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Published in PloS one (04.11.2015)
Published in PloS one (04.11.2015)
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Identification of a novel long-acting 4’-modified nucleoside reverse transcriptase inhibitor against HBV
Higashi-Kuwata, Nobuyo, Hayashi, Sanae, Kumamoto, Hiroki, Ogata-Aoki, Hiromi, Das, Debananda, Venzon, David, Hattori, Shin-ichiro, Bulut, Haydar, Hashimoto, Mai, Otagiri, Masaki, Takamune, Nobutoki, Kishimoto, Naoki, Davis, David A., Misumi, Shogo, Kakuni, Masakazu, Tanaka, Yasuhito, Mitsuya, Hiroaki
Published in Journal of hepatology (01.05.2021)
Published in Journal of hepatology (01.05.2021)
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Chimeric mice with humanized livers: a unique tool for in vivo and in vitro enzyme induction studies
Kakuni, Masakazu, Yamasaki, Chihiro, Tachibana, Asato, Yoshizane, Yasumi, Ishida, Yuji, Tateno, Chise
Published in International journal of molecular sciences (20.12.2013)
Published in International journal of molecular sciences (20.12.2013)
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Lipoprotein profile and lipid metabolism of PXB-cells®, human primary hepatocytes from liver-humanized mice: proposal of novel in vitro system for screening anti-lipidemic drugs
HATA, Keishi, Sayaka, TOMATSU, TAKAHASHI, Masaki, SASAKI, Akira, UMEKAWA, Yui, MIYASHITA, Kazuya, OGURA, Kazumi, TOSHIMA, Gen, MAEDA, Masahiro, TAKAHASHI, Junichiro, KAKUNI, Masakazu
Published in Biomedical Research (01.01.2020)
Published in Biomedical Research (01.01.2020)
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In Vitro Evaluation of Cytochrome P450 and Glucuronidation Activities in Hepatocytes Isolated from Liver-Humanized Mice
Yamasaki, Chihiro, Kataoka, Miho, Kato, Yumiko, Kakuni, Masakazu, Usuda, Sadakazu, Ohzone, Yoshihiro, Matsuda, Sunao, Adachi, Yasuhisa, Ninomiya, Shin-ichi, Itamoto, Toshiyuki, Asahara, Toshimasa, Yoshizato, Katsutoshi, Tateno, Chise
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2010)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2010)
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Hepatitis B Virus Therapeutic Agent ARB-1740 Has Inhibitory Effect on Hepatitis Delta Virus in a New Dually-Infected Humanized Mouse Model
Ye, Xin, Tateno, Chise, Thi, Emily P, Kakuni, Masakazu, Snead, Nicholas M, Ishida, Yuji, Barnard, Trisha R, Sofia, Michael J, Shimada, Takashi, Lee, Amy C. H
Published in ACS infectious diseases (10.05.2019)
Published in ACS infectious diseases (10.05.2019)
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Role of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis
Uchii, Masako, Tamura, Tadafumi, Suda, Toshio, Kakuni, Masakazu, Tanaka, Akira, Miki, Ichiro
Published in Arthritis research & therapy (01.01.2008)
Published in Arthritis research & therapy (01.01.2008)
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In vivo and in vitro HBV infection model using chimeric mice with humanized livers
Ishida, Yuji, Yokomichi, Hiroshi, Kakuni, Masakazu, Tateno, Chise
Published in Nihon rinshō (01.12.2015)
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Published in Nihon rinshō (01.12.2015)
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THU319 - PXB-cells for the study of lipid metabolism: robust and human-specific lipid profile in human hepatocytes freshly isolated from chimeric mice with humanized liver
Takahashi, Masaki, Kakuni, Masakazu, Tomatsu, Sayaka, Hata, Keishi
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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PXB-cells for the study of lipid metabolism: robust and human-specific lipid profile in human hepatocytes freshly isolated from chimeric mice with humanized liver
Takahashi, Masaki, Kakuni, Masakazu, Tomatsu, Sayaka, Hata, Keishi
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Organic Anion-Transporting Polypeptide (OATP)-Mediated Drug-Drug Interaction Study between Rosuvastatin and Cyclosporine A in Chimeric Mice with Humanized Liver
Uchida, Masashi, Tajima, Yoriko, Kakuni, Masakazu, Kageyama, Yutaka, Okada, Taro, Sakurada, Eri, Tateno, Chise, Hayashi, Ryoji
Published in Drug metabolism and disposition (01.01.2018)
Published in Drug metabolism and disposition (01.01.2018)
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Predictability of human pharmacokinetics of drugs that undergo hepatic organic anion transporting polypeptide (OATP)-mediated transport using single-species allometric scaling in chimeric mice with humanized liver: integration with hepatic drug metabolism
Sanoh, Seigo, Naritomi, Yoichi, Kitamura, Satoshi, Shinagawa, Akihiko, Kakuni, Masakazu, Tateno, Chise, Ohta, Shigeru
Published in Xenobiotica (01.11.2020)
Published in Xenobiotica (01.11.2020)
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Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection
Yamamoto, Naoki, Sato, Yusuke, Munakata, Tsubasa, Kakuni, Masakazu, Tateno, Chise, Sanada, Takahiro, Hirata, Yuichi, Murakami, Shuko, Tanaka, Yasuhito, Chayama, Kazuaki, Hatakeyama, Hiroto, Hyodo, Mamoru, Harashima, Hideyoshi, Kohara, Michinori
Published in Journal of hepatology (01.03.2016)
Published in Journal of hepatology (01.03.2016)
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Chimeric Mice With Humanized Livers Demonstrate Human-Specific Hepatotoxicity Caused by a Therapeutic Antibody Against TRAIL-Receptor 2/Death Receptor 5
Nihira, Kaito, Nan-ya, Ken-ichiro, Kakuni, Masakazu, Ono, Yoko, Yoshikawa, Yukitaka, Ota, Toshio, Hiura, Masanori, Yoshinari, Kouichi
Published in Toxicological sciences (01.01.2019)
Published in Toxicological sciences (01.01.2019)
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