Roles and regulations of the ETS transcription factor ELF4/MEF
Suico, Mary Ann, Shuto, Tsuyoshi, Kai, Hirofumi
Published in Journal of molecular cell biology (01.06.2017)
Published in Journal of molecular cell biology (01.06.2017)
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Development of an exon skipping therapy for X-linked Alport syndrome with truncating variants in COL4A5
Yamamura, Tomohiko, Horinouchi, Tomoko, Adachi, Tomomi, Terakawa, Maki, Takaoka, Yutaka, Omachi, Kohei, Takasato, Minoru, Takaishi, Kiyosumi, Shoji, Takao, Onishi, Yoshiyuki, Kanazawa, Yoshito, Koizumi, Makoto, Tomono, Yasuko, Sugano, Aki, Shono, Akemi, Minamikawa, Shogo, Nagano, China, Sakakibara, Nana, Ishiko, Shinya, Aoto, Yuya, Kamura, Misato, Harita, Yutaka, Miura, Kenichiro, Kanda, Shoichiro, Morisada, Naoya, Rossanti, Rini, Ye, Ming Juan, Nozu, Yoshimi, Matsuo, Masafumi, Kai, Hirofumi, Iijima, Kazumoto, Nozu, Kandai
Published in Nature communications (02.06.2020)
Published in Nature communications (02.06.2020)
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Metformin ameliorates the severity of experimental Alport syndrome
Omachi, Kohei, Kaseda, Shota, Yokota, Tsubasa, Kamura, Misato, Teramoto, Keisuke, Kuwazuru, Jun, Kojima, Haruka, Nohara, Hirofumi, Koyama, Kosuke, Ohtsuki, Sumio, Misumi, Shogo, Takeo, Toru, Nakagata, Naomi, Li, Jian-Dong, Shuto, Tsuyoshi, Suico, Mary Ann, Miner, Jeffrey H., Kai, Hirofumi
Published in Scientific reports (29.03.2021)
Published in Scientific reports (29.03.2021)
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Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M
Miyata, Masanori, Lee, Ji-Yun, Susuki-Miyata, Seiko, Wang, Wenzhuo Y., Xu, Haidong, Kai, Hirofumi, Kobayashi, Koichi S., Flavell, Richard A., Li, Jian-Dong
Published in Nature communications (14.01.2015)
Published in Nature communications (14.01.2015)
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Journal Article
Azithromycin Inhibits Constitutive Airway Epithelial Sodium Channel Activation in Vitro and Modulates Downstream Pathogenesis in Vivo
Fujikawa, Haruka, Kawakami, Taise, Nakashima, Ryunosuke, Nasu, Aoi, Kamei, Shunsuke, Nohara, Hirofumi, Eto, Yuka, Ueno-Shuto, Keiko, Takeo, Toru, Nakagata, Naomi, Suico, Mary Ann, Kai, Hirofumi, Shuto, Tsuyoshi
Published in Biological & pharmaceutical bulletin (01.04.2020)
Published in Biological & pharmaceutical bulletin (01.04.2020)
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Journal Article
Curcumin Down-Regulates Toll-Like Receptor-2 Gene Expression and Function in Human Cystic Fibrosis Bronchial Epithelial Cells
Chaudhary, Niraj, Ueno-Shuto, Keiko, Ono, Tomomi, Ohira, Yuko, Watanabe, Kenji, Nasu, Aoi, Fujikawa, Haruka, Nakashima, Ryunosuke, Takahashi, Noriki, Suico, Mary Ann, Kai, Hirofumi, Shuto, Tsuyoshi
Published in Biological & pharmaceutical bulletin (01.03.2019)
Published in Biological & pharmaceutical bulletin (01.03.2019)
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Journal Article
Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors
Sasaki, Ryoko, Suico, Mary Ann, Chosa, Keisuke, Teranishi, Yuriko, Sato, Takashi, Kagami, Asuka, Kotani, Shunsuke, Kato, Hikaru, Hitora, Yuki, Tsukamoto, Sachiko, Yamashita, Tomohiro, Yokoyama, Takeshi, Mizuguchi, Mineyuki, Kai, Hirofumi, Shuto, Tsuyoshi
Published in Journal of pharmacological sciences (01.01.2023)
