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Ho, Joseph D., Chau, Betty, Rodgers, Logan, Lu, Frances, Wilbur, Kelly L., Otto, Keith A., Chen, Yanyun, Song, Min, Riley, Jonathan P., Yang, Hsiu-Chiung, Reynolds, Nichole A., Kahl, Steven D., Lewis, Anjana Patel, Groshong, Christopher, Madsen, Russell E., Conners, Kris, Lineswala, Jayana P., Gheyi, Tarun, Saflor, Melbert-Brian Decipulo, Lee, Matthew R., Benach, Jordi, Baker, Kenton A., Montrose-Rafizadeh, Chahrzad, Genin, Michael J., Miller, Anne R., Hamdouchi, Chafiq
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Insulin exits skeletal muscle capillaries by fluid-phase transport
Williams, Ian M, Valenzuela, Francisco A, Kahl, Steven D, Ramkrishna, Doraiswami, Mezo, Adam R, Young, Jamey D, Wells, K Sam, Wasserman, David H
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LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders
Rorick-Kehn, Linda M., Witkin, Jeffrey M., Statnick, Michael A., Eberle, Elizabeth L., McKinzie, Jamie H., Kahl, Steven D., Forster, Beth M., Wong, Conrad J., Li, Xia, Crile, Robert S., Shaw, David B., Sahr, Allison E., Adams, Benjamin L., Quimby, Steven J., Diaz, Nuria, Jimenez, Alma, Pedregal, Concepcion, Mitch, Charles H., Knopp, Kelly L., Anderson, Wesley H., Cramer, Jeffrey W., McKinzie, David L.
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The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470)
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Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP)
Ho, Joseph D., Lee, Matthew R., Rauch, Charles T., Aznavour, Kristen, Park, Jonathan S., Luz, John G., Antonysamy, Stephen, Condon, Bradley, Maletic, Milan, Zhang, Aiping, Hickey, Michael J., Hughes, Norman E., Chandrasekhar, Srinivasan, Sloan, Ashley V., Gooding, Karen, Harvey, Anita, Yu, Xiao-Peng, Kahl, Steven D., Norman, Bryan H.
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Deficiency of a glycoprotein component of the dystrophin complex in dystrophic muscle
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Published in Nature (London) (24.05.1990)
Published in Nature (London) (24.05.1990)
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Combination of a Beta Adrenoceptor Modulator and a Norepinephrine-Serotonin Uptake Inhibitor for the Treatment of Obesity
Jesudason, Cynthia D., Baker, James E., Bryant, Robert D., Fisher, Jack W., O’Farrell, Libbey S., Gaich, Gregory A., He, Minxia M., Kahl, Steven D., Kriauciunas, Aidas V., Heiman, Mark L., Peters, Mary A., Rito, Christopher J., Satterwhite, Julie H., Tinsley, Frank C., Trankle, William G., Shuker, Anthony J.
Published in ACS medicinal chemistry letters (11.08.2011)
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Discovery of a Novel Series of Orally Active Nociceptin/Orphanin FQ (NOP) Receptor Antagonists Based on a Dihydrospiro(piperidine-4,7′-thieno[2,3‑c]pyran) Scaffold
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In Vivo and In Vitro Characterization of Basal Insulin Peglispro: A Novel Insulin Analog
Owens, Rebecca A, Hansen, Ryan J, Kahl, Steven D, Zhang, Chen, Ruan, Xiaoping, Koester, Anja, Li, Shun, Qian, Hui-Rong, Farmen, Mark W, Michael, M Dodson, Moyers, Julie S, Cutler, Jr, Gordon B, Vick, Andrew, Beals, John M
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Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery
Coussens, Nathan P., Sittampalam, G. Sitta, Guha, Rajarshi, Brimacombe, Kyle, Grossman, Abigail, Chung, Thomas D. Y., Weidner, Jeffrey R., Riss, Terry, Trask, O. Joseph, Auld, Douglas, Dahlin, Jayme L., Devanaryan, Viswanath, Foley, Timothy L., McGee, James, Kahl, Steven D., Kales, Stephen C., Arkin, Michelle, Baell, Jonathan, Bejcek, Bruce, Gal‐Edd, Neely, Glicksman, Marcie, Haas, Joseph V., Iversen, Philip W., Hoeppner, Marilu, Lathrop, Stacy, Sayers, Eric, Liu, Hanguan, Trawick, Bart, McVey, Julie, Lemmon, Vance P., Li, Zhuyin, McManus, Owen, Minor, Lisa, Napper, Andrew, Wildey, Mary Jo, Pacifici, Robert, Chin, William W., Xia, Menghang, Xu, Xin, Lal‐Nag, Madhu, Hall, Matthew D., Michael, Sam, Inglese, James, Simeonov, Anton, Austin, Christopher P.
Published in Clinical and translational science (01.09.2018)
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A selective GPR40 (FFAR1) agonist LY2881835 provides immediate and durable glucose control in rodent models of type 2 diabetes
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Published in Pharmacology research & perspectives (01.12.2016)
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pI-shifted insulin analogs with extended in vivo time action and favorable receptor selectivity
KOHN, Wayne D, MICANOUIC, Radmila, MAYER, John P, DIMARCHI, Richard D, MYERS, Sharon L, VICK, Andrew M, KAHL, Steuen D, LIANSHAN ZHANG, STRIFLER, Beth A, SHUN LI, JING SHANG, BEALS, John M
Published in Peptides (New York, N.Y. : 1980) (01.04.2007)
Published in Peptides (New York, N.Y. : 1980) (01.04.2007)
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Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle
Matsumura, Kiichiro, Ervasti, James M, Ohlendieck, Kay, Kahl, Steven D, Campbell, Kevin P
Published in Nature (London) (10.12.1992)
Published in Nature (London) (10.12.1992)
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Synthesis and Structure−Activity Relationships of Novel Arylpiperazines as Potent and Selective Agonists of the Melanocortin Subtype-4 Receptor
Richardson, Timothy I, Ornstein, Paul L, Briner, Karin, Fisher, Matthew J, Backer, Ryan T, Biggers, C. Kelly, Clay, Michael P, Emmerson, Paul J, Hertel, Larry W, Hsiung, Hansen M, Husain, Saba, Kahl, Steven D, Lee, Jonathan A, Lindstrom, Terry D, Martinelli, Michael J, Mayer, John P, Mullaney, Jeffery T, O'Brien, Thomas P, Pawlak, Joseph M, Revell, Kevin D, Shah, Jikesh, Zgombick, John M, Herr, R. Jason, Melekhov, Alex, Sampson, Peter B, King, Chi-Hsin R
Published in Journal of medicinal chemistry (29.01.2004)
Published in Journal of medicinal chemistry (29.01.2004)
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