C virus replication
Nilsson, Magnus, Kalayanov, Genadiy, Winqvist, Anna, Pinho, Pedro, Sund, Christian, Zhou, Xiao-Xiong, Wähling, Horst, Belfrage, Anna-Karin, Pelcman, Michael, Agback, Tatiana, Benckestock, Kurt, Wikström, Kristina, Boothee, Mirva, Lindqvist, Anneli, Rydegård, Christina, Jonckers, Tim H.M., Vandyck, Koen, Raboisson, Pierre, Lin, Tse-I, Lachau-Durand, Sophie, de Kock, Herman, Smith, David B., Martin, Joseph A., Klumpp, Klaus, Simmen, Kenneth, Vrang, Lotta, Terelius, Ylva, Samuelsson, Bertil, Rosenquist, Åsa, Johansson, Nils Gunnar
Published in Bioorganic & medicinal chemistry letters (01.05.2012)
Published in Bioorganic & medicinal chemistry letters (01.05.2012)
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Journal Article
2â²-Deoxy-4â²-azido Nucleoside Analogs Are Highly Potent Inhibitors of Hepatitis C Virus Replication Despite the Lack of 2â²-α-Hydroxyl Groups
Klaus Klumpp, Genadiy Kalayanov, Han Ma, Sophie Le Pogam, Vincent Leveque, Wen-Rong Jiang, Nicole Inocencio, Anniek De Witte, Sonal Rajyaguru, Ezra Tai, Sushmita Chanda, Michael R. Irwin, Christian Sund, Anna Winqist, Tatiana Maltseva, Staffan Eriksson, Elena Usova, Mark Smith, Andre Alker, Isabel Najera, Nick Cammack, Joseph A. Martin, Nils Gunnar Johansson, David B. Smith
Published in The Journal of biological chemistry (25.01.2008)
Published in The Journal of biological chemistry (25.01.2008)
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Journal Article
Different Incorporation Efficiencies for Nucleotide Analogs During HCV Polymerase RNA Synthesis Initiation and Elongation Phases
Ma, Han, Inocencio, Nicole, Leveque, Vincent, Kalayanov, Genadiy, Smith, David, Cammack, Nick, Johansson, Nils Gunnar, Klumpp, Klaus
Published in Antiviral research (01.05.2008)
Published in Antiviral research (01.05.2008)
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Journal Article
Active immunisation against nicotine blocks the reward facilitating effects of nicotine and partially prevents nicotine withdrawal in the rat as measured by dopamine output in the nucleus accumbens, brain reward thresholds and somatic signs
Lindblom, Nina, de Villiers, Sabina H L, Semenova, Svetlana, Kalayanov, Genadiy, Gordon, Sandra, Schilström, Björn, Johansson, Anette M, Markou, Athina, Svensson, Torgny H
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.11.2005)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.11.2005)
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Journal Article
2′-Deoxy-nucleoside Analogs can be Potent Dual Inhibitors of HCV and HIV Replication with Selectivity against Human Polymerases
Klumpp, Klaus, Su, Guoping, Leveque, Vincent, Deval, Jerome, Heilek, Gabrielle, Rajyaguru, Sonal, Li, Yu, Hang, Julie Q., Ma, Han, Inocencio, Nicole, Kalayanov, Genadiy, Winqvist, Anna, Smith, David B., Cammack, Nick, Johansson, Nils Gunnar, Najera, Isabel
Published in Antiviral research (01.05.2009)
Published in Antiviral research (01.05.2009)
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Journal Article
Active immunization against nicotine alters the distribution of nicotine but not the metabolism to cotinine in the rat
de Villiers, Sabina H L, Lindblom, Nina, Kalayanov, Genadiy, Gordon, Sandra, Johansson, Anette M, Svensson, Torgny H
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.10.2004)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.10.2004)
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