Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS
Park, Yong Hwan, Wood, Geryl, Kastner, Daniel L, Chae, Jae Jin
Published in Nature immunology (01.08.2016)
Published in Nature immunology (01.08.2016)
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The monogenic autoinflammatory diseases define new pathways in human innate immunity and inflammation
Manthiram, Kalpana, Zhou, Qing, Aksentijevich, Ivona, Kastner, Daniel L
Published in Nature immunology (01.08.2017)
Published in Nature immunology (01.08.2017)
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Journal Article
The Pyrin Inflammasome in Health and Disease
Schnappauf, Oskar, Chae, Jae Jin, Kastner, Daniel L, Aksentijevich, Ivona
Published in Frontiers in immunology (07.08.2019)
Published in Frontiers in immunology (07.08.2019)
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Journal Article
Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease ()
Masters, Seth L, Simon, Anna, Aksentijevich, Ivona, Kastner, Daniel L
Published in Annual review of immunology (01.01.2009)
Published in Annual review of immunology (01.01.2009)
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Journal Article
Consensus proposal for taxonomy and definition of the autoinflammatory diseases (AIDs): a Delphi study
Ben-Chetrit, Eldad, Gattorno, Marco, Gul, Ahmet, Kastner, Daniel L, Lachmann, Helen J, Touitou, Isabelle, Ruperto, Nicolino
Published in Annals of the rheumatic diseases (01.11.2018)
Published in Annals of the rheumatic diseases (01.11.2018)
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Quantitative sampling of atomic-scale electromagnetic waveforms
Peller, D., Roelcke, C., Kastner, L. Z., Buchner, T., Neef, A., Hayes, J., Bonafé, F., Sidler, D., Ruggenthaler, M., Rubio, A., Huber, R., Repp, J.
Published in Nature photonics (01.02.2021)
Published in Nature photonics (01.02.2021)
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Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
Bulua, Ariel C, Simon, Anna, Maddipati, Ravikanth, Pelletier, Martin, Park, Heiyoung, Kim, Kye-Young, Sack, Michael N, Kastner, Daniel L, Siegel, Richard M
Published in The Journal of experimental medicine (14.03.2011)
Published in The Journal of experimental medicine (14.03.2011)
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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Coll, Rebecca C, Robertson, Avril A B, Chae, Jae Jin, Higgins, Sarah C, Muñoz-Planillo, Raúl, Inserra, Marco C, Vetter, Irina, Dungan, Lara S, Monks, Brian G, Stutz, Andrea, Croker, Daniel E, Butler, Mark S, Haneklaus, Moritz, Sutton, Caroline E, Núñez, Gabriel, Latz, Eicke, Kastner, Daniel L, Mills, Kingston H G, Masters, Seth L, Schroder, Kate, Cooper, Matthew A, O'Neill, Luke A J
Published in Nature medicine (01.03.2015)
Published in Nature medicine (01.03.2015)
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Journal Article
The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome
Chung, Lawton K., Park, Yong Hwan, Zheng, Yueting, Brodsky, Igor E., Hearing, Patrick, Kastner, Daniel L., Chae, Jae Jin, Bliska, James B.
Published in Cell host & microbe (14.09.2016)
Published in Cell host & microbe (14.09.2016)
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Journal Article
Old Dogs, New Tricks: Monogenic Autoinflammatory Disease Unleashed
Stoffels, Monique, Kastner, Daniel L
Published in Annual review of genomics and human genetics (31.08.2016)
Published in Annual review of genomics and human genetics (31.08.2016)
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Journal Article
Gain-of-Function Pyrin Mutations Induce NLRP3 Protein -Independent Interleukin-1β Activation and Severe Autoinflammation in Mice
Chae, Jae Jin, Cho, Young-Hun, Lee, Geun-Shik, Cheng, Jun, Liu, P. Paul, Feigenbaum, Lionel, Katz, Stephen I., Kastner, Daniel L.
