Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS -Mutant Cancer Cells
Erber, Johanna, Steiner, Joachim D, Isensee, Jörg, Lobbes, Leonard A, Toschka, André, Beleggia, Filippo, Schmitt, Anna, Kaiser, Rainer W J, Siedek, Florian, Persigehl, Thorsten, Hucho, Tim, Reinhardt, Hans C
Published in Cancer research (Chicago, Ill.) (01.10.2019)
Published in Cancer research (Chicago, Ill.) (01.10.2019)
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Journal Article
Development of amoebic liver abscess in early pregnancy years after initial amoebic exposure: a case report
Kaiser, Rainer W J, Allgeier, Julian, Philipp, Alexander B, Mayerle, Julia, Rothe, Camilla, Wallrauch, Claudia, Op den Winkel, Mark
Published in BMC gastroenterology (14.12.2020)
Published in BMC gastroenterology (14.12.2020)
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Journal Article
Neutrophil-Platelet Interactions as Novel Treatment Targets in Cardiovascular Disease
Kaiser, Rainer, Escaig, Raphael, Erber, Johanna, Nicolai, Leo
Published in Frontiers in cardiovascular medicine (31.01.2022)
Published in Frontiers in cardiovascular medicine (31.01.2022)
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Journal Article
A protein-RNA interaction atlas of the ribosome biogenesis factor AATF
Kaiser, Rainer W. J., Ignarski, Michael, Van Nostrand, Eric L., Frese, Christian K., Jain, Manaswita, Cukoski, Sadrija, Heinen, Heide, Schaechter, Melanie, Seufert, Lisa, Bunte, Konstantin, Frommolt, Peter, Keller, Patrick, Helm, Mark, Bohl, Katrin, Höhne, Martin, Schermer, Bernhard, Benzing, Thomas, Höpker, Katja, Dieterich, Christoph, Yeo, Gene W., Müller, Roman-Ulrich, Fabretti, Francesca
Published in Scientific reports (30.07.2019)
Published in Scientific reports (30.07.2019)
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Journal Article
Inactivation of Apoptosis Antagonizing Transcription Factor in tubular epithelial cells induces accumulation of DNA damage and nephronophthisis
Jain, Manaswita, Kaiser, Rainer W.J., Bohl, Katrin, Hoehne, Martin, Göbel, Heike, Bartram, Malte P., Habbig, Sandra, Müller, Roman-Ulrich, Fogo, Agnes B., Benzing, Thomas, Schermer, Bernhard, Höpker, Katja, Slaats, Gisela G.
Published in Kidney international (01.04.2019)
Published in Kidney international (01.04.2019)
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Journal Article
The RNA-Protein Interactome of Differentiated Kidney Tubular Epithelial Cells
Ignarski, Michael, Rill, Constantin, Kaiser, Rainer W J, Kaldirim, Madlen, Neuhaus, René, Esmaillie, Reza, Li, Xinping, Klein, Corinna, Bohl, Katrin, Petersen, Maike, Frese, Christian K, Höhne, Martin, Atanassov, Ilian, Rinschen, Markus M, Höpker, Katja, Schermer, Bernhard, Benzing, Thomas, Dieterich, Christoph, Fabretti, Francesca, Müller, Roman-Ulrich
Published in Journal of the American Society of Nephrology (01.04.2019)
Published in Journal of the American Society of Nephrology (01.04.2019)
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Journal Article
Single platelet and megakaryocyte morpho-dynamics uncovered by multicolor reporter mouse strains in vitro and in vivo
Nicolai, Leo, Kaiser, Rainer, Escaig, Raphael, Hoffknecht, Marie-Louise, Anjum, Afra, Leunig, Alexander, Pircher, Joachim, Ehrlich, Andreas, Lorenz, Michael, Ishikawa-Ankerhold, Hellen, Aird, William C., Massberg, Steffen, Gaertner, Florian
Published in Haematologica (Roma) (01.07.2022)
Published in Haematologica (Roma) (01.07.2022)
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Journal Article
Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection
Pekayvaz, Kami, Leunig, Alexander, Kaiser, Rainer, Joppich, Markus, Brambs, Sophia, Janjic, Aleksandar, Popp, Oliver, Nixdorf, Daniel, Fumagalli, Valeria, Schmidt, Nora, Polewka, Vivien, Anjum, Afra, Knottenberg, Viktoria, Eivers, Luke, Wange, Lucas E., Gold, Christoph, Kirchner, Marieluise, Muenchhoff, Maximilian, Hellmuth, Johannes C., Scherer, Clemens, Rubio-Acero, Raquel, Eser, Tabea, Deák, Flora, Puchinger, Kerstin, Kuhl, Niklas, Linder, Andreas, Saar, Kathrin, Tomas, Lukas, Schulz, Christian, Wieser, Andreas, Enard, Wolfgang, Kroidl, Inge, Geldmacher, Christof, von Bergwelt-Baildon, Michael, Keppler, Oliver T., Munschauer, Mathias, Iannacone, Matteo, Zimmer, Ralf, Mertins, Philipp, Hubner, Norbert, Hoelscher, Michael, Massberg, Steffen, Stark, Konstantin, Nicolai, Leo
Published in Nature communications (23.02.2022)
Published in Nature communications (23.02.2022)
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Journal Article
Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19
Kaiser, Rainer, Leunig, Alexander, Pekayvaz, Kami, Popp, Oliver, Joppich, Markus, Polewka, Vivien, Escaig, Raphael, Anjum, Afra, Hoffknecht, Marie-Louise, Gold, Christoph, Brambs, Sophia, Engel, Anouk, Stockhausen, Sven, Knottenberg, Viktoria, Titova, Anna, Haji, Mohamed, Scherer, Clemens, Muenchhoff, Maximilian, Hellmuth, Johannes C, Saar, Kathrin, Schubert, Benjamin, Hilgendorff, Anne, Schulz, Christian, Kääb, Stefan, Zimmer, Ralf, Hübner, Norbert, Massberg, Steffen, Mertins, Philipp, Nicolai, Leo, Stark, Konstantin
Published in JCI insight (22.09.2021)
Published in JCI insight (22.09.2021)
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Journal Article
Thromboinflammation in long COVID—the elusive key to postinfection sequelae?
