PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells
Israelsen, William J., Dayton, Talya L., Davidson, Shawn M., Fiske, Brian P., Hosios, Aaron M., Bellinger, Gary, Li, Jie, Yu, Yimin, Sasaki, Mika, Horner, James W., Burga, Laura N., Xie, Jianxin, Jurczak, Michael J., DePinho, Ronald A., Clish, Clary B., Jacks, Tyler, Kibbey, Richard G., Wulf, Gerburg M., Di Vizio, Dolores, Mills, Gordon B., Cantley, Lewis C., Vander Heiden, Matthew G.
Published in Cell (10.10.2013)
Published in Cell (10.10.2013)
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Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes
Perry, Rachel J., Camporez, João-Paulo G., Kursawe, Romy, Titchenell, Paul M., Zhang, Dongyan, Perry, Curtis J., Jurczak, Michael J., Abudukadier, Abulizi, Han, Myoung Sook, Zhang, Xian-Man, Ruan, Hai-Bin, Yang, Xiaoyong, Caprio, Sonia, Kaech, Susan M., Sul, Hei Sook, Birnbaum, Morris J., Davis, Roger J., Cline, Gary W., Petersen, Kitt Falk, Shulman, Gerald I.
Published in Cell (12.02.2015)
Published in Cell (12.02.2015)
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Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch
Cohen, Paul, Levy, Julia D., Zhang, Yingying, Frontini, Andrea, Kolodin, Dmitriy P., Svensson, Katrin J., Lo, James C., Zeng, Xing, Ye, Li, Khandekar, Melin J., Wu, Jun, Gunawardana, Subhadra C., Banks, Alexander S., Camporez, João Paulo G., Jurczak, Michael J., Kajimura, Shingo, Piston, David W., Mathis, Diane, Cinti, Saverio, Shulman, Gerald I., Seale, Patrick, Spiegelman, Bruce M.
Published in Cell (16.01.2014)
Published in Cell (16.01.2014)
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The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis
Dominy, John E., Lee, Yoonjin, Jedrychowski, Mark P., Chim, Helen, Jurczak, Michael J., Camporez, Joao Paulo, Ruan, Hai-Bin, Feldman, Jessica, Pierce, Kerry, Mostoslavsky, Raul, Denu, John M., Clish, Clary B., Yang, Xiaoyong, Shulman, Gerald I., Gygi, Steven P., Puigserver, Pere
Published in Molecular cell (28.12.2012)
Published in Molecular cell (28.12.2012)
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Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis
Weisel, Florian J., Mullett, Steven J., Elsner, Rebecca A., Menk, Ashley V., Trivedi, Nikita, Luo, Wei, Wikenheiser, Daniel, Hawse, William F., Chikina, Maria, Smita, Shuchi, Conter, Laura J., Joachim, Stephen M., Wendell, Stacy G., Jurczak, Michael J., Winkler, Thomas H., Delgoffe, Greg M., Shlomchik, Mark J.
Published in Nature immunology (01.03.2020)
Published in Nature immunology (01.03.2020)
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A Metabolic Basis for Endothelial-to-Mesenchymal Transition
Xiong, Jianhua, Kawagishi, Hiroyuki, Yan, Ye, Liu, Jie, Wells, Quinn S., Edmunds, Lia R., Fergusson, Maria M., Yu, Zu-Xi, Rovira, Ilsa I., Brittain, Evan L., Wolfgang, Michael J., Jurczak, Michael J., Fessel, Joshua P., Finkel, Toren
Published in Molecular cell (15.02.2018)
Published in Molecular cell (15.02.2018)
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Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis
Argemi, Josepmaria, Latasa, Maria U., Atkinson, Stephen R., Blokhin, Ilya O., Massey, Veronica, Gue, Joel P., Cabezas, Joaquin, Lozano, Juan J., Van Booven, Derek, Bell, Aaron, Cao, Sheng, Vernetti, Lawrence A., Arab, Juan P., Ventura-Cots, Meritxell, Edmunds, Lia R., Fondevila, Constantino, Stärkel, Peter, Dubuquoy, Laurent, Louvet, Alexandre, Odena, Gemma, Gomez, Juan L., Aragon, Tomas, Altamirano, Jose, Caballeria, Juan, Jurczak, Michael J., Taylor, D. Lansing, Berasain, Carmen, Wahlestedt, Claes, Monga, Satdarshan P., Morgan, Marsha Y., Sancho-Bru, Pau, Mathurin, Philippe, Furuya, Shinji, Lackner, Carolin, Rusyn, Ivan, Shah, Vijay H., Thursz, Mark R., Mann, Jelena, Avila, Matias A., Bataller, Ramon
Published in Nature communications (16.07.2019)
Published in Nature communications (16.07.2019)
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Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance
Petersen, Max C, Madiraju, Anila K, Gassaway, Brandon M, Marcel, Michael, Nasiri, Ali R, Butrico, Gina, Marcucci, Melissa J, Zhang, Dongyan, Abulizi, Abudukadier, Zhang, Xian-Man, Philbrick, William, Hubbard, Stevan R, Jurczak, Michael J, Samuel, Varman T, Rinehart, Jesse, Shulman, Gerald I
Published in The Journal of clinical investigation (01.11.2016)
Published in The Journal of clinical investigation (01.11.2016)
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Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice
Camporez, João-Paulo G., Petersen, Max C., Abudukadier, Abulizi, Moreira, Gabriela V., Jurczak, Michael J., Friedman, Glenn, Haqq, Christopher M., Petersen, Kitt Falk, Shulman, Gerald I.
