Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals
Jurima-Romet, M, Crawford, K, Cyr, T, Inaba, T
Published in Drug metabolism and disposition (01.11.1994)
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Published in Drug metabolism and disposition (01.11.1994)
Journal Article
Making Better Drugs: Decision Gates in Non-Clinical Drug Development
Pritchard, J. Fred, Jurima-Romet, Malle, Reimer, Mark L. J, Mortimer, Elisabeth, Rolfe, Brenda, Cayen, Mitchell N
Published in Nature reviews. Drug discovery (01.07.2003)
Published in Nature reviews. Drug discovery (01.07.2003)
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Journal Article
Evidence for the catalysis of Dextromethorphan O-demethylation by a CYP2D6-like enzyme in pig liver
Jurima-Romet, M., Casley, W.L., Leblanc, C.A., Nowakowska, M.
Published in Toxicology in vitro (01.06.2000)
Published in Toxicology in vitro (01.06.2000)
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Journal Article
Induction of CYP3A and associated terfenadine N-dealkylation in rat hepatocytes cocultured with 3T3 cells
Jurima-Romet, M, Casley, W L, Neu, J M, Huang, H S
Published in Cell biology and toxicology (01.12.1995)
Published in Cell biology and toxicology (01.12.1995)
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Journal Article
Preclinical evaluation of drug—drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction
Li, Albert P., Maurel, Patrick, Gomez-Lechon, Maria Jose, Cheng, Larry C., Jurima-Romet, Malle
Published in Chemico-biological interactions (06.11.1997)
Published in Chemico-biological interactions (06.11.1997)
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Journal Article
Evaluation of antacid tablets and liquid in fasting and fed men and women
Thomson, A B, Pinchbeck, B, Kirdeikis, J, Kirdeikis, P, Zuk, L, Brunet, M K, Jurima-Romet, M, Murray, P E
Published in Clinical therapeutics (1988)
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Published in Clinical therapeutics (1988)
Journal Article
Cytochrome P4502C9 (CYP2C9) allele frequencies in Canadian Native Indian and Inuit populations
Gaedigk, Andrea, Casley, William L, Tyndale, Rachel F, Sellers, Edward M, Jurima-Romet, Malle, Leeder, J Steven
Published in Canadian journal of physiology and pharmacology (01.10.2001)
Published in Canadian journal of physiology and pharmacology (01.10.2001)
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Journal Article
Cytochrome P4502C9 (CYP2C9) allele frequencies in canadian Native Indian and Inuit populations
GAEDIGK, Andrea, CASLEY, William L, TYNDALE, Rachel F, SELLERS, Edward M, JURIMA-ROMET, Malle, LEEDER, J. Steven
Published in Canadian journal of physiology and pharmacology (01.10.2001)
Published in Canadian journal of physiology and pharmacology (01.10.2001)
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Journal Article
A cell-based assay for screening the uridine 5 ′-diphosphate–glucuronosyltransferase 1A inhibitory potential of new chemical entities
Padrós, Jaime, Chun, Donald, Chen, Liangfu, Rigolli, Pierre, Flarakos, Themis, Jurima-Romet, Mallé
Published in Analytical biochemistry (15.09.2003)
Published in Analytical biochemistry (15.09.2003)
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Journal Article
Drug Interactions: Perspectives of the Canadian Drugs Directorate
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Book Chapter
Journal Article