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Published in Genes & development (01.05.2018)
Published in Genes & development (01.05.2018)
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Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury
Kenny, Elizabeth M, Fidan, Emin, Yang, Qin, Anthonymuthu, Tamil S, New, Lee Ann, Meyer, Elizabeth A, Wang, Hong, Kochanek, Patrick M, Dixon, C Edward, Kagan, Valerian E, Bayir, Hülya
Published in Critical care medicine (01.03.2019)
Published in Critical care medicine (01.03.2019)
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Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis
Bayır, Hülya, Anthonymuthu, Tamil S., Tyurina, Yulia Y., Patel, Sarju J., Amoscato, Andrew A., Lamade, Andrew M., Yang, Qin, Vladimirov, Georgy K., Philpott, Caroline C., Kagan, Valerian E.
Published in Cell chemical biology (16.04.2020)
Published in Cell chemical biology (16.04.2020)
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Fatty acid transport protein 2 reprograms neutrophils in cancer
Veglia, Filippo, Tyurin, Vladimir A., Blasi, Maria, De Leo, Alessandra, Kossenkov, Andrew V., Donthireddy, Laxminarasimha, To, Tsun Ki Jerrick, Schug, Zach, Basu, Subhasree, Wang, Fang, Ricciotti, Emanuela, DiRusso, Concetta, Murphy, Maureen E., Vonderheide, Robert H., Lieberman, Paul M., Mulligan, Charles, Nam, Brian, Hockstein, Neil, Masters, Gregory, Guarino, Michael, Lin, Cindy, Nefedova, Yulia, Black, Paul, Kagan, Valerian E., Gabrilovich, Dmitry I.
Published in Nature (London) (01.05.2019)
Published in Nature (London) (01.05.2019)
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Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
Kagan, Valerian E, Mao, Gaowei, Qu, Feng, Angeli, Jose Pedro Friedmann, Doll, Sebastian, Croix, Claudette St, Dar, Haider Hussain, Liu, Bing, Tyurin, Vladimir A, Ritov, Vladimir B, Kapralov, Alexandr A, Amoscato, Andrew A, Jiang, Jianfei, Anthonymuthu, Tamil, Mohammadyani, Dariush, Yang, Qin, Proneth, Bettina, Klein-Seetharaman, Judith, Watkins, Simon, Bahar, Ivet, Greenberger, Joel, Mallampalli, Rama K, Stockwell, Brent R, Tyurina, Yulia Y, Conrad, Marcus, Bayır, Hülya
Published in Nature chemical biology (01.01.2017)
Published in Nature chemical biology (01.01.2017)
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Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease
Stockwell, Brent R., Friedmann Angeli, José Pedro, Bayir, Hülya, Bush, Ashley I., Conrad, Marcus, Dixon, Scott J., Fulda, Simone, Gascón, Sergio, Hatzios, Stavroula K., Kagan, Valerian E., Noel, Kay, Jiang, Xuejun, Linkermann, Andreas, Murphy, Maureen E., Overholtzer, Michael, Oyagi, Atsushi, Pagnussat, Gabriela C., Park, Jason, Ran, Qitao, Rosenfeld, Craig S., Salnikow, Konstantin, Tang, Daolin, Torti, Frank M., Torti, Suzy V., Toyokuni, Shinya, Woerpel, K.A., Zhang, Donna D.
Published in Cell (05.10.2017)
Published in Cell (05.10.2017)
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Cardiolipin Interactions with Proteins
Planas-Iglesias, Joan, Dwarakanath, Himal, Mohammadyani, Dariush, Yanamala, Naveena, Kagan, Valerian E., Klein-Seetharaman, Judith
Published in Biophysical journal (15.09.2015)
Published in Biophysical journal (15.09.2015)
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Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis
Wiernicki, Bartosz, Dubois, Hanne, Tyurina, Yulia Y., Hassannia, Behrouz, Bayir, Hülya, Kagan, Valerian E., Vandenabeele, Peter, Wullaert, Andy, Vanden Berghe, Tom
Published in Cell death & disease (27.10.2020)
Published in Cell death & disease (27.10.2020)
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Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
Hassannia, Behrouz, Wiernicki, Bartosz, Ingold, Irina, Qu, Feng, Van Herck, Simon, Tyurina, Yulia Y, Bayır, Hülya, Abhari, Behnaz A, Angeli, Jose Pedro Friedmann, Choi, Sze Men, Meul, Eline, Heyninck, Karen, Declerck, Ken, Chirumamilla, Chandra Sekhar, Lahtela-Kakkonen, Maija, Van Camp, Guy, Krysko, Dmitri V, Ekert, Paul G, Fulda, Simone, De Geest, Bruno G, Conrad, Marcus, Kagan, Valerian E, Vanden Berghe, Wim, Vandenabeele, Peter, Vanden Berghe, Tom
Published in The Journal of clinical investigation (01.08.2018)
Published in The Journal of clinical investigation (01.08.2018)
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Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation
Li, Wenjun, Feng, Guoshuai, Gauthier, Jason M, Lokshina, Inessa, Higashikubo, Ryuji, Evans, Sarah, Liu, Xinping, Hassan, Adil, Tanaka, Satona, Cicka, Markus, Hsiao, Hsi-Min, Ruiz-Perez, Daniel, Bredemeyer, Andrea, Gross, Richard W, Mann, Douglas L, Tyurina, Yulia Y, Gelman, Andrew E, Kagan, Valerian E, Linkermann, Andreas, Lavine, Kory J, Kreisel, Daniel
Published in The Journal of clinical investigation (01.06.2019)
Published in The Journal of clinical investigation (01.06.2019)
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Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1
Beatty, Alexander, Singh, Tanu, Tyurina, Yulia Y., Tyurin, Vladimir A., Samovich, Svetlana, Nicolas, Emmanuelle, Maslar, Kristen, Zhou, Yan, Cai, Kathy Q., Tan, Yinfei, Doll, Sebastian, Conrad, Marcus, Subramanian, Aravind, Bayır, Hülya, Kagan, Valerian E., Rennefahrt, Ulrike, Peterson, Jeffrey R.
