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Published in Cell (06.08.2020)
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T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
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Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
Hara, Toshiro, Chanoch-Myers, Rony, Mathewson, Nathan D., Myskiw, Chad, Atta, Lyla, Bussema, Lillian, Eichhorn, Stephen W., Greenwald, Alissa C., Kinker, Gabriela S., Rodman, Christopher, Gonzalez Castro, L. Nicolas, Wakimoto, Hiroaki, Rozenblatt-Rosen, Orit, Zhuang, Xiaowei, Fan, Jean, Hunter, Tony, Verma, Inder M., Wucherpfennig, Kai W., Regev, Aviv, Suvà, Mario L., Tirosh, Itay
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Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
Filbin, Mariella G, Tirosh, Itay, Hovestadt, Volker, Shaw, McKenzie L, Escalante, Leah E, Mathewson, Nathan D, Neftel, Cyril, Frank, Nelli, Pelton, Kristine, Hebert, Christine M, Haberler, Christine, Yizhak, Keren, Gojo, Johannes, Egervari, Kristof, Mount, Christopher, van Galen, Peter, Bonal, Dennis M, Nguyen, Quang-De, Beck, Alexander, Sinai, Claire, Czech, Thomas, Dorfer, Christian, Goumnerova, Liliana, Lavarino, Cinzia, Carcaboso, Angel M, Mora, Jaume, Mylvaganam, Ravindra, Luo, Christina C, Peyrl, Andreas, Popović, Mara, Azizi, Amedeo, Batchelor, Tracy T, Frosch, Matthew P, Martinez-Lage, Maria, Kieran, Mark W, Bandopadhayay, Pratiti, Beroukhim, Rameen, Fritsch, Gerhard, Getz, Gad, Rozenblatt-Rosen, Orit, Wucherpfennig, Kai W, Louis, David N, Monje, Michelle, Slavc, Irene, Ligon, Keith L, Golub, Todd R, Regev, Aviv, Bernstein, Bradley E, Suvà, Mario L
Published in Science (American Association for the Advancement of Science) (20.04.2018)
Published in Science (American Association for the Advancement of Science) (20.04.2018)
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Deconstructing the Peptide-MHC Specificity of T Cell Recognition
Birnbaum, Michael E., Mendoza, Juan L., Sethi, Dhruv K., Dong, Shen, Glanville, Jacob, Dobbins, Jessica, Özkan, Engin, Davis, Mark M., Wucherpfennig, Kai W., Garcia, K. Christopher
Published in Cell (22.05.2014)
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Systematic investigation of cytokine signaling activity at the tissue and single-cell levels
Jiang, Peng, Zhang, Yu, Ru, Beibei, Yang, Yuan, Vu, Trang, Paul, Rohit, Mirza, Amer, Altan-Bonnet, Grégoire, Liu, Lingrui, Ruppin, Eytan, Wakefield, Lalage, Wucherpfennig, Kai W.
Published in Nature methods (01.10.2021)
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Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity
Ferrari de Andrade, Lucas, Tay, Rong En, Pan, Deng, Luoma, Adrienne M, Ito, Yoshinaga, Badrinath, Soumya, Tsoucas, Daphne, Franz, Bettina, May, Jr, Kenneth F, Harvey, Christopher J, Kobold, Sebastian, Pyrdol, Jason W, Yoon, Charles, Yuan, Guo-Cheng, Hodi, F Stephen, Dranoff, Glenn, Wucherpfennig, Kai W
Published in Science (American Association for the Advancement of Science) (30.03.2018)
Published in Science (American Association for the Advancement of Science) (30.03.2018)
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Landscape of B cell immunity and related immune evasion in human cancers
Hu, Xihao, Zhang, Jian, Wang, Jin, Fu, Jingxin, Li, Taiwen, Zheng, Xiaoqi, Wang, Binbin, Gu, Shengqing, Jiang, Peng, Fan, Jingyu, Ying, Xiaomin, Zhang, Jing, Carroll, Michael C., Wucherpfennig, Kai W., Hacohen, Nir, Zhang, Fan, Zhang, Peng, Liu, Jun S., Li, Bo, Liu, X. Shirley
Published in Nature genetics (01.03.2019)
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Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Jerby-Arnon, Livnat, Neftel, Cyril, Shore, Marni E., Weisman, Hannah R., Mathewson, Nathan D., McBride, Matthew J., Haas, Brian, Izar, Benjamin, Volorio, Angela, Boulay, Gaylor, Cironi, Luisa, Richman, Alyssa R., Broye, Liliane C., Gurski, Joseph M., Luo, Christina C., Mylvaganam, Ravindra, Nguyen, Lan, Mei, Shaolin, Melms, Johannes C., Georgescu, Christophe, Cohen, Ofir, Buendia-Buendia, Jorge E., Segerstolpe, Asa, Sud, Malika, Cuoco, Michael S., Labes, Danny, Gritsch, Simon, Zollinger, Daniel R., Ortogero, Nicole, Beechem, Joseph M., Petur Nielsen, G., Chebib, Ivan, Nguyen-Ngoc, Tu, Montemurro, Michael, Cote, Gregory M., Choy, Edwin, Letovanec, Igor, Cherix, Stéphane, Wagle, Nikhil, Sorger, Peter K., Haynes, Alex B., Mullen, John T., Stamenkovic, Ivan, Rivera, Miguel N., Kadoch, Cigall, Wucherpfennig, Kai W., Rozenblatt-Rosen, Orit, Suvà, Mario L., Riggi, Nicolò, Regev, Aviv
Published in Nature medicine (01.02.2021)
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MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets
Qiu, Xintao, Boufaied, Nadia, Hallal, Tarek, Feit, Avery, de Polo, Anna, Luoma, Adrienne M., Alahmadi, Walaa, Larocque, Janie, Zadra, Giorgia, Xie, Yingtian, Gu, Shengqing, Tang, Qin, Zhang, Yi, Syamala, Sudeepa, Seo, Ji-Heui, Bell, Connor, O’Connor, Edward, Liu, Yang, Schaeffer, Edward M., Jeffrey Karnes, R., Weinmann, Sheila, Davicioni, Elai, Morrissey, Colm, Cejas, Paloma, Ellis, Leigh, Loda, Massimo, Wucherpfennig, Kai W., Pomerantz, Mark M., Spratt, Daniel E., Corey, Eva, Freedman, Matthew L., Shirley Liu, X., Brown, Myles, Long, Henry W., Labbé, David P.