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
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Development of insulin resistance in mice lacking PGC-1α in adipose tissues
Kleiner, Sandra, Mepani, Rina J, Laznik, Dina, Ye, Li, Jurczak, Michael J, Jornayvaz, Francois R, Estall, Jennifer L, Chatterjee Bhowmick, Diti, Shulman, Gerald I, Spiegelman, Bruce M
Published in Proceedings of the National Academy of Sciences - PNAS (12.06.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (12.06.2012)
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Reduced mitophagy is an early feature of NAFLD and liver-specific PARKIN knockout hastens the onset of steatosis, inflammation and fibrosis
Undamatla, R., Fagunloye, O. G., Chen, J., Edmunds, L. R., Murali, A., Mills, A., Xie, B., Pangburn, M. M., Sipula, I., Gibson, G., St. Croix, C., Jurczak, M. J.
Published in Scientific reports (10.05.2023)
Published in Scientific reports (10.05.2023)
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Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids
Vatner, Daniel F., Majumdar, Sachin K., Kumashiro, Naoki, Petersen, Max C., Rahimi, Yasmeen, Gattu, Arijeet K., Bears, Mitchell, Camporez, João-Paulo G., Cline, Gary W., Jurczak, Michael J., Samuel, Varman T., Shulman, Gerald I.
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2015)
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Endothelial Uncoupling Protein 2 Regulates Mitophagy and Pulmonary Hypertension During Intermittent Hypoxia
Haslip, Maria, Dostanic, Iva, Huang, Yan, Zhang, Yi, Russell, Kerry S, Jurczak, Michael J, Mannam, Praveen, Giordano, Frank, Erzurum, Serpil C, Lee, Patty J
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2015)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2015)
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CD301b+ Mononuclear Phagocytes Maintain Positive Energy Balance through Secretion of Resistin-like Molecule Alpha
Kumamoto, Yosuke, Camporez, Joao Paulo G., Jurczak, Michael J., Shanabrough, Marya, Horvath, Tamas, Shulman, Gerald I., Iwasaki, Akiko
Published in Immunity (Cambridge, Mass.) (20.09.2016)
Published in Immunity (Cambridge, Mass.) (20.09.2016)
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Cellular Mechanisms by Which FGF21 Improves Insulin Sensitivity in Male Mice
Camporez, João Paulo G, Jornayvaz, François R, Petersen, Max C, Pesta, Dominik, Guigni, Blas A, Serr, Julie, Zhang, Dongyan, Kahn, Mario, Samuel, Varman T, Jurczak, Michael J, Shulman, Gerald I
Published in Endocrinology (Philadelphia) (01.09.2013)
Published in Endocrinology (Philadelphia) (01.09.2013)
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Reversal of Hypertriglyceridemia, Fatty Liver Disease, and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler
Perry, Rachel J., Kim, Taehan, Zhang, Xian-Man, Lee, Hui-Young, Pesta, Dominik, Popov, Violeta B., Zhang, Dongyan, Rahimi, Yasmeen, Jurczak, Michael J., Cline, Gary W., Spiegel, David A., Shulman, Gerald I.
Published in Cell metabolism (05.11.2013)
Published in Cell metabolism (05.11.2013)
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Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice
Birkenfeld, Andreas L., Lee, Hui-Young, Guebre-Egziabher, Fitsum, Alves, Tiago C., Jurczak, Michael J., Jornayvaz, Francois R., Zhang, Dongyang, Hsiao, Jennifer J., Martin-Montalvo, Alejandro, Fischer-Rosinsky, Antje, Spranger, Joachim, Pfeiffer, Andreas F., Jordan, Jens, Fromm, Martin F., König, Jörg, Lieske, Stefanie, Carmean, Christopher M., Frederick, David W., Weismann, Dirk, Knauf, Felix, Irusta, Pablo M., De Cabo, Rafael, Helfand, Stephen L., Samuel, Varman T., Shulman, Gerald I.
Published in Cell metabolism (03.08.2011)
Published in Cell metabolism (03.08.2011)
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Hypophosphatemia promotes lower rates of muscle ATP synthesis
Pesta, Dominik H., Tsirigotis, Dimitrios N., Befroy, Douglas E., Caballero, Daniel, Jurczak, Michael J., Rahimi, Yasmeen, Cline, Gary W., Dufour, Sylvie, Birkenfeld, Andreas L., Rothman, Douglas L., Carpenter, Thomas O., Insogna, Karl, Petersen, Kitt Falk, Bergwitz, Clemens, Shulman, Gerald I.
Published in The FASEB journal (01.10.2016)
Published in The FASEB journal (01.10.2016)
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Cellular Mechanism by Which Estradiol Protects Female Ovariectomized Mice From High-Fat Diet-Induced Hepatic and Muscle Insulin Resistance
Camporez, João Paulo G, Jornayvaz, François R, Lee, Hui-Young, Kanda, Shoichi, Guigni, Blas A, Kahn, Mario, Samuel, Varman T, Carvalho, Carla R.O, Petersen, Kitt Falk, Jurczak, Michael J, Shulman, Gerald I
Published in Endocrinology (Philadelphia) (01.03.2013)
Published in Endocrinology (Philadelphia) (01.03.2013)
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Mitochondrial-Targeted Catalase Protects Against High-Fat Diet-Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation
Lee, Hui-Young, Lee, Jae Sung, Alves, Tiago, Ladiges, Warren, Rabinovitch, Peter S, Jurczak, Michael J, Choi, Cheol Soo, Shulman, Gerald I, Samuel, Varman T
Published in Diabetes (New York, N.Y.) (01.08.2017)
Published in Diabetes (New York, N.Y.) (01.08.2017)
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