Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue
Kollmer, Marius, Close, William, Funk, Leonie, Rasmussen, Jay, Bsoul, Aref, Schierhorn, Angelika, Schmidt, Matthias, Sigurdson, Christina J., Jucker, Mathias, Fändrich, Marcus
Published in Nature communications (29.10.2019)
Published in Nature communications (29.10.2019)
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Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids
Pérez, María José, Ivanyuk, Dina, Panagiotakopoulou, Vasiliki, Di Napoli, Gabriele, Kalb, Stefanie, Brunetti, Dario, Al-Shaana, Rawaa, Kaeser, Stephan A., Fraschka, Sabine Anne-Kristin, Jucker, Mathias, Zeviani, Massimo, Viscomi, Carlo, Deleidi, Michela
Published in Molecular psychiatry (01.10.2021)
Published in Molecular psychiatry (01.10.2021)
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Innate immune memory in the brain shapes neurological disease hallmarks
Wendeln, Ann-Christin, Degenhardt, Karoline, Kaurani, Lalit, Gertig, Michael, Ulas, Thomas, Jain, Gaurav, Wagner, Jessica, Häsler, Lisa M., Wild, Katleen, Skodras, Angelos, Blank, Thomas, Staszewski, Ori, Datta, Moumita, Centeno, Tonatiuh Pena, Capece, Vincenzo, Islam, Md. Rezaul, Kerimoglu, Cemil, Staufenbiel, Matthias, Schultze, Joachim L., Beyer, Marc, Prinz, Marco, Jucker, Mathias, Fischer, André, Neher, Jonas J.
Published in Nature (London) (19.04.2018)
Published in Nature (London) (19.04.2018)
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Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life
Uhlmann, Ruth E., Rother, Christine, Rasmussen, Jay, Schelle, Juliane, Bergmann, Carina, Ullrich Gavilanes, Emily M., Fritschi, Sarah K., Buehler, Anika, Baumann, Frank, Skodras, Angelos, Al-Shaana, Rawaa, Beschorner, Natalie, Ye, Lan, Kaeser, Stephan A., Obermüller, Ulrike, Christensen, Søren, Kartberg, Fredrik, Stavenhagen, Jeffrey B., Rahfeld, Jens-Ulrich, Cynis, Holger, Qian, Fang, Weinreb, Paul H., Bussiere, Thierry, Walker, Lary C., Staufenbiel, Matthias, Jucker, Mathias
Published in Nature neuroscience (01.12.2020)
Published in Nature neuroscience (01.12.2020)
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Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases
Bacioglu, Mehtap, Maia, Luis F., Preische, Oliver, Schelle, Juliane, Apel, Anja, Kaeser, Stephan A., Schweighauser, Manuel, Eninger, Timo, Lambert, Marius, Pilotto, Andrea, Shimshek, Derya R., Neumann, Ulf, Kahle, Philipp J., Staufenbiel, Matthias, Neumann, Manuela, Maetzler, Walter, Kuhle, Jens, Jucker, Mathias
Published in Neuron (Cambridge, Mass.) (06.07.2016)
Published in Neuron (Cambridge, Mass.) (06.07.2016)
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Transmission and spreading of tauopathy in transgenic mouse brain
Crowther, R. Anthony, Clavaguera, Florence, Abramowski, Dorothee, Goedert, Michel, Bolmont, Tristan, Probst, Alphonse, Tolnay, Markus, Fraser, Graham, Staufenbiel, Matthias, Stalder, Anna K, Jucker, Mathias, Beibel, Martin, Frank, Stephan
Published in Nature cell biology (01.07.2009)
Published in Nature cell biology (01.07.2009)
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CSF p-tau increase in response to Aβ-type and Danish-type cerebral amyloidosis and in the absence of neurofibrillary tangles
Kaeser, Stephan A., Häsler, Lisa M., Lambert, Marius, Bergmann, Carina, Bottelbergs, Astrid, Theunis, Clara, Mercken, Marc, Jucker, Mathias
Published in Acta neuropathologica (01.02.2022)
Published in Acta neuropathologica (01.02.2022)
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Homeostatic and injury‐induced microglia behavior in the aging brain
Hefendehl, Jasmin K., Neher, Jonas J., Sühs, Rafael B., Kohsaka, Shinichi, Skodras, Angelos, Jucker, Mathias
Published in Aging cell (01.02.2014)
Published in Aging cell (01.02.2014)
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Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease
Rasmussen, Jay, Mahler, Jasmin, Beschorner, Natalie, Kaeser, Stephan A., Häsler, Lisa M., Baumann, Frank, Nyström, Sofie, Portelius, Erik, Blennow, Kaj, Lashley, Tammaryn, Fox, Nick C., Sepulveda-Falla, Diego, Glatzel, Markus, Oblak, Adrian L., Ghetti, Bernardino, Nilsson, K. Peter R., Hammarström, Per, Staufenbiel, Matthias, Walker, Lary C., Jucker, Mathias
Published in Proceedings of the National Academy of Sciences - PNAS (05.12.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (05.12.2017)
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White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease
Araque Caballero, Miguel Ángel, Suárez-Calvet, Marc, Duering, Marco, Franzmeier, Nicolai, Benzinger, Tammie, Fagan, Anne M, Bateman, Randall J, Jack, Clifford R, Levin, Johannes, Dichgans, Martin, Jucker, Mathias, Karch, Celeste, Masters, Colin L, Morris, John C, Weiner, Michael, Rossor, Martin, Fox, Nick C, Lee, Jae-Hong, Salloway, Stephen, Danek, Adrian, Goate, Alison, Yakushev, Igor, Hassenstab, Jason, Schofield, Peter R, Haass, Christian, Ewers, Michael
Published in Brain (London, England : 1878) (01.10.2018)
Published in Brain (London, England : 1878) (01.10.2018)
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Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells
Varvel, Nicholas H, Grathwohl, Stefan A, Baumann, Frank, Liebig, Christian, Bosch, Andrea, Brawek, Bianca, Thal, Dietmar R, Charo, Israel F, Heppner, Frank L, Aguzzi, Adriano, Garaschuk, Olga, Ransohoff, Richard M, Jucker, Mathias
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2012)
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Dynamics of the Microglial/Amyloid Interaction Indicate a Role in Plaque Maintenance
Bolmont, Tristan, Haiss, Florent, Eicke, Daniel, Radde, Rebecca, Mathis, Chester A, Klunk, William E, Kohsaka, Shinichi, Jucker, Mathias, Calhoun, Michael E
Published in The Journal of neuroscience (16.04.2008)
Published in The Journal of neuroscience (16.04.2008)
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Induction of cerebral β-amyloidosis: Intracerebral versus systemic Aβ inoculation
Eisele, Yvonne S, Bolmont, Tristan, Heikenwalder, Mathias, Langer, Franziska, Jacobson, Laura H, Yan, Zheng-Xin, Roth, Klaus, Aguzzi, Adriano, Staufenbiel, Matthias, Walker, Lary C, Jucker, Mathias
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2009)
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Aβ42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
Radde, Rebecca, Bolmont, Tristan, Kaeser, Stephan A, Coomaraswamy, Janaky, Lindau, Dennis, Stoltze, Lars, Calhoun, Michael E, Jäggi, Fabienne, Wolburg, Hartwig, Gengler, Simon, Haass, Christian, Ghetti, Bernardino, Czech, Christian, Hölscher, Christian, Mathews, Paul M, Jucker, Mathias
Published in EMBO reports (01.09.2006)
Published in EMBO reports (01.09.2006)
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