Published in Nature communications (13.05.2022)
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FAP Delineates Heterogeneous and Functionally Divergent Stromal Cells in Immune-Excluded Breast Tumors
Cremasco, Viviana, Astarita, Jillian L, Grauel, Angelo L, Keerthivasan, Shilpa, MacIsaac, Kenzie, Woodruff, Matthew C, Wu, Michael, Spel, Lotte, Santoro, Stephen, Amoozgar, Zohreh, Laszewski, Tyler, Migoni, Sara Cruz, Knoblich, Konstantin, Fletcher, Anne L, LaFleur, Martin, Wucherpfennig, Kai W, Pure, Ellen, Dranoff, Glenn, Carroll, Michael C, Turley, Shannon J
Published in Cancer immunology research (01.12.2018)
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Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer
Ge, Jennifer Y., Shu, Shaokun, Kwon, Mijung, Jovanović, Bojana, Murphy, Katherine, Gulvady, Anushree, Fassl, Anne, Trinh, Anne, Kuang, Yanan, Heavey, Grace A., Luoma, Adrienne, Paweletz, Cloud, Thorner, Aaron R., Wucherpfennig, Kai W., Qi, Jun, Brown, Myles, Sicinski, Piotr, McDonald, Thomas O., Pellman, David, Michor, Franziska, Polyak, Kornelia
Published in Nature communications (11.05.2020)
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Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2
Acton, Sophie E., Astarita, Jillian L., Malhotra, Deepali, Lukacs-Kornek, Veronika, Franz, Bettina, Hess, Paul R., Jakus, Zoltan, Kuligowski, Michael, Fletcher, Anne L., Elpek, Kutlu G., Bellemare-Pelletier, Angelique, Sceats, Lindsay, Reynoso, Erika D., Gonzalez, Santiago F., Graham, Daniel B., Chang, Jonathan, Peters, Anneli, Woodruff, Matthew, Kim, Young-A., Swat, Wojciech, Morita, Takashi, Kuchroo, Vijay, Carroll, Michael C., Kahn, Mark L., Wucherpfennig, Kai W., Turley, Shannon J.
Published in Immunity (Cambridge, Mass.) (24.08.2012)
Published in Immunity (Cambridge, Mass.) (24.08.2012)
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Multicomponent Injectable Hydrogels for Antigen-Specific Tolerogenic Immune Modulation
Verbeke, Catia S, Gordo, Susana, Schubert, David A, Lewin, Sarah A, Desai, Rajiv M, Dobbins, Jessica, Wucherpfennig, Kai W, Mooney, David J
Published in Advanced healthcare materials (01.03.2017)
Published in Advanced healthcare materials (01.03.2017)
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Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals
Kardava, Lela, Moir, Susan, Shah, Naisha, Wang, Wei, Wilson, Richard, Buckner, Clarisa M, Santich, Brian H, Kim, Leo J Y, Spurlin, Emily E, Nelson, Amy K, Wheatley, Adam K, Harvey, Christopher J, McDermott, Adrian B, Wucherpfennig, Kai W, Chun, Tae-Wook, Tsang, John S, Li, Yuxing, Fauci, Anthony S
Published in The Journal of clinical investigation (01.07.2014)
Published in The Journal of clinical investigation (01.07.2014)
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Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses
Clark, Lars E., Mahmutovic, Selma, Raymond, Donald D., Dilanyan, Taleen, Koma, Takaaki, Manning, John T., Shankar, Sundaresh, Levis, Silvana C., Briggiler, Ana M., Enria, Delia A., Wucherpfennig, Kai W., Paessler, Slobodan, Abraham, Jonathan
Published in Nature communications (14.05.2018)
Published in Nature communications (14.05.2018)
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Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling
Dobbins, Jessica, Gagnon, Etienne, Godec, Jernej, Pyrdol, Jason, Vignali, Dario A A, Sharpe, Arlene H, Wucherpfennig, Kai W
Published in Science signaling (26.07.2016)
Published in Science signaling (26.07.2016)
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Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity
Melms, Johannes C, Vallabhaneni, Sreeram, Mills, Caitlin E, Yapp, Clarence, Chen, Jia-Yun, Morelli, Eugenio, Waszyk, Patricia, Kumar, Sushil, Deming, Derrick, Moret, Nienke, Rodriguez, Steven, Subramanian, Kartik, Rogava, Meri, Cartwright, Adam N R, Luoma, Adrienne, Mei, Shaolin, Brinker, Titus J, Miller, David M, Spektor, Alexander, Schadendorf, Dirk, Riggi, Nicolo, Wucherpfennig, Kai W, Sorger, Peter K, Izar, Benjamin
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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