Ribonucleotide reductase, a novel drug target for gonorrhea
Narasimhan, Jana, Letinski, Suzanne, Jung, Stephen P, Gerasyuto, Aleksey, Wang, Jiashi, Arnold, Michael, Chen, Guangming, Hedrick, Jean, Dumble, Melissa, Ravichandran, Kanchana, Levitz, Talya, Cui, Chang, Drennan, Catherine L, Stubbe, JoAnne, Karp, Gary, Branstrom, Arthur
Published in eLife (09.02.2022)
Published in eLife (09.02.2022)
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Structure–Activity Relationship (SAR) Optimization of 6‑(Indol-2-yl)pyridine-3-sulfonamides: Identification of Potent, Selective, and Orally Bioavailable Small Molecules Targeting Hepatitis C (HCV) NS4B
Zhang, Nanjing, Zhang, Xiaoyan, Zhu, Jin, Turpoff, Anthony, Chen, Guangming, Morrill, Christie, Huang, Song, Lennox, William, Kakarla, Ramesh, Liu, Ronggang, Li, Chunshi, Ren, Hongyu, Almstead, Neil, Venkatraman, Srikanth, Njoroge, F. George, Gu, Zhengxian, Clausen, Valerie, Graci, Jason, Jung, Stephen P., Zheng, Yingcong, Colacino, Joseph M., Lahser, Fred, Sheedy, Josephine, Mollin, Anna, Weetall, Marla, Nomeir, Amin, Karp, Gary M.
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Identification of PTC725, an Orally Bioavailable Small Molecule That Selectively Targets the Hepatitis C Virus NS4B Protein
Gu, Zhengxian, Graci, Jason D, Lahser, Frederick C, Breslin, Jamie J, Jung, Stephen P, Crona, James H, McMonagle, Patricia, Xia, Ellen, Liu, Shaotang, Karp, Gary, Zhu, Jin, Huang, Song, Nomeir, Amin, Weetall, Marla, Almstead, Neil G, Peltz, Stuart W, Tong, Xiao, Ralston, Robert, Colacino, Joseph M
Published in Antimicrobial Agents and Chemotherapy (01.07.2013)
Published in Antimicrobial Agents and Chemotherapy (01.07.2013)
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Inhibiting Expression of Specific Genes in Mammalian Cells with 5′ End-Mutated U1 Small Nuclear RNAs Targeted to Terminal Exons of Pre-mRNA
Fortes, Puri, Cuevas, Yolanda, Guan, Fei, Liu, Peng, Pentlicky, Sara, Jung, Stephen P., Martínez-Chantar, Maria L., Prieto, Jesús, Rowe, David, Gunderson, Samuel I.
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2003)
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Development of an oral treatment that rescues gait ataxia and retinal degeneration in a phenotypic mouse model of familial dysautonomia
Morini, Elisabetta, Chekuri, Anil, Logan, Emily M., Bolduc, Jessica M., Kirchner, Emily G., Salani, Monica, Krauson, Aram J., Narasimhan, Jana, Gabbeta, Vijayalakshmi, Grover, Shivani, Dakka, Amal, Mollin, Anna, Jung, Stephen P., Zhao, Xin, Zhang, Nanjing, Zhang, Sophie, Arnold, Michael, Woll, Matthew G., Naryshkin, Nikolai A., Weetall, Marla, Slaugenhaupt, Susan A.
Published in American journal of human genetics (02.03.2023)
Published in American journal of human genetics (02.03.2023)
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PTC725, an NS4B-Targeting Compound, Inhibits a Hepatitis C Virus Genotype 3 Replicon, as Predicted by Genome Sequence Analysis and Determined Experimentally
Graci, Jason D, Jung, Stephen P, Pichardo, John, Lahser, Frederick, Tong, Xiao, Gu, Zhengxian, Colacino, Joseph M
Published in Antimicrobial agents and chemotherapy (01.12.2016)
Published in Antimicrobial agents and chemotherapy (01.12.2016)
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Discovery of 2-(4-sulfonamidophenyl)-indole 3-carboxamides as potent and selective inhibitors with broad hepatitis C virus genotype activity targeting HCV NS4B
Zhang, Nanjing, Turpoff, Anthony, Zhang, Xiaoyan, Huang, Song, Liu, Yalei, Almstead, Neil, Njoroge, F. George, Gu, Zhengxian, Graci, Jason, Jung, Stephen P., Pichardo, John, Colacino, Joseph, Lahser, Fred, Ingravallo, Paul, Weetall, Marla, Nomeir, Amin, Karp, Gary M.
Published in Bioorganic & medicinal chemistry letters (15.01.2016)
Published in Bioorganic & medicinal chemistry letters (15.01.2016)
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6-(Azaindol-2-yl)pyridine-3-sulfonamides as potent and selective inhibitors targeting hepatitis C virus NS4B
Chen, Guangming, Ren, Hongyu, Zhang, Nanjing, Lennox, William, Turpoff, Anthony, Paget, Steven, Li, Chunshi, Almstead, Neil, Njoroge, F. George, Gu, Zhengxian, Graci, Jason, Jung, Stephen P., Colacino, Joseph, Lahser, Fred, Zhao, Xin, Weetall, Marla, Nomeir, Amin, Karp, Gary M.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Requirements for gene silencing mediated by U1 snRNA binding to a target sequence
Abad, Xabi, Vera, Maria, Jung, Stephen P, Oswald, Evelyn, Romero, Inés, Amin, Vaibhav, Fortes, Puri, Gunderson, Samuel I
Published in Nucleic acids research (01.04.2008)
Published in Nucleic acids research (01.04.2008)
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Expression of PRL-1 nuclear PTPase is associated with proliferation in liver but with differentiation in intestine
Diamond, R H, Peters, C, Jung, S P, Greenbaum, L E, Haber, B A, Silberg, D G, Traber, P G, Taub, R
Published in The American journal of physiology (01.07.1996)
Published in The American journal of physiology (01.07.1996)
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