Nicolai, Leo, Kaiser, Rainer, Stark, Konstantin
Published in Journal of thrombosis and haemostasis (01.08.2023)
Published in Journal of thrombosis and haemostasis (01.08.2023)
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Journal Article
Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy
Nicolai, Leo, Leunig, Alexander, Brambs, Sophia, Kaiser, Rainer, Weinberger, Tobias, Weigand, Michael, Muenchhoff, Maximilian, Hellmuth, Johannes C., Ledderose, Stephan, Schulz, Heiko, Scherer, Clemens, Rudelius, Martina, Zoller, Michael, Höchter, Dominik, Keppler, Oliver, Teupser, Daniel, Zwißler, Bernhard, von Bergwelt-Baildon, Michael, Kääb, Stefan, Massberg, Steffen, Pekayvaz, Kami, Stark, Konstantin
Published in Circulation (New York, N.Y.) (22.09.2020)
Published in Circulation (New York, N.Y.) (22.09.2020)
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Journal Article
Mechanosensing Via a Gp2b3a-Src-Axis Regulates Platelet Migration in Vitro and In Vivo
Nicolai, Leo, Kaiser, Rainer, Loew, Quentin, Kammerer, Lisa, Spiekermann, Karsten, Massberg, Steffen
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Thrombocytopenia and splenic platelet-directed immune responses after IV ChAdOx1 nCov-19 administration
Nicolai, Leo, Leunig, Alexander, Pekayvaz, Kami, Esefeld, Max, Anjum, Afra, Rath, Justina, Riedlinger, Eva, Ehreiser, Vincent, Mader, Magdalena, Eivers, Luke, Hoffknecht, Marie-Louise, Zhang, Zhe, Kugelmann, Daniela, Rossaro, Dario, Escaig, Raphael, Kaiser, Rainer, Polewka, Vivien, Titova, Anna, Petzold, Tobias, Spiekermann, Karsten, Iannacone, Matteo, Thiele, Thomas, Greinacher, Andreas, Stark, Konstantin, Massberg, Steffen
Published in Blood (04.08.2022)
Published in Blood (04.08.2022)
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Journal Article
Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID‐19 from influenza pneumonia
Nicolai, Leo, Leunig, Alexander, Brambs, Sophia, Kaiser, Rainer, Joppich, Markus, Hoffknecht, Marie‐Louise, Gold, Christoph, Engel, Anouk, Polewka, Vivien, Muenchhoff, Maximilian, Hellmuth, Johannes C., Ruhle, Adrian, Ledderose, Stephan, Weinberger, Tobias, Schulz, Heiko, Scherer, Clemens, Rudelius, Martina, Zoller, Michael, Keppler, Oliver T., Zwißler, Bernhard, Bergwelt‐Baildon, Michael, Kääb, Stefan, Zimmer, Ralf, Bülow, Roman D., Stillfried, Saskia, Boor, Peter, Massberg, Steffen, Pekayvaz, Kami, Stark, Konstantin
Published in Journal of thrombosis and haemostasis (01.02.2021)
Published in Journal of thrombosis and haemostasis (01.02.2021)
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Journal Article
Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI
Kaiser, Rainer, Escaig, Raphael, Kranich, Jan, Hoffknecht, Marie-Louise, Anjum, Afra, Polewka, Vivien, Mader, Magdalena, Hu, Wenbo, Belz, Larissa, Gold, Christoph, Titova, Anna, Lorenz, Michael, Pekayvaz, Kami, Kääb, Stefan, Gaertner, Florian, Stark, Konstantin, Brocker, Thomas, Massberg, Steffen, Nicolai, Leo
Published in Blood (14.07.2022)
Published in Blood (14.07.2022)
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Journal Article
Immunothrombotic Signatures of Resident and Circulating Immune Cells in Human Infective Endocarditis Revealed By Multi-Omic Profiling
Kaiser, Rainer, Joppich, Markus, Droste, Augustin, Knottenberg, Viktoria, Akhalkatsi, Anastassia, Saha, Shekhar, Hagl, Christian, Escaig, Raphael, Massberg, Steffen, Draenert, Rika, Stark, Konstantin, Nicolai, Leo, Pekayvaz, Kami
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Mechanosensing via a GpIIb/Src/14-3-3ζ axis critically regulates platelet migration in vascular inflammation
Kaiser, Rainer, Anjum, Afra, Kammerer, Lisa, Loew, Quentin, Akhalkatsi, Anastassia, Rossaro, Dario, Escaig, Raphael, Droste zu Senden, Augustin, Raude, Ben, Lorenz, Michael, Gold, Christoph, Pekayvaz, Kami, Brocker, Thomas, Kranich, Jan, Holch, Julian Walter, Spiekermann, Karsten, Massberg, Steffen, Gaertner, Florian, Nicolai, Leo
Published in Blood (15.06.2023)
Published in Blood (15.06.2023)
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Journal Article