Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses
Kahraman, Sevim, Shibue, Kimitaka, De Jesus, Dario F, Kim, Hyunki, Hu, Jiang, Manna, Debasish, Wagner, Bridget, Choudhary, Amit, Kulkarni, Rohit N
Published in eLife (21.09.2023)
Published in eLife (21.09.2023)
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Journal Article
Expiratory Muscle Strength Training Reduces Oxidative Stress and Systemic Inflammation in Men with Obstructive Sleep Apnea Syndrome: A Double-Blinded, Randomized Parallel Trial
Erturk, Nurel, Celik, Adem, Kahraman Yaman, Sevim, Yaman, Huseyin, Unal, Ferhat, Calik Kutukcu, Ebru
Published in Sleep (New York, N.Y.) (19.09.2024)
Published in Sleep (New York, N.Y.) (19.09.2024)
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Journal Article
Essential roles of insulin and IGF-1 receptors during embryonic lineage development
Okawa, Erin R., Gupta, Manoj K., Kahraman, Sevim, Goli, Praneeth, Sakaguchi, Masaji, Hu, Jiang, Duan, Kaiti, Slipp, Brittany, Lennerz, Jochen K., Kulkarni, Rohit N.
Published in Molecular metabolism (Germany) (01.05.2021)
Published in Molecular metabolism (Germany) (01.05.2021)
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Journal Article
Leptin Receptor Signaling Regulates Protein Synthesis Pathways and Neuronal Differentiation in Pluripotent Stem Cells
Gupta, Manoj K., Vethe, Heidrun, Softic, Samir, Rao, Tata Nageswara, Wagh, Vilas, Shirakawa, Jun, Barsnes, Harald, Vaudel, Marc, Takatani, Tomozumi, Kahraman, Sevim, Sakaguchi, Masaji, Martinez, Rachael, Hu, Jiang, Bjørlykke, Yngvild, Raeder, Helge, Kulkarni, Rohit N.
Published in Stem cell reports (10.11.2020)
Published in Stem cell reports (10.11.2020)
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Journal Article
Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation
Gupta, Manoj K., De Jesus, Dario F., Kahraman, Sevim, Valdez, Ivan A., Shamsi, Farnaz, Yi, Lian, Swensen, Adam C., Tseng, Yu-Hua, Qian, Wei-Jun, Kulkarni, Rohit N.
Published in Molecular metabolism (Germany) (01.12.2018)
Published in Molecular metabolism (Germany) (01.12.2018)
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Journal Article
Inhibition of DYRK1A Stimulates Human β-Cell Proliferation
Dirice, Ercument, Walpita, Deepika, Vetere, Amedeo, Meier, Bennett C, Kahraman, Sevim, Hu, Jiang, Dančík, Vlado, Burns, Sean M, Gilbert, Tamara J, Olson, David E, Clemons, Paul A, Kulkarni, Rohit N, Wagner, Bridget K
Published in Diabetes (New York, N.Y.) (01.06.2016)
Published in Diabetes (New York, N.Y.) (01.06.2016)
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Journal Article
83-OR: Pancreatic Exocrine to Endocrine Cell Cross Talk Mediates Endoplasmic Reticulum Stress and Beta-Cell Dysfunction in MODY8
KAHRAMAN, SEVIM, DIEGISSER, DANIELLE, JOHANSSON, BENTE B., MOLVEN, ANDERS, KULKARNI, ROHIT
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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Journal Article
m6A mRNA methylation by METTL14 regulates early pancreatic cell differentiation
Kahraman, Sevim, De Jesus, Dario F, Wei, Jiangbo, Brown, Natalie K, Zou, Zhongyu, Hu, Jiang, Pirouz, Mehdi, Gregory, Richard I, He, Chuan, Kulkarni, Rohit N
Published in The EMBO journal (25.09.2024)
Published in The EMBO journal (25.09.2024)
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Journal Article
1557-P: Increased PAHSA Hydrolysis Driven by Mutant Carboxyl Ester Lipase (CEL) Contributes to Beta-Cell Dysfunction in MODY8
SANTORO, ANNA, KAHRAMAN, SEVIM, BASILE, GIORGIO, EL JELLAS, KHADIJA, HU, JIANG, TARPEY, RYAN, JOHANSSON, BENTE B., DIRICE, ERCUMENT, SYED, ISMAIL, SIEGEL, DIONICIO, MOLVEN, ANDERS, KAHN, BARBARA B., KULKARNI, ROHIT
