The Methylation Effect in Medicinal Chemistry
Barreiro, Eliezer J, Kümmerle, Arthur E, Fraga, Carlos A. M
Published in Chemical reviews (14.09.2011)
Published in Chemical reviews (14.09.2011)
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Journal Article
Multicomponent Reactions for the Synthesis of Bioactive Compounds: A Review
Graebin, Cedric S, Ribeiro, Felipe V, Rogério, Kamilla R, Kümmerle, Arthur E
Published in Current organic synthesis (01.01.2019)
Published in Current organic synthesis (01.01.2019)
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Journal Article
Characterization of amide bond conformers for a novel heterocyclic template of N-acylhydrazone derivatives
Lopes, Alexandra Basilio, Miguez, Eduardo, Kümmerle, Arthur Eugen, Rumjanek, Victor Marcos, Fraga, Carlos Alberto Manssour, Barreiro, Eliezer J
Published in Molecules (Basel, Switzerland) (25.09.2013)
Published in Molecules (Basel, Switzerland) (25.09.2013)
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Journal Article
The long and winding road of designing phosphodiesterase inhibitors for the treatment of heart failure
Nadur, Nathalia Fonseca, de Azevedo, Luciana Luiz, Caruso, Lucas, Graebin, Cedric Stephan, Lacerda, Renata Barbosa, Kümmerle, Arthur Eugen
Published in European journal of medicinal chemistry (15.02.2021)
Published in European journal of medicinal chemistry (15.02.2021)
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Journal Article
Design, Synthesis, and Pharmacological Evaluation of N‑Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase‑4 Inhibitors
Kümmerle, Arthur E, Schmitt, Martine, Cardozo, Suzana V. S, Lugnier, Claire, Villa, Pascal, Lopes, Alexandra B, Romeiro, Nelilma C, Justiniano, Hélène, Martins, Marco A, Fraga, Carlos A. M, Bourguignon, Jean-Jacques, Barreiro, Eliezer J
Published in Journal of medicinal chemistry (13.09.2012)
Published in Journal of medicinal chemistry (13.09.2012)
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Journal Article
Quinolone-N-acylhydrazone hybrids as potent Zika and Chikungunya virus inhibitors
Marra, Roberta K.F., Kümmerle, Arthur E., Guedes, Guilherme P., Barros, Caroline de S., Gomes, Rafaela S.P., Cirne-Santos, Claudio C., Paixão, Izabel Christina N.P., Neves, Amanda P.
Published in Bioorganic & medicinal chemistry letters (15.01.2020)
Published in Bioorganic & medicinal chemistry letters (15.01.2020)
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Journal Article
Design, Synthesis and Biological Evaluation of Novel Triazole N -acylhydrazone Hybrids for Alzheimer's Disease
de Freitas Silva, Matheus, Tardelli Lima, Ellen, Pruccoli, Letizia, Castro, Newton G, Guimarães, Marcos Jorge R, M R da Silva, Fernanda, Fonseca Nadur, Nathalia, de Azevedo, Luciana Luiz, Kümmerle, Arthur Eugen, Guedes, Isabella Alvim, Dardenne, Laurent Emmanuel, Gontijo, Vanessa Silva, Tarozzi, Andrea, Viegas, Claudio
Published in Molecules (Basel, Switzerland) (10.07.2020)
Published in Molecules (Basel, Switzerland) (10.07.2020)
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Journal Article
Novel Co III complexes containing fluorescent coumarin-N-acylhydrazone hybrid ligands: Synthesis, crystal structures, solution studies and DFT calculations
Areas, Esther S, Bronsato, Bruna Juliana da S, Pereira, Thiago M, Guedes, Guilherme P, Miranda, Fábio da S, Kümmerle, Arthur E, da Cruz, Antônio G B, Neves, Amanda P
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05.12.2017)
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05.12.2017)
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Journal Article
MICROWAVE-ASSISTED SYNTHESIS AND PKA DETERMINATION OF UMBELLIFERONE: AN EXPERIMENT FOR THE UNDERGRADUATE ORGANIC CHEMISTRY LABORATORY
Pereira, Thiago, Franco, Daiana, Vitório, Felipe, Amaral, Ronaldo, Ponzoni, Aparecida, Kümmerle, Arthur