Published in Nature communications (14.04.2021)
Published in Nature communications (14.04.2021)
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Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis
Protchenko, Olga, Baratz, Ethan, Jadhav, Shyamalagauri, Li, Fengmin, Shakoury‐Elizeh, Minoo, Gavrilova, Oksana, Ghosh, Manik C., Cox, James E., Maschek, J. Alan, Tyurin, Vladimir A., Tyurina, Yulia Y., Bayir, Hülya, Aron, Allegra T., Chang, Christopher J., Kagan, Valerian E., Philpott, Caroline C.
Published in Hepatology (Baltimore, Md.) (01.03.2021)
Published in Hepatology (Baltimore, Md.) (01.03.2021)
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FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation
Gaschler, Michael M., Andia, Alexander A., Liu, Hengrui, Csuka, Joleen M., Hurlocker, Brisa, Vaiana, Christopher A., Heindel, Daniel W., Zuckerman, Dylan S., Bos, Pieter H., Reznik, Eduard, Ye, Ling F., Tyurina, Yulia Y., Lin, Annie J., Shchepinov, Mikhail S., Chan, Amy Y., Peguero-Pereira, Eveliz, Fomich, Maksim A., Daniels, Jacob. D., Bekish, Andrei V., Shmanai, Vadim V., Kagan, Valerian E., Mahal, Lara K., Woerpel, K. A., Stockwell, Brent R.
Published in Nature chemical biology (01.05.2018)
Published in Nature chemical biology (01.05.2018)
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PLA2G6 guards placental trophoblasts against ferroptotic injury
Beharier, Ofer, Tyurin, Vladimir A., Goff, Julie P., Guerrero-Santoro, Jennifer, Kajiwara, Kazuhiro, Chu, Tianjiao, Tyurina, Yulia Y., St Croix, Claudette M., Wallace, Callen T., Parry, Samuel, Parks, W. Tony, Kagan, Valerian E., Sadovsky, Yoel
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2020)
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Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils
Perego, Michela, Tyurin, Vladimir A, Tyurina, Yulia Y, Yellets, Jonathan, Nacarelli, Timothy, Lin, Cindy, Nefedova, Yulia, Kossenkov, Andrew, Liu, Qin, Sreedhar, Sreesha, Pass, Harvey, Roth, Johannes, Vogl, Thomas, Feldser, David, Zhang, Rugang, Kagan, Valerian E, Gabrilovich, Dmitry I
Published in Science translational medicine (02.12.2020)
Published in Science translational medicine (02.12.2020)
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Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer
Veglia, Filippo, Tyurin, Vladimir A., Mohammadyani, Dariush, Blasi, Maria, Duperret, Elizabeth K., Donthireddy, Laxminarasimha, Hashimoto, Ayumi, Kapralov, Alexandr, Amoscato, Andrew, Angelini, Roberto, Patel, Sima, Alicea-Torres, Kevin, Weiner, David, Murphy, Maureen E., Klein-Seetharaman, Judith, Celis, Esteban, Kagan, Valerian E., Gabrilovich, Dmitry I.
Published in Nature communications (14.12.2017)
Published in Nature communications (14.12.2017)
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Necroptotic cell death in anti‐cancer therapy
Krysko, Olga, Aaes, Tania Løve, Kagan, Valerian E., D'Herde, Katharina, Bachert, Claus, Leybaert, Luc, Vandenabeele, Peter, Krysko, Dmitri V.
Published in Immunological reviews (01.11.2017)
Published in Immunological reviews (01.11.2017)
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Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
Chu, Charleen T., Ji, Jing, Dagda, Ruben K., Jiang, Jian Fei, Tyurina, Yulia Y., Kapralov, Alexandr A., Tyurin, Vladimir A., Yanamala, Naveena, Shrivastava, Indira H., Mohammadyani, Dariush, Qiang Wang, Kent Zhi, Zhu, Jianhui, Klein-Seetharaman, Judith, Balasubramanian, Krishnakumar, Amoscato, Andrew A., Borisenko, Grigory, Huang, Zhentai, Gusdon, Aaron M., Cheikhi, Amin, Steer, Erin K., Wang, Ruth, Baty, Catherine, Watkins, Simon, Bahar, Ivet, Bayır, Hülya, Kagan, Valerian E.
Published in Nature cell biology (01.10.2013)
Published in Nature cell biology (01.10.2013)
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Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes
Jang, Sehwan, Chapa-Dubocq, Xavier R., Tyurina, Yulia Y., St Croix, Claudette M., Kapralov, Alexandr A., Tyurin, Vladimir A., Bayır, Hülya, Kagan, Valerian E., Javadov, Sabzali
Published in Redox biology (01.09.2021)
Published in Redox biology (01.09.2021)
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