Delphi studies in social and health sciences-Recommendations for an interdisciplinary standardized reporting (DELPHISTAR). Results of a Delphi study
Niederberger, Marlen, Schifano, Julia, Deckert, Stefanie, Hirt, Julian, Homberg, Angelika, Köberich, Stefan, Kuhn, Rainer, Rommel, Alexander, Sonnberger, Marco
Published in PloS one (26.08.2024)
Published in PloS one (26.08.2024)
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LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice
Herzig, Martin C., Kolly, Carine, Persohn, Elke, Theil, Diethilde, Schweizer, Tatjana, Hafner, Thomas, Stemmelen, Christine, Troxler, Thomas J., Schmid, Peter, Danner, Simone, Schnell, Christian R., Mueller, Matthias, Kinzel, Bernd, Grevot, Armelle, Bolognani, Federico, Stirn, Martina, Kuhn, Rainer R., Kaupmann, Klemens, van der Putten, P. Herman, Rovelli, Giorgio, Shimshek, Derya R.
Published in Human molecular genetics (01.11.2011)
Published in Human molecular genetics (01.11.2011)
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Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis
Dev, Kumlesh K, Mullershausen, Florian, Mattes, Henri, Kuhn, Rainer R, Bilbe, Graeme, Hoyer, Daniel, Mir, Anis
Published in Pharmacology & therapeutics (Oxford) (01.01.2008)
Published in Pharmacology & therapeutics (Oxford) (01.01.2008)
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LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice
HERZIG, Martin C, KOLLY, Carine, SCHNELL, Christian R, MUELLER, Matthias, KINZEL, Bernd, GREVOT, Armelle, BOLOGNANI, Federico, STIRN, Martina, KUHN, Rainer R, KAUPMANN, Klemens, VAN DER PUTTEN, P. Herman, ROVELLI, Giorgio, PERSOHN, Elke, SHIMSHEK, Derya R, THEIL, Diethilde, SCHWEIZER, Tatjana, HAFNER, Thomas, STEMMELEN, Christine, TROXLER, Thomas J, SCHMID, Peter, DANNER, Simone
Published in Human molecular genetics (01.11.2011)
Published in Human molecular genetics (01.11.2011)
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A Selective Metabotropic Glutamate Receptor 7 Agonist: Activation of Receptor Signaling via an Allosteric Site Modulates Stress Parameters In vivo
Kayo Mitsukawa, Rina Yamamoto, Silvio Ofner, Joachim Nozulak, Oliver Pescott, Snezana Lukic, Natacha Stoehr, Cedric Mombereau, Kuhn, Rainer, Kevin H. Mc Allister, van der Putten, Herman, Cryan, John F., Peter J. Flor, Scolnick, Edward M.
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2005)
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Fragments of HdhQ150 mutant huntingtin form a soluble oligomer pool that declines with aggregate deposition upon aging
Marcellin, David, Abramowski, Dorothee, Young, Douglas, Richter, Jens, Weiss, Andreas, Marcel, Audrey, Maassen, Julia, Kauffmann, Muriel, Bibel, Miriam, Shimshek, Derya R, Faull, Richard L M, Bates, Gillian P, Kuhn, Rainer R, Van der Putten, P Herman, Schmid, Peter, Lotz, Gregor P
Published in PloS one (12.09.2012)
Published in PloS one (12.09.2012)
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Polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopy
Fodale, Valentina, Kegulian, Natalie C, Verani, Margherita, Cariulo, Cristina, Azzollini, Lucia, Petricca, Lara, Daldin, Manuel, Boggio, Roberto, Padova, Alessandro, Kuhn, Rainer, Pacifici, Robert, Macdonald, Douglas, Schoenfeld, Ryan C, Park, Hyunsun, Isas, J Mario, Langen, Ralf, Weiss, Andreas, Caricasole, Andrea
Published in PloS one (02.12.2014)
Published in PloS one (02.12.2014)
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Atg4b-dependent autophagic flux alleviates Huntington's disease progression
Proenca, Catia C, Stoehr, Natacha, Bernhard, Mario, Seger, Shanon, Genoud, Christel, Roscic, Ana, Paganetti, Paolo, Liu, Shanming, Murphy, Leon O, Kuhn, Rainer, Bouwmeester, Tewis, Galimberti, Ivan
Published in PloS one (08.07.2013)
Published in PloS one (08.07.2013)
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Potential anxiolytic‐ and antidepressant‐like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist
Tatarczyńska, Ewa, Kłodzińska, Aleksandra, Chojnacka‐Wójcik, Ewa, Pałucha, Agnieszka, Gasparini, Fabrizio, Kuhn, Rainer, Pilc, Andrzej
Published in British journal of pharmacology (01.04.2001)
Published in British journal of pharmacology (01.04.2001)