Published in Immunity (Cambridge, Mass.) (27.05.2011)
Published in Immunity (Cambridge, Mass.) (27.05.2011)
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Journal Article
Treatment Strategies for Deficiency of Adenosine Deaminase 2
Ombrello, Amanda K, Qin, Jing, Hoffmann, Patrycja M, Kumar, Parag, Stone, Deborah, Jones, Anne, Romeo, Tina, Barham, Beverly, Pinto-Patarroyo, Gineth, Toro, Camilo, Soldatos, Ariane, Zhou, Qing, Deuitch, Natalie, Aksentijevich, Ivona, Sheldon, Sherry L, Kelly, Susan, Man, Ada, Barron, Karyl, Hershfield, Michael, Flegel, Willy A, Kastner, Daniel L
Published in The New England journal of medicine (18.04.2019)
Published in The New England journal of medicine (18.04.2019)
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Journal Article
Lighting the fires within: the cell biology of autoinflammatory diseases
Park, Heiyoung, Bourla, Ariel Bulua, Kastner, Daniel L., Colbert, Robert A., Siegel, Richard M.
Published in Nature reviews. Immunology (01.08.2012)
Published in Nature reviews. Immunology (01.08.2012)
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Journal Article
Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease
Zhou, Qing, Yu, Xiaomin, Demirkaya, Erkan, Deuitch, Natalie, Stone, Deborah, Tsai, Wanxia Li, Kuehn, Hye Sun, Wang, Hongying, Yang, Dan, Park, Yong Hwan, Ombrello, Amanda K., Blake, Mary, Romeo, Tina, Remmers, Elaine F., Chae, Jae Jin, Mullikin, James C., Güzel, Ferhat, Milner, Joshua D., Boehm, Manfred, Rosenzweig, Sergio D., Gadina, Massimo, Welch, Steven B., Özen, Seza, Topaloglu, Rezan, Abinun, Mario, Kastner, Daniel L., Aksentijevich, Ivona
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2016)
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Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages
Sokolowska, Milena, Chen, Li-Yuan, Liu, Yueqin, Martinez-Anton, Asuncion, Qi, Hai-Yan, Logun, Carolea, Alsaaty, Sara, Park, Yong Hwan, Kastner, Daniel L, Chae, Jae Jin, Shelhamer, James H
Published in The Journal of immunology (1950) (01.06.2015)
Published in The Journal of immunology (1950) (01.06.2015)
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Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B51 and ERAP1
Kirino, Yohei, Bertsias, George, Ishigatsubo, Yoshiaki, Mizuki, Nobuhisa, Tugal-Tutkun, Ilknur, Seyahi, Emire, Ozyazgan, Yilmaz, Sacli, F Sevgi, Erer, Burak, Inoko, Hidetoshi, Emrence, Zeliha, Cakar, Atilla, Abaci, Neslihan, Ustek, Duran, Satorius, Colleen, Ueda, Atsuhisa, Takeno, Mitsuhiro, Kim, Yoonhee, Wood, Geryl M, Ombrello, Michael J, Meguro, Akira, Gül, Ahmet, Remmers, Elaine F, Kastner, Daniel L
Published in Nature genetics (01.02.2013)
Published in Nature genetics (01.02.2013)
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Journal Article
Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis
Park, Yong Hwan, Remmers, Elaine F., Lee, Wonyong, Ombrello, Amanda K., Chung, Lawton K., Shilei, Zhao, Stone, Deborah L., Ivanov, Maya I., Loeven, Nicole A., Barron, Karyl S., Hoffmann, Patrycja, Nehrebecky, Michele, Akkaya-Ulum, Yeliz Z., Sag, Erdal, Balci-Peynircioglu, Banu, Aksentijevich, Ivona, Gül, Ahmet, Rotimi, Charles N., Chen, Hua, Bliska, James B., Ozen, Seza, Kastner, Daniel L., Shriner, Daniel, Chae, Jae Jin
Published in Nature immunology (01.08.2020)
Published in Nature immunology (01.08.2020)
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