Employing a gain-of-function factor IX variant R338L to advance the efficacy and safety of hemophilia B human gene therapy: preclinical evaluation supporting an ongoing adeno-associated virus clinical trial
Monahan, Paul E, Sun, Junjiang, Gui, Tong, Hu, Genlin, Hannah, William B, Wichlan, David G, Wu, Zhijian, Grieger, Joshua C, Li, Chengwen, Suwanmanee, Thipparat, Stafford, Darrel W, Booth, Carmen J, Samulski, Jade J, Kafri, Tal, McPhee, Scott W J, Samulski, R Jude
Published in Human gene therapy (01.02.2015)
Published in Human gene therapy (01.02.2015)
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Harnessing the Anti-Tumor Mediators in Mast Cells as a New Strategy for Adoptive Cell Transfer for Cancer
Fereydouni, Mohammad, Motaghed, Mona, Ahani, Elnaz, Kafri, Tal, Dellinger, Kristen, Metcalfe, Dean D, Kepley, Christopher L
Published in Frontiers in oncology (31.03.2022)
Published in Frontiers in oncology (31.03.2022)
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Human Tumor Targeted Cytotoxic Mast Cells for Cancer Immunotherapy
Fereydouni, Mohammad, Ahani, Elnaz, Desai, Parth, Motaghed, Mona, Dellinger, Anthony, Metcalfe, Dean D, Yin, Yuzhi, Lee, Sung Hyun, Kafri, Tal, Bhatt, Aadra P, Dellinger, Kristen, Kepley, Christopher L
Published in Frontiers in oncology (22.04.2022)
Published in Frontiers in oncology (22.04.2022)
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Pharmacokinetics and efficacy of PEGylated liposomal doxorubicin in an intracranial model of breast cancer
Anders, Carey K, Adamo, Barbara, Karginova, Olga, Deal, Allison M, Rawal, Sumit, Darr, David, Schorzman, Allison, Santos, Charlene, Bash, Ryan, Kafri, Tal, Carey, Lisa, Miller, C Ryan, Perou, Charles M, Sharpless, Norman, Zamboni, William C
Published in PloS one (01.05.2013)
Published in PloS one (01.05.2013)
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Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection
Kantor, Boris, Ma, Hong, Webster-Cyriaque, Jennifer, Monahan, Paul E, Kafri, Tal
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2009)
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A Single Synonymous Variant (c.354G>A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity
Hunt, Ryan, Hettiarachchi, Gaya, Katneni, Upendra, Hernandez, Nancy, Holcomb, David, Kames, Jacob, Alnifaidy, Redab, Lin, Brian, Hamasaki-Katagiri, Nobuko, Wesley, Aaron, Kafri, Tal, Morris, Christina, Bouché, Laura, Panico, Maria, Schiller, Tal, Ibla, Juan, Bar, Haim, Ismail, Amra, Morris, Howard, Komar, Anton, Kimchi-Sarfaty, Chava
Published in International journal of molecular sciences (15.11.2019)
Published in International journal of molecular sciences (15.11.2019)
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Short Hairpin RNA-Mediated Knockdown of VEGFA in Müller Cells Reduces Intravitreal Neovascularization in a Rat Model of Retinopathy of Prematurity
Wang, Haibo, Smith, George W, Yang, Zhihong, Jiang, Yanchao, McCloskey, Manabu, Greenberg, Kenneth, Geisen, Pete, Culp, William D, Flannery, John, Kafri, Tal, Hammond, Scott, Hartnett, M. Elizabeth
Published in The American journal of pathology (01.09.2013)
Published in The American journal of pathology (01.09.2013)
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Proteasome Inhibitors Enhance Gene Delivery by AAV Virus Vectors Expressing Large Genomes in Hemophilia Mouse and Dog Models: A Strategy for Broad Clinical Application
Monahan, Paul E, Lothrop, Clinton D, Sun, Junjiang, Hirsch, Matthew L, Kafri, Tal, Kantor, Boris, Sarkar, Rita, Tillson, D Michael, Elia, Joseph R, Samulski, R Jude
Published in Molecular therapy (01.11.2010)