Published in Journal of pharmacological sciences (01.01.2023)
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Journal Article
The 2019 and 2021 International Workshops on Alport Syndrome
Daga, Sergio, Ding, Jie, Deltas, Constantinos, Savige, Judy, Lipska-Ziętkiewicz, Beata S, Hoefele, Julia, Flinter, Frances, Gale, Daniel P, Aksenova, Marina, Kai, Hirofumi, Perin, Laura, Barua, Moumita, Torra, Roser, Miner, Jeff H, Massella, Laura, Ljubanović, Danica Galešić, Lennon, Rachel, Weinstock, Andrè B, Knebelmann, Bertrand, Cerkauskaite, Agne, Gear, Susie, Gross, Oliver, Turner, A Neil, Baldassarri, Margherita, Pinto, Anna Maria, Renieri, Alessandra
Published in European journal of human genetics : EJHG (01.05.2022)
Published in European journal of human genetics : EJHG (01.05.2022)
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Journal Article
A Splice Switch in SIGIRR Causes a Defect of IL-37-Dependent Anti-Inflammatory Activity in Cystic Fibrosis Airway Epithelial Cells
Ueno-Shuto, Keiko, Kamei, Shunsuke, Hayashi, Megumi, Fukuyama, Ayami, Uchida, Yuji, Tokutomi, Naofumi, Suico, Mary Ann, Kai, Hirofumi, Shuto, Tsuyoshi
Published in International journal of molecular sciences (13.07.2022)
Published in International journal of molecular sciences (13.07.2022)
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Journal Article
Hydrogen bonds connecting the N-terminal region and the DE loop stabilize the monomeric structure of transthyretin
Inada, Yuki, Ono, Yuichiro, Okazaki, Kyo, Yamashita, Takuma, Kawaguchi, Tomoyuki, Kawano, Shingo, Kobashigawa, Yoshihiro, Shinya, Shoko, Kojima, Chojiro, Shuto, Tsuyoshi, Kai, Hirofumi, Morioka, Hiroshi, Sato, Takashi
Published in Journal of biochemistry (Tokyo) (29.09.2023)
Published in Journal of biochemistry (Tokyo) (29.09.2023)
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Journal Article
Metformin suppresses epithelial sodium channel hyperactivation and its associated phenotypes in a mouse model of obstructive lung diseases
Nakashima, Ryunosuke, Nohara, Hirofumi, Takahashi, Noriki, Nasu, Aoi, Hayashi, Megumi, Kishimoto, Tomoki, Kamei, Shunsuke, Fujikawa, Haruka, Maruta, Kasumi, Kawakami, Taisei, Eto, Yuka, Ueno-Shuto, Keiko, Suico, Mary Ann, Kai, Hirofumi, Shuto, Tsuyoshi
Published in Journal of pharmacological sciences (01.06.2022)
Published in Journal of pharmacological sciences (01.06.2022)
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Journal Article
Intrapopulation analysis of longitudinal lifespan in Caenorhabditis elegans identifies W09D10.4 as a novel AMPK-associated healthspan shortening factor
Nakano, Yoshio, Moriuchi, Masataka, Fukushima, Yutaro, Hayashi, Kyotaro, Suico, Mary Ann, Kai, Hirofumi, Koutaki, Go, Shuto, Tsuyoshi
Published in Journal of pharmacological sciences (01.03.2021)
Published in Journal of pharmacological sciences (01.03.2021)
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Nitric oxide facilitates the targeting Kupffer cells of a nano-antioxidant for the treatment of NASH
Maeda, Hitoshi, Ishima, Yu, Saruwatari, Junji, Mizuta, Yuki, Minayoshi, Yuki, Ichimizu, Shota, Yanagisawa, Hiroki, Nagasaki, Taisei, Yasuda, Kengo, Oshiro, Shun, Taura, Manabu, McConnell, Matthew J., Oniki, Kentaro, Sonoda, Kayoko, Wakayama, Tomohiko, Kinoshita, Manabu, Shuto, Tsuyoshi, Kai, Hirofumi, Tanaka, Motohiko, Sasaki, Yutaka, Iwakiri, Yasuko, Otagiri, Masaki, Watanabe, Hiroshi, Maruyama, Toru