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Anxiolytic-Like Effects of the Prototypical Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)pyridine in Rodents
Spooren, W P, Vassout, A, Neijt, H C, Kuhn, R, Gasparini, F, Roux, S, Porsolt, R D, Gentsch, C
Published in The Journal of pharmacology and experimental therapeutics (01.12.2000)
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Published in The Journal of pharmacology and experimental therapeutics (01.12.2000)
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The Non-competitive Antagonists 2-Methyl-6-(phenylethynyl)pyridine and 7-Hydroxyiminocyclopropan[b]chromen-1a-carboxylic Acid Ethyl Ester Interact with Overlapping Binding Pockets in the Transmembrane Region of Group I Metabotropic Glutamate Receptors
Pagano, Adriana, Rüegg, Doris, Litschig, Stephane, Stoehr, Natacha, Stierlin, Christine, Heinrich, Micheline, Floersheim, Philipp, Prezèau, Laurent, Carroll, Fiona, Pin, Jean-Philippe, Cambria, Antonio, Vranesic, Ivo, Flor, Peter Josef, Gasparini, Fabrizio, Kuhn, Rainer
Published in The Journal of biological chemistry (27.10.2000)
Published in The Journal of biological chemistry (27.10.2000)
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CPCCOEt, a Noncompetitive Metabotropic Glutamate Receptor 1 Antagonist, Inhibits Receptor Signaling Without Affecting Glutamate Binding
Litschig, S, Gasparini, F, Rueegg, D, Stoehr, N, Flor, P J, Vranesic, I, Prézeau, L, Pin, J P, Thomsen, C, Kuhn, R
Published in Molecular pharmacology (01.03.1999)
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Published in Molecular pharmacology (01.03.1999)
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Relaxation of human ureteral smooth muscle in vitro by modulation of cyclic nucleotide-dependent pathways
Kühn, R, Uckert, S, Stief, C G, Truss, M C, Lietz, B, Bischoff, E, Schramm, M, Jonas, U
Published in Urolithiasis (01.04.2000)
Published in Urolithiasis (01.04.2000)
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Effects of the prototypical mGlu5 receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine on rotarod, locomotor activity and rotational responses in unilateral 6-OHDA-lesioned rats
SPOOREN, Will P. J. M, GASPARINI, Fabrizio, BERGMANN, Reinhard, KUHN, Rainer
Published in European journal of pharmacology (01.10.2000)
Published in European journal of pharmacology (01.10.2000)
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Journal Article
Increased Seizure Susceptibility in Mice Lacking Metabotropic Glutamate Receptor 7
Sansig, Gilles, Bushell, Trevor J, Clarke, Vernon R. J, Rozov, Andrei, Burnashev, Nail, Portet, Chantal, Gasparini, Fabrizio, Schmutz, Markus, Klebs, Klaus, Shigemoto, Ryuichi, Flor, Peter J, Kuhn, Rainer, Knoepfel, Thomas, Schroeder, Markus, Hampson, David R, Collett, Valerie J, Zhang, Congxiao, Duvoisin, Robert M, Collingridge, Graham L, van der Putten, Herman
Published in The Journal of neuroscience (15.11.2001)
Published in The Journal of neuroscience (15.11.2001)
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Metabotropic Glutamate Receptor 5 Upregulation in A-Fibers after Spinal Nerve Injury: 2-Methyl-6-(Phenylethynyl)-Pyridine (MPEP) Reverses the Induced Thermal Hyperalgesia
Hudson, Lindsey J, Bevan, Stuart, McNair, Kara, Gentry, Clive, Fox, Alyson, Kuhn, Rainer, Winter, Janet
Published in The Journal of neuroscience (01.04.2002)
Published in The Journal of neuroscience (01.04.2002)
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Journal Article
Metabotropic Glutamate Receptors: Novel Targets for Drug Development
Knoepfel, Thomas, Kuhn, Rainer, Allgeier, Hans
Published in Journal of medicinal chemistry (01.04.1995)
Published in Journal of medicinal chemistry (01.04.1995)
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Journal Article
SIB-1757 and SIB-1893: Selective, Noncompetitive Antagonists of Metabotropic Glutamate Receptor Type 5
Varney, M A, Cosford, N D, Jachec, C, Rao, S P, Sacaan, A, Lin, F F, Bleicher, L, Santori, E M, Flor, P J, Allgeier, H, Gasparini, F, Kuhn, R, Hess, S D, Veliçelebi, G, Johnson, E C
Published in The Journal of pharmacology and experimental therapeutics (01.07.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.1999)
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