Published in Molecular therapy (01.11.2010)
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A Large U3 Deletion Causes Increased In Vivo Expression From a Nonintegrating Lentiviral Vector
Bayer, Matthew, Kantor, Boris, Cockrell, Adam, Ma, Hong, Zeithaml, Brian, Li, Xiangping, McCown, Thomas, Kafri, Tal
Published in Molecular therapy (01.12.2008)
Published in Molecular therapy (01.12.2008)
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Adeno-Associated Virus Type 2 (AAV2) Capsid-Specific Cytotoxic T Lymphocytes Eliminate Only Vector-Transduced Cells Coexpressing the AAV2 Capsid In Vivo
CHENGWEN LI, HIRSCH, Matthew, ASOKAN, Aravind, ZEITHAML, Brian, HONG MA, KAFRI, Tal, SAMUISKI, R. Jude
Published in Journal of Virology (01.07.2007)
Published in Journal of Virology (01.07.2007)
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Evolutionary etiology of high-grade astrocytomas
Song, Yurong, Zhang, Qian, Kutlu, Burak, Difilippantonio, Simone, Bash, Ryan, Gilbert, Debra, Yin, Chaoying, O'Sullivan, T. Norene, Yang, Chunyu, Kozlov, Serguei, Bullitt, Elizabeth, McCarthy, Ken D., Kafri, Tal, Louis, David N., Miller, C. Ryan, Hood, Leroy, Van Dyke, Terry
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2013)
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CCR5 Gene Editing of Resting CD4+ T Cells by Transient ZFN Expression From HIV Envelope Pseudotyped Nonintegrating Lentivirus Confers HIV-1 Resistance in Humanized Mice
Yi, Guohua, Choi, Jang Gi, Bharaj, Preeti, Abraham, Sojan, Dang, Ying, Kafri, Tal, Alozie, Ogechika, Manjunath, Manjunath N, Shankar, Premlata
Published in Molecular therapy. Nucleic acids (30.09.2014)
Published in Molecular therapy. Nucleic acids (30.09.2014)
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AAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis
Johnson, Jarrod S, Gentzsch, Martina, Zhang, Liqun, Ribeiro, Carla M P, Kantor, Boris, Kafri, Tal, Pickles, Raymond J, Samulski, R Jude
Published in PLoS pathogens (01.05.2011)
Published in PLoS pathogens (01.05.2011)
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Cellular Immune Response to Adenoviral Vector Infected Cells Does not Require de novo Viral Gene Expression: Implications for Gene Therapy
Kafri, Tal, Morgan, David, Krahl, Troy, Sarvetnick, Nora, Sherman, Linda, Verma, Inder
Published in Proceedings of the National Academy of Sciences - PNAS (15.09.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (15.09.1998)
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Toward Personalized Gene Therapy: Characterizing the Host Genetic Control of Lentiviral-Vector-Mediated Hepatic Gene Delivery
Suwanmanee, Thipparat, Ferris, Martin T, Hu, Peirong, Gui, Tong, Montgomery, Stephanie A, Pardo-Manuel de Villena, Fernando, Kafri, Tal
Published in Molecular therapy. Methods & clinical development (16.06.2017)
Published in Molecular therapy. Methods & clinical development (16.06.2017)
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Dominant-negative androgen receptor inhibition of intracrine androgen-dependent growth of castration-recurrent prostate cancer
Titus, Mark A, Zeithaml, Brian, Kantor, Boris, Li, Xiangping, Haack, Karin, Moore, Dominic T, Wilson, Elizabeth M, Mohler, James L, Kafri, Tal
Published in PloS one (17.01.2012)
Published in PloS one (17.01.2012)
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A Packaging Cell Line for Lentivirus Vectors
Kafri, T, van Praag, H, Ouyang, L, Gage, F H, Verma, I M
Published in Journal of Virology (01.01.1999)
Published in Journal of Virology (01.01.1999)
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