Published in Journal of controlled release (01.01.2022)
Published in Journal of controlled release (01.01.2022)
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Combined effects of cisplatin and photon or proton irradiation in cultured cells: radiosensitization, patterns of cell death and cell cycle distribution
Iwata, Hiromitsu, Shuto, Tsuyoshi, Kamei, Shunsuke, Omachi, Kohei, Moriuchi, Masataka, Omachi, Chihiro, Toshito, Toshiyuki, Hashimoto, Shingo, Nakajima, Koichiro, Sugie, Chikao, Ogino, Hiroyuki, Kai, Hirofumi, Shibamoto, Yuta
Published in Journal of radiation research (01.11.2020)
Published in Journal of radiation research (01.11.2020)
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Journal Article
A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome
Omachi, Kohei, Kamura, Misato, Teramoto, Keisuke, Kojima, Haruka, Yokota, Tsubasa, Kaseda, Shota, Kuwazuru, Jun, Fukuda, Ryosuke, Koyama, Kosuke, Matsuyama, Shingo, Motomura, Keishi, Shuto, Tsuyoshi, Suico, Mary Ann, Kai, Hirofumi
Published in Cell chemical biology (17.05.2018)
Published in Cell chemical biology (17.05.2018)
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Journal Article
Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions
Oniki, Kentaro, Kawakami, Taisei, Nakashima, Azusa, Miyata, Keishi, Watanabe, Takehisa, Fujikawa, Haruka, Nakashima, Ryunosuke, Nasu, Aoi, Eto, Yuka, Takahashi, Noriki, Nohara, Hirofumi, Suico, Mary Ann, Kotani, Shunsuke, Obata, Yui, Sakamoto, Yuki, Seguchi, Yuri, Saruwatari, Junji, Imafuku, Tadashi, Watanabe, Hiroshi, Maruyama, Toru, Kai, Hirofumi, Shuto, Tsuyoshi
Published in Scientific reports (09.03.2020)
Published in Scientific reports (09.03.2020)
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Journal Article
TLR3 induction by anticancer drugs potentiates poly I:C‐induced tumor cell apoptosis
Taura, Manabu, Fukuda, Ryosuke, Suico, Mary Ann, Eguma, Ayaka, Koga, Tomoaki, Shuto, Tsuyoshi, Sato, Takashi, Morino‐Koga, Saori, Kai, Hirofumi
Published in Cancer science (01.07.2010)
Published in Cancer science (01.07.2010)
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Journal Article
STAT3 inhibition attenuates the progressive phenotypes of Alport syndrome mouse model
Yokota, Tsubasa, Omachi, Kohei, Suico, Mary Ann, Kamura, Misato, Kojima, Haruka, Fukuda, Ryosuke, Motomura, Keishi, Teramoto, Keisuke, Kaseda, Shota, Kuwazuru, Jun, Takeo, Toru, Nakagata, Naomi, Shuto, Tsuyoshi, Kai, Hirofumi
Published in Nephrology, dialysis, transplantation (01.02.2018)
Published in Nephrology, dialysis, transplantation (01.02.2018)
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Journal Article
Characterization of Non-amyloidogenic G101S Transthyretin
Wakita, Yuriko, Sato, Takashi, Chosa, Keisuke, Suico, Mary Ann, Sasaki, Ryoko, Kawano, Shingo, Hashimoto, Nami, Teranishi, Yuriko, Imai, Yoshiki, Morioka, Hiroshi, Shuto, Tsuyoshi, Kai, Hirofumi
Published in Biological & pharmaceutical bulletin (2018)
Published in Biological & pharmaceutical bulletin (2018)
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Journal Article
Cross-talk between PKA-Cβ and p65 mediates synergistic induction of PDE4B by roflumilast and NTHi
Susuki-Miyata, Seiko, Miyata, Masanori, Lee, Byung-Cheol, Xu, Haidong, Kai, Hirofumi, Yan, Chen, Li, Jian-Dong
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2015)
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