Published in Diabetes (New York, N.Y.) (14.06.2024)
Published in Diabetes (New York, N.Y.) (14.06.2024)
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Journal Article
83-OR: Defining the Transcriptome and Epitranscriptome of the ß-Cell Compensation to Insulin Resistance
DE JESUS, DARIO F., ZHANG, ZIJIE, WEI, JIANGBO, BROWN, NATALIE K., HU, JIANG, KAHRAMAN, SEVIM, DIRICE, ERCUMENT, KULKARNI, ROHIT
Published in Diabetes (New York, N.Y.) (20.06.2023)
Published in Diabetes (New York, N.Y.) (20.06.2023)
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Journal Article
SerpinB1 Promotes Pancreatic β Cell Proliferation
El Ouaamari, Abdelfattah, Dirice, Ercument, Gedeon, Nicholas, Hu, Jiang, Zhou, Jian-Ying, Shirakawa, Jun, Hou, Lifei, Goodman, Jessica, Karampelias, Christos, Qiang, Guifeng, Boucher, Jeremie, Martinez, Rachael, Gritsenko, Marina A., De Jesus, Dario F., Kahraman, Sevim, Bhatt, Shweta, Smith, Richard D., Beer, Hans-Dietmar, Jungtrakoon, Prapaporn, Gong, Yanping, Goldfine, Allison B., Liew, Chong Wee, Doria, Alessandro, Andersson, Olov, Qian, Wei-Jun, Remold-O’Donnell, Eileen, Kulkarni, Rohit N.
Published in Cell metabolism (12.01.2016)
Published in Cell metabolism (12.01.2016)
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Journal Article
Fluorescein-based sensors to purify human [alpha]-cells for functional and transcriptomic analyses
Kahraman, Sevim, Shibue, Kimitaka, De Jesus, Dario F, Kim, Hyunki, Hu, Jiang, Manna, Debasish, Wagner, Bridget, Choudhary, Amit, Kulkarni, Rohit N
Published in eLife (21.09.2023)
Published in eLife (21.09.2023)
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Journal Article
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes
De Jesus, Dario F., Zhang, Zijie, Brown, Natalie K., Li, Xiaolu, Xiao, Ling, Hu, Jiang, Gaffrey, Matthew J., Fogarty, Garrett, Kahraman, Sevim, Wei, Jiangbo, Basile, Giorgio, Rana, Tariq M., Mathews, Clayton, Powers, Alvin C., Parent, Audrey V., Atkinson, Mark A., Dhe-Paganon, Sirano, Eizirik, Decio L., Qian, Wei-Jun, He, Chuan, Kulkarni, Rohit N.
Published in Nature cell biology (01.03.2024)
Published in Nature cell biology (01.03.2024)
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Journal Article
Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring
Kahraman, Sevim, Dirice, Ercument, De Jesus, Dario F, Hu, Jiang, Kulkarni, Rohit N
Published in American journal of physiology: endocrinology and metabolism (15.11.2014)
Published in American journal of physiology: endocrinology and metabolism (15.11.2014)
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Journal Article
Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β‑Cells
Lee, Miseon, Maji, Basudeb, Manna, Debasish, Kahraman, Sevim, Elgamal, Ruth M, Small, Jonnell, Kokkonda, Praveen, Vetere, Amedeo, Goldberg, Jacob M, Lippard, Stephen J, Kulkarni, Rohit N, Wagner, Bridget K, Choudhary, Amit
Published in Journal of the American Chemical Society (08.04.2020)
Published in Journal of the American Chemical Society (08.04.2020)
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Journal Article
1811-P: Induction of Hepatic Steatosis by a Methionine Choline Deficient Diet Promotes FGF21-Induced Insulin Secretion Independent of Diabetes
KIMURA, TOMOHIKO, DE JESUS, DARIO F., FUKUDA, KAZUKI, KAHRAMAN, SEVIM, SHIBUE, KIMITAKA, ORIME, KAZUKI, KULKARNI, ROHIT
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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Journal Article