Published in Química Nova (01.12.2018)
Published in Química Nova (01.12.2018)
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Journal Article
Structure-Based Discovery of Thiosemicarbazone Metalloproteinase Inhibitors for Hemorrhage Treatment in Snakebites
Ferreira, Francis B, Pereira, Thiago M, Souza, Dayane L. N, Lopes, Daiana S, Freitas, Vitor, Ávila, Veridiana M. R, Kümmerle, Arthur E, Sant’Anna, Carlos Mauricio R
Published in ACS medicinal chemistry letters (09.11.2017)
Published in ACS medicinal chemistry letters (09.11.2017)
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Journal Article
Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant
de Souza, Gabriela Alves, da Silva, Soraia John, Del Cistia, Catarina de Nigris, Pitasse-Santos, Paulo, Pires, Lucas de Oliveira, Passos, Yulli Moraes, Cordeiro, Yraima, Cardoso, Cristiane Martins, Castro, Rosane Nora, Sant'Anna, Carlos Mauricio R., Kümmerle, Arthur Eugen
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2019)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2019)
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Journal Article
Beneficial effects of a novel agonist of the adenosine A2A receptor on monocrotaline‐induced pulmonary hypertension in rats
Alencar, Allan K N, Pereira, Sharlene L, Montagnoli, Tadeu L, Maia, Rodolfo C, Kümmerle, Arthur E, Landgraf, Sharon S, Caruso‐Neves, Celso, Ferraz, Emanuelle B, Tesch, Roberta, Nascimento, José H M, Sant'Anna, Carlos M R, Fraga, Carlos A M, Barreiro, Eliezer J, Sudo, Roberto T, Zapata‐Sudo, Gisele
Published in British journal of pharmacology (01.07.2013)
Published in British journal of pharmacology (01.07.2013)
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Journal Article
Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives
Kümmerle, Arthur E., Raimundo, Juliana M., Leal, Carla M., da Silva, Givanildo S., Balliano, Tatiane L., Pereira, Mariano A., de Simone, Carlos A., Sudo, Roberto T., Zapata-Sudo, Gisele, Fraga, Carlos A.M., Barreiro, Eliezer J.
Published in European journal of medicinal chemistry (01.10.2009)
Published in European journal of medicinal chemistry (01.10.2009)
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Journal Article
Access to 4‑Alkylaminopyridazine Derivatives via Nitrogen-Assisted Regioselective Pd-Catalyzed Reactions
Blaise, Emilie, Kümmerle, Arthur E, Hammoud, Hassan, de Araújo-Júnior, João Xavier, Bihel, Frédéric, Bourguignon, Jean-Jacques, Schmitt, Martine
Published in Journal of organic chemistry (07.11.2014)
Published in Journal of organic chemistry (07.11.2014)
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Journal Article
Theory Behind Biginelli Reaction Revisited
Nicola Tejero, Tatiane, Eugen Kümmerle, Arthur, Favilla Bauerfeldt, Glauco
Published in Revista Virtual de Química (01.07.2019)
Published in Revista Virtual de Química (01.07.2019)
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Journal Article
Structural insights into cholinesterases inhibition by harmane β-carbolinium derivatives: A kinetics – molecular modeling approach
Torres, Juliana M., Lira, Aline F., Silva, Daniel R., Guzzo, Lucas M., Sant’Anna, Carlos M.R., Kümmerle, Arthur E., Rumjanek, Victor M.
Published in Phytochemistry (Oxford) (01.09.2012)
Published in Phytochemistry (Oxford) (01.09.2012)
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Journal Article
Butyrylcholinesterase - BuChE: A Potential Target for Development of Drugs for Alzheimer's Disease Treatment
do N. Goulart, Paula, Caruso, Lucas, F. Nadur, Nathália, P. Franco, Daiana, E. Kümmerle, Arthur, B. Lacerda, Renata
Published in Revista Virtual de Química (2021)
Published in Revista Virtual de Química (2021)
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Journal Article