Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease
Burbulla, Lena F., Song, Pingping, Mazzulli, Joseph R., Zampese, Enrico, Wong, Yvette C., Jeon, Sohee, Santos, David P., Blanz, Judith, Obermaier, Carolin D., Strojny, Chelsee, Savas, Jeffrey N., Kiskinis, Evangelos, Zhuang, Xiaoxi, Krüger, Rejko, Surmeier, D. James, Krainc, Dimitri
Published in Science (American Association for the Advancement of Science) (22.09.2017)
Published in Science (American Association for the Advancement of Science) (22.09.2017)
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LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance
Rothaug, Michelle, Zunke, Friederike, Mazzulli, Joseph R., Schweizer, Michaela, Altmeppen, Hermann, Lüllmann-Rauch, Renate, Kallemeijn, Wouter W., Gaspar, Paulo, Aerts, Johannes M., Glatzel, Markus, Saftig, Paul, Krainc, Dimitri, Schwake, Michael, Blanz, Judith
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.2014)
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Journal Article
Lysosomal membrane proteins: life between acid and neutral conditions
Saftig, Paul, Schröder, Bernd, Blanz, Judith
Published in Biochemical Society transactions (01.12.2010)
Published in Biochemical Society transactions (01.12.2010)
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Journal Article
Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina
Notomi, Shoji, Ishihara, Kenji, Efstathiou, Nikolaos E., Lee, Jong-Jer, Hisatomi, Toshio, Tachibana, Takashi, Konstantinou, Eleni K., Ueta, Takashi, Murakami, Yusuke, Maidana, Daniel E., Ikeda, Yasuhiro, Kume, Shinji, Terasaki, Hiroto, Sonoda, Shozo, Blanz, Judith, Young, Lucy, Sakamoto, Taiji, Sonoda, Koh-Hei, Saftig, Paul, Ishibashi, Tatsuro, Miller, Joan W., Kroemer, Guido
Published in Proceedings of the National Academy of Sciences - PNAS (19.11.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (19.11.2019)
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Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2
Zunke, Friederike, Andresen, Lisa, Wesseler, Sophia, Groth, Johann, Arnold, Philipp, Rothaug, Michelle, Mazzulli, Joseph R., Krainc, Dimitri, Blanz, Judith, Saftig, Paul, Schwake, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2016)
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Journal Article
LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease
Rothaug, Michelle, Stroobants, Stijn, Schweizer, Michaela, Peters, Judith, Zunke, Friederike, Allerding, Mirka, D'Hooge, Rudi, Saftig, Paul, Blanz, Judith
Published in Acta neuropathologica communications (31.01.2015)
Published in Acta neuropathologica communications (31.01.2015)
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Journal Article
Long-term enzyme replacement therapy improves neurocognitive functioning and hippocampal synaptic plasticity in immune-tolerant alpha-mannosidosis mice
Stroobants, Stijn, Damme, Markus, Van der Jeugd, Ann, Vermaercke, Ben, Andersson, Claes, Fogh, Jens, Saftig, Paul, Blanz, Judith, D'Hooge, Rudi
Published in Neurobiology of disease (01.10.2017)
Published in Neurobiology of disease (01.10.2017)
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Journal Article
Lysosome-Associated Membrane Proteins (LAMP) Maintain Pancreatic Acinar Cell Homeostasis: LAMP-2–Deficient Mice Develop Pancreatitis
Mareninova, Olga A, Sendler, Matthias, Malla, Sudarshan Ravi, Yakubov, Iskandar, French, Samuel W, Tokhtaeva, Elmira, Vagin, Olga, Oorschot, Viola, Lüllmann-Rauch, Renate, Blanz, Judith, Dawson, David, Klumperman, Judith, Lerch, Markus M, Mayerle, Julia, Gukovsky, Ilya, Gukovskaya, Anna S
Published in Cellular and molecular gastroenterology and hepatology (01.11.2015)
Published in Cellular and molecular gastroenterology and hepatology (01.11.2015)
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Journal Article
Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy
Kleinecke, Sandra, Richert, Sarah, de Hoz, Livia, Brügger, Britta, Kungl, Theresa, Asadollahi, Ebrahim, Quintes, Susanne, Blanz, Judith, McGonigal, Rhona, Naseri, Kobra, Sereda, Michael W, Sachsenheimer, Timo, Lüchtenborg, Christian, Möbius, Wiebke, Willison, Hugh, Baes, Myriam, Nave, Klaus-Armin, Kassmann, Celia Michèle
Published in eLife (04.05.2017)
Published in eLife (04.05.2017)
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Role of LAMP-2 in lysosome biogenesis and autophagy
Eskelinen, Eeva-Liisa, Illert, Anna Lena, Tanaka, Yoshitaka, Schwarzmann, Günter, Blanz, Judith, Von Figura, Kurt, Saftig, Paul
Published in Molecular biology of the cell (01.09.2002)
Published in Molecular biology of the cell (01.09.2002)
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Journal Article
Role for LAMP‐2 in endosomal cholesterol transport
Schneede, Alexander, Schmidt, Christine K., Hölttä‐Vuori, Maarit, Heeren, Jörg, Willenborg, Marion, Blanz, Judith, Domanskyy, Mykola, Breiden, Bernadette, Brodesser, Susanne, Landgrebe, Jobst, Sandhoff, Konrad, Ikonen, Elina, Saftig, Paul, Eskelinen, Eeva‐Liisa
Published in Journal of cellular and molecular medicine (01.02.2011)
Published in Journal of cellular and molecular medicine (01.02.2011)
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Journal Article
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice
Saftig, Paul, Tanaka, Yoshitaka, Guhde, Gundula, Suter, Anke, Eskelinen, Eeva-Liisa, Hartmann, Dieter, Lüllmann-Rauch, Renate, Janssen, Paul M. L, Blanz, Judith, von Figura, Kurt
Published in Nature (London) (24.08.2000)
Published in Nature (London) (24.08.2000)
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Journal Article
Structural Determinants of M-Type KCNQ (Kv7) K+ Channel Assembly
Schwake, Michael, Athanasiadu, Despina, Beimgraben, Christian, Blanz, Judith, Beck, Christian, Jentsch, Thomas J, Saftig, Paul, Friedrich, Thomas
Published in The Journal of neuroscience (05.04.2006)
Published in The Journal of neuroscience (05.04.2006)
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Journal Article
Sequestration of cholesterol within the host late endocytic pathway restricts liver-stage Plasmodium development
Petersen, Wiebke, Stenzel, Werner, Silvie, Olivier, Blanz, Judith, Saftig, Paul, Matuschewski, Kai, Ingmundson, Alyssa
Published in Molecular biology of the cell (15.03.2017)
Published in Molecular biology of the cell (15.03.2017)
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Journal Article
LIMP-2 Is a Receptor for Lysosomal Mannose-6-Phosphate-Independent Targeting of β-Glucocerebrosidase
Reczek, David, Schwake, Michael, Schröder, Jenny, Hughes, Heather, Blanz, Judith, Jin, Xiaoying, Brondyk, William, Van Patten, Scott, Edmunds, Tim, Saftig, Paul
Published in Cell (16.11.2007)
Published in Cell (16.11.2007)
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Journal Article
Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand β-glucocerebrosidase
Blanz, Judith, Groth, Johann, Zachos, Christina, Wehling, Christina, Saftig, Paul, Schwake, Michael
Published in Human molecular genetics (15.02.2010)
Published in Human molecular genetics (15.02.2010)
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Journal Article
Mannose 6‐phosphate‐independent Lysosomal Sorting of LIMP‐2
Blanz, Judith, Zunke, Friederike, Markmann, Sandra, Damme, Markus, Braulke, Thomas, Saftig, Paul, Schwake, Michael
Published in Traffic (Copenhagen, Denmark) (01.10.2015)
Published in Traffic (Copenhagen, Denmark) (01.10.2015)
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Journal Article
The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2
Demirel, Özlem, Jan, Irina, Wolters, Dirk, Blanz, Judith, Saftig, Paul, Tampé, Robert, Abele, Rupert
Published in Journal of cell science (15.09.2012)
Published in Journal of cell science (15.09.2012)
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