Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
Robbins, Paul D, Jurk, Diana, Khosla, Sundeep, Kirkland, James L, LeBrasseur, Nathan K, Miller, Jordan D, Passos, João F, Pignolo, Robert J, Tchkonia, Tamar, Niedernhofer, Laura J
Published in Annual review of pharmacology and toxicology (06.01.2021)
Published in Annual review of pharmacology and toxicology (06.01.2021)
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Journal Article
Which Way Do We Go? Complex Interactions in Atopic Dermatitis Pathogenesis
Patrick, Garrett J., Archer, Nathan K., Miller, Lloyd S.
Published in Journal of investigative dermatology (01.02.2021)
Published in Journal of investigative dermatology (01.02.2021)
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Journal Article
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
Saul, Dominik, Kosinsky, Robyn Laura, Atkinson, Elizabeth J., Doolittle, Madison L., Zhang, Xu, LeBrasseur, Nathan K., Pignolo, Robert J., Robbins, Paul D., Niedernhofer, Laura J., Ikeno, Yuji, Jurk, Diana, Passos, João F., Hickson, LaTonya J., Xue, Ailing, Monroe, David G., Tchkonia, Tamara, Kirkland, James L., Farr, Joshua N., Khosla, Sundeep
Published in Nature communications (16.08.2022)
Published in Nature communications (16.08.2022)
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Journal Article
Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity
Palmer, Allyson K, Tchkonia, Tamara, LeBrasseur, Nathan K, Chini, Eduardo N, Xu, Ming, Kirkland, James L
Published in Diabetes (New York, N.Y.) (01.07.2015)
Published in Diabetes (New York, N.Y.) (01.07.2015)
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Journal Article
Cellular senescence mediates fibrotic pulmonary disease
Schafer, Marissa J., White, Thomas A., Iijima, Koji, Haak, Andrew J., Ligresti, Giovanni, Atkinson, Elizabeth J., Oberg, Ann L., Birch, Jodie, Salmonowicz, Hanna, Zhu, Yi, Mazula, Daniel L., Brooks, Robert W., Fuhrmann-Stroissnigg, Heike, Pirtskhalava, Tamar, Prakash, Y. S., Tchkonia, Tamara, Robbins, Paul D., Aubry, Marie Christine, Passos, João F., Kirkland, James L., Tschumperlin, Daniel J., Kita, Hirohito, LeBrasseur, Nathan K.
Published in Nature communications (23.02.2017)
Published in Nature communications (23.02.2017)
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Journal Article
Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study
Justice, Jamie N., Nambiar, Anoop M., Tchkonia, Tamar, LeBrasseur, Nathan K., Pascual, Rodolfo, Hashmi, Shahrukh K., Prata, Larissa, Masternak, Michal M., Kritchevsky, Stephen B., Musi, Nicolas, Kirkland, James L.
Published in EBioMedicine (01.02.2019)
Published in EBioMedicine (01.02.2019)
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Journal Article
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
Xu, Ming, Tchkonia, Tamara, Ding, Husheng, Ogrodnik, Mikolaj, Lubbers, Ellen R., Pirtskhalava, Tamar, White, Thomas A., Johnson, Kurt O., Stout, Michael B., Mezera, Vojtech, Giorgadze, Nino, Jensen, Michael D., LeBrasseur, Nathan K., Kirkland, James L.
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2015)
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Journal Article
Identification of Senescent Cells in the Bone Microenvironment
Farr, Joshua N, Fraser, Daniel G, Wang, Haitao, Jaehn, Katharina, Ogrodnik, Mikolaj B, Weivoda, Megan M, Drake, Matthew T, Tchkonia, Tamara, LeBrasseur, Nathan K, Kirkland, James L, Bonewald, Lynda F, Pignolo, Robert J, Monroe, David G, Khosla, Sundeep
Published in Journal of bone and mineral research (01.11.2016)
Published in Journal of bone and mineral research (01.11.2016)
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Journal Article
Poison Exon Splicing Regulates a Coordinated Network of SR Protein Expression during Differentiation and Tumorigenesis
Leclair, Nathan K., Brugiolo, Mattia, Urbanski, Laura, Lawson, Shane C., Thakar, Ketan, Yurieva, Marina, George, Joshy, Hinson, John Travis, Cheng, Albert, Graveley, Brenton R., Anczuków, Olga
Published in Molecular cell (19.11.2020)
Published in Molecular cell (19.11.2020)
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Journal Article
Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice
Ogrodnik, Mikolaj, Evans, Shane A., Fielder, Edward, Victorelli, Stella, Kruger, Patrick, Salmonowicz, Hanna, Weigand, Bettina M., Patel, Ayush D., Pirtskhalava, Tamar, Inman, Christine L., Johnson, Kurt O., Dickinson, Stephanie L., Rocha, Azucena, Schafer, Marissa J., Zhu, Yi, Allison, David B., Zglinicki, Thomas, LeBrasseur, Nathan K., Tchkonia, Tamar, Neretti, Nicola, Passos, João F., Kirkland, James L., Jurk, Diana
Published in Aging cell (01.02.2021)
Published in Aging cell (01.02.2021)
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Journal Article
Testing general relativity using gravitational wave signals from the inspiral, merger and ringdown of binary black holes
Ghosh, Abhirup, Johnson-McDaniel, Nathan K, Ghosh, Archisman, Mishra, Chandra Kant, Ajith, Parameswaran, Pozzo, Walter Del, Berry, Christopher P L, Nielsen, Alex B, London, Lionel
Published in Classical and quantum gravity (11.01.2018)
Published in Classical and quantum gravity (11.01